Clinical trials: open to volunteers, in Pakistan
Frozen Shoulder
Effects of Posterior Capsular Stretching With and Without Dynamic Neuromuscular Stabilization Exercises in Frozen Shoulder
The goal of this clinical trial is to determine the effects of posterior capsular stretching with and without Dynamic Neuromuscular Stabilization (DNS) exercises on pain, shoulder internal rotation deficit, disability, and…
- Trial name
- NCT07905417
- Testing
- Posterior Capsular Stretching with Dynamic Neuromuscular Stabilization, Posterior Capsular Stretching
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Management and Technology Lahore
Chronic Non-Specific Low Back Pain
McGill Stabilization Exercises Versus Pilates for Chronic Low Back Pain
The goal of this clinical trial is to compare the effects of McGill Stabilization Exercises and Pilates on pain, muscle thickness, lumbar flexibility, and disability in adults aged 30-50 years with chronic non-specific low back…
- Trial name
- NCT07905391
- Testing
- McGill Stabilization Exercises, Pilates
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Management and Technology Lahore
Farward Head Posture
Effect of Excercises on Pain , Disability and Craniovertebral Angle in Patients With Forward Head Posture.
A total of 18 treatment sessions will be conducted over six weeks (three sessions per week). Both groups will receive a hot pack for 7-8 minutes before treatment.
- Trial name
- NCT07905092
- Testing
- Kendall Posture Correction, Scapular Stabilization Exercises
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Management and Technology Lahore
Pain
Anesthetic Effectiveness of Mental/Incisive Nerve Block Versus Inferior Nerve Block Using 4% Articaine and 2% Lidocaine in Mandibular First and Second Premolars With Symptomatic Irreversible Pulpitis.
The purpose of this study is to check the anesthetic effectiveness of 4% Articaine and 2% Lidocaine in IANB Vs Mental nerve block in 1st and 2nd premolars with symptomatic Irreversible Pulpitis.
- Trial name
- NCT07905196
- Testing
- Group A : MINB with 2% Lidocaine HCL+ 1:1000,000 Epinephrine - 1.8 ml, Group B : MINB with 4% Articaine HCL + 1:1000,000 Epinephrine - 1.8 ml, Group C : IANB with 2% Lidocaine HCL + 1:1000,000 Epinephrine - 1.8 ml
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Foundation University Islamabad
SLE - Systemic Lupus Erythematosus
Pakistan Arthritis and Connective Tissue Disease Network - Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects individuals globally, yet there is a significant lack of data regarding its prevalence and management, particularly in Asian populations like…
- Trial name
- PAN-SLE (NCT07902622)
- Testing
- no active ingredient
- Where
- Pakistan
- Volunteers
- 3,000 people
- Sponsor
- Foundation University Islamabad
Diabetic Peripheral Neuropathy
Effects of Perturbation-Based Versus Conventional Balance Training on Reactive Stepping Ability in Patients With Diabetic Peripheral Neuropathy
This study will compare perturbation-based balance training (PBBT) with conventional balance training in patients with diabetic peripheral neuropathy to assess reactive stepping ability, dynamic balance, and functional balance.
- Trial name
- NCT07902297
- Testing
- Perturbation-Based Balance Training (PBBT), Conventional Balance Training (CBT)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Diabetic Foot Ulcer
Comparison of Negative Pressure Wound Therapy Versus Moist Wound Dressing in Diabetic Foot Ulcer Patients
Diabetic foot ulcer is a common and disabling complication of diabetes mellitus. This randomized controlled trial will be conducted at Abbas Institute of Medical Sciences, Muzaffarabad to compare the efficacy of negative pressure…
- Trial name
- NCT07898202
- Testing
- Negative Pressure Wound Therapy, Moist Wound Dressing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Abbas Institute of Medical Sciences
Stroke
Effects of Mirror Therapy and Motor Imagery on Upper Limb Motor Functions in Middle Cerebral Artery Stroke
This study will compare mirror therapy (MT) with motor imagery (MI), each added to routine Bobath-based physical therapy, to assess upper limb motor function and functional independence in patients with subacute middle cerebral…
- Trial name
- NCT07902284
- Testing
- Mirror Therapy, Motor Imagery, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke
Effects of Contralateral Gravity Eliminated Gluteus Medius and Ipsilateral Quadratus Lumborum Strengthening on Pelvic Alignment, Balance and Functional Mobility on Subacute Stroke Patients
This study aims to compare the effects of contralateral gravity-eliminated gluteus medius strengthening and ipsilateral quadratus lumborum strengthening, both combined with conventional physiotherapy, on pelvic alignment…
- Trial name
- NCT07902310
- Testing
- Contralateral Gravity-Eliminated Gluteus Medius Strengthening, Quadratus Lumborum Strengthening Group, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Glycogen Storage Disease Type II, Pompe Disease
Pompe Disease Registry Protocol
The Pompe Registry is a global, multicenter, international, longitudinal, observational, and voluntary program for patients with Pompe disease, designed to track the disease's natural history and outcomes in patients, both…
- Trial name
- NCT00231400
- Where
- 282 sites in United States, Argentina and 42 more
- Volunteers
- 2,000 people
- Sponsor
- Genzyme, a Sanofi Company
Niemann-Pick Type C Disease
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)
An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of Niemann-Pick type C disease
- Trial name
- NCT07082725
- Testing
- Nizubaglustat
- Where
- 34 sites in United States, Argentina and 13 more
- Volunteers
- 72 people
- Sponsor
- Azafaros B.V.
Heat Illness, Quality of Life
Structural Heat Adaptation and Education in Urban Setting
This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and improve quality of life during periods of…
- Trial name
- SHAPES (NCT06991543)
- Testing
- Community education and awareness, and personal lifestyle and cooling behavior modification, Participatory local structural and environmental heat mitigation solutions
- Where
- Pakistan
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Acute Kidney Injury, Fluid Overload
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
There is a growing focus on short- and long-term kidney health in neonates, including those with acute kidney injury (AKI). AKI occurs commonly in the Neonatal Intensive Care Unit (NICU) and is associated with adverse outcomes.
- Conditions
- Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors
- Trial name
- AWAKEN 2 (NCT06823115)
- Where
- 125 sites in United States, Argentina and 31 more
- Volunteers
- 8,000 people
- Sponsor
- Indiana University
ST-Elevation Myocardial Infarction (STEMI)
Reducing Slow/No-Reflow With Prophylactic High-Dose Intracoronary Adenosine Protocol in ST-Elevation Myocardial Infarction The REFLOW AMI Trial
The REFLOW AMI Trial aims to determine whether prophylactic high-dose intracoronary adenosine reduces slow-flow or no-reflow (SNR) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous…
- Trial name
- REFLOW AMI (NCT07898696)
- Testing
- Adenosine, Standard Treatment only
- Where
- 2 sites in Pakistan
- Volunteers
- 660 people
- Sponsor
- Prof Muzaffar Ali Zahidi
Diabetic Macular Edema (DME)
Suprachoroidal Bevacizumab Versus Intravitreal Bevacizumab in Diabetic Macular Edema
Diabetic macular edema is an eye condition caused by diabetes in which fluid accumulates in the central part of the retina, leading to blurred vision and potentially permanent vision loss.
- Trial name
- Macular Edema (NCT07897630)
- Testing
- Bevacizumab
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Tuberculosis Diagnosis
Evaluation of New TB Diagnostic Tests (NATs) in Pakistan
This study evaluates two portable molecular tests for tuberculosis (TB), Pluslife MTBC and Ustar PortNAT, during community-based active case-finding activities in Pakistan.
- Trial name
- TB (NCT06984887)
- Testing
- Paired tongue-swab and sputum-based molecular testing for tuberculosis
- Where
- 2 sites in Pakistan
- Volunteers
- 6,100 people, healthy volunteers welcome
- Sponsor
- Mercy Corps Pakistan
Anesthetic Efficacy
Comparison of Anesthetic Efficacy OF 2% Lidocaine Inferior Alveolar Nerve (IANB) Block Versus Primary Buccal Infilteration With 4% Articaine in Symptomatic Irreversible Pulpitis(SIP) IN Mandibular First Molars
This randomized controlled trial aims to compare the anesthetic efficacy of 2% lignocaine administered through an inferior alveolar nerve block (IANB) in one group of participants with 4% articaine delivered via primary buccal…
- Trial name
- IANB SIP EPT (NCT07409896)
- Testing
- INTERVENTION 1: 2% Lignocaine 1:80,000 epinephrine, INTERVENTION 2 : 4%Articaine 1:100,000 epinephrine
- Where
- Pakistan
- Volunteers
- 330 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Obesity & Overweight, Obesity Type I and II
Impact of Significant Surgical Reduction of Adipose Tissue on Plasma Levels and Genetic Expression of Adipokines Associated With Ischemic Heart Disease in Type I Obesity.
Adipose tissue is with endocrine properties and secretes many cytokines. Some of these cytokines are concerned with ischemic heart disease.
- Trial name
- NCT07897682
- Testing
- Liposuction
- Where
- Pakistan
- Volunteers
- 212 people
- Sponsor
- King Edward Medical University
Gingivitis
Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for Gingivitis
The goal of this clinical trial is to learn if daily oil pulling with coconut oil or sesame oil works as effectively as a standard mouthwash to treat gum swelling and redness (gingivitis) in adults aged 18 to 55 years.
- Trial name
- NCT07892235
- Testing
- coconut oil, Sesame Oil, 0.2% Chlorhexidine Mouthwash
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Bahria University
Episiotomy , Perineal Pain
Pudendal Nerve Block for Pain Relief During Episiotomy Repair
Episiotomy is a surgical cut made in the perineum, the area between the vagina and anus, during vaginal childbirth. Repairing an episiotomy can cause pain, and adequate pain relief is important for maternal comfort during and…
- Trial name
- NCT07883473
- Testing
- Pudendal Nerve Block, Conventional Local Perineal Infiltration, Lignocaine Hydrochloride (Lidocaine Hydrochloride) 2% injection
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.