Clinical trials: in Pakistan
Sarcopenia
Ursolic Acid-Standardized Apple Phospholipid-formulated Supplementation for Muscle Strength and Physical Performance in Older Adults With Mild Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Trial
Sarcopenia is an age-related condition characterized by loss of muscle strength and physical performance, leading to increased risk of falls and disability.
- Trial name
- NCT07562698
- Testing
- Ursolic Acid-Standardized Apple Pomace Extract
- Where
- Pakistan
- Volunteers
- 105 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Chronic Non-Specific Neck Pain
Effects of Telerehabilitation and Supervised Clinic Based Rehab With Pain Neuroscience Education for Pain,Kinesiophobia and Functional Disability Among Chronic Non-Specific Neck Pain Patients
Chronic non-specific neck pain is a common musculoskeletal condition affecting a large proportion of the population worldwide. It is characterized by persistent neck pain lasting more than three months without a specific…
- Trial name
- NCT07617623
- Testing
- Telerehabilitation with Pain Neuroscience Education, Supervised Clinic Based Rehab with Pain Neuroscience Education
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Odontogenic Infection, Maxillofacial Infection
Moxifloxacin Versus Clindamycin in the Management of Odontogenic Maxillofacial Infectious Processes
Investigators are conducting a trial to compare moxifloxacin against clindamycin for dental infections that spread to the face and jaw.
- Conditions
- Odontogenic Infection, Maxillofacial Infection, Cellulitis, Cellulitis of Face
- Trial name
- NCT07810244
- Testing
- Clindamycin, Moxifloxacin (400 mg)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Dental Anxiety, Music Intervention
Effect of Music on Dental Anxiety and Physiological Responses During Dental Drill and Suction Sounds
Dental anxiety is common and may be triggered or increased by sounds associated with dental treatment, particularly the sound of a dental drill and suction device.
- Trial name
- MUS-DENT (NCT07827118)
- Testing
- Music intervention
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Unilateral S1 Nerve Root Pain
Comparison of Efficacy of Caudal Versus Transforaminal Epidural Steroid Injections in Unilateral S1 Nerve Root Pain: A Randomized Controlled Trial
This study compares caudal and transforaminal epidural steroid injections for treating unilateral S1 nerve root pain. It evaluates pain relief, functional improvement, treatment satisfaction, quality of life, and complications…
- Trial name
- NCT07833553
- Testing
- Caudal Epidural Steroid Injection (CEI), Transforaminal Epidural Steroid Injection (TFI)
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Health Sciences Lahore
Forward Head Posture
Comparative Effects of Pressure and Visual Biofeedback Training on Pain, Disability, Range of Motion Among Patients With Forward Head Posture Correction: A Randomized Controlled Trial
The study will take place at Akbar Niazi Teaching Hospital and AL kauther International hospital, Bhara Kahu, Islamabad with formal permission obtained from the institution.
- Trial name
- NCT07856433
- Testing
- VISUAL FEEDBACK, Pressure Biofeedback
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
Tourniquet-induced Pain, Procedural Pain
Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia.
- Trial name
- NCT07878962
- Testing
- Dexmedetomidine, ketorolac, Lidocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Mayo Hospital Lahore
Obesity, Overweight
Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity
Obesity and its related illnesses have become serious health issues, obesity is today the fifth most common cause of death. Obesity rate has dramatically enhanced in both male and female, and across all ages.
- Trial name
- NCT05822167
- Testing
- High Protein Meal at Cold Temperature, High Protein Meal at Warm Temperarute, High Protein Meal at Hot Temperature
- Where
- Pakistan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Wilson's Disease
Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients.
The goal of this clinical trial is to learn if a new trientine tetrahydrochloride (TETA 4HCl) formulation administered once a day compared to d-Penicillamine (DPA) as a first line treatment for people living with Wilson's disease…
- Trial name
- TRADITiONAL (NCT07465718)
- Testing
- TETA 4HCl formulation, D-Penicillamine
- Where
- 10 sites in United States, China and 2 more
- Volunteers
- 38 people
- Sponsor
- Orphalan
Quality of Life, Sleep
Effect of Simha Pranayama and Bhramari Pranayama Relaxation Technique on Sleep and Quality of Life
Day end work related mental and muscular tension is quite common among young healthy individuals. This tension dramatically disturb sleeping pattern which also effects QoL.
- Trial name
- NCT07729267
- Testing
- Simha pranayama, Bhramari Pranayama
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mohtishim Ahmed
Pulmonary Disease, Chronic Obstructive (COPD)
Comparative Effects of Coherent Breathing and Regular Paced Breathing on Dyspnea and Pulmonary Function in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory condition of airways characterized by recurrent episodes of coughing, respiratory muscle weakness, lung hyperinflation and air trapping which ultimately leads to…
- Trial name
- NCT07875036
- Testing
- Coherent Breathing Group A, Regular Paced Breathing Group B
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Foundation University Islamabad
Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery
Additional Effects of Flutter With Conventional Chest Physiotherapy on Peak Expiratory Flow Rate and Chest Expansion in Post CABG Patients With COPD
Flutter therapy is an oscillating positive expiratory pressure (OPEP) technique that combines positive expiratory pressure with airway oscillations to facilitate mobilization and clearance of respiratory secretions.
- Conditions
- Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07875049
- Testing
- Conventional Chest Physiotherapy, Flutter device with conventional chest physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Foundation University Islamabad
Polycystic Ovarian Syndrome (PCOS), Quality of Life
High Intensity Interval Training Versus Mat Pilates in Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is associated with obesity, insulin resistance, poor physical fitness, and reduced quality of life.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Quality of Life, Physical Fitness
- Trial name
- NCT07875400
- Testing
- High-Intensity Interval Training (HIIT), Mat Pilates group, General mobility exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Postmenopausal Osteoporosis
Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis
This randomized controlled trial aims to compare the effects of sensorimotor-based balance training and digitally augmented core stabilization on postural control and fall risk in postmenopausal women with osteoporosis.
- Trial name
- NCT07875894
- Testing
- Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Dental Anxiety in Children, Child Behaviour
Comparative Evaluation of Intranasal Atomized Midazalom Combined With Nitrous Oxide Versus Nitrous Oxide Monotherapy
The rationale of this trial is to evaluate whether combining intranasal atomized midazolam with nitrous oxide offers better behavior management leading to successful treatment completion in comparison with using nitrous oxide…
- Trial name
- NCT07876024
- Testing
- Midazolam (Intranasal), Nitrous oxide/oxygen inhalation sedation alone
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Gaucher Disease, Cerebroside Lipidosis Syndrome
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status.
- Conditions
- Gaucher Disease, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease, Glucosylceramide Beta-Glucosidase Deficiency Disease
- Trial name
- NCT00358943
- Where
- 317 sites in United States, Argentina and 50 more
- Volunteers
- 12,000 people
- Sponsor
- Genzyme, a Sanofi Company
Chronic Low-back Pain
Comparative Effects of Mulligan Straight Leg Raise Technique Versus Slump Stretching on Pain, Disability and Hip Range of Motion in Patients With Chronic Low Back Pain.
The goal of this clinical trial is to examine the effect of mulligan straight leg raise versus slump stretching on pain, disability and hip range of motion in patient with low back pain. .
- Trial name
- NCT05779891
- Testing
- Mulligan Traction Straight Leg Raise Technique, Slump Stretching
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
ACL Reconstruction
Effects of Blood Flow Restriction Training and Instrument-Assisted Soft Tissue Mobilization for Pain, Strength, Range of Motion, and Kinesiophobia Among ACL Reconstruction Patients.
This randomized clinical trial aims to compare the effects of Blood Flow Restriction Training (BFR) and Instrument-Assisted Soft Tissue Mobilization (IASTM) on pain, quadriceps muscle strength, knee range of motion (ROM), and…
- Trial name
- NCT07662850
- Testing
- Blood Flow Restriction Training, Instrument-Assisted Soft Tissue Mobilization (IASTM)
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke, Hemiplegia
Visual and Auditory Electromyography Biofeedback Among Stroke Patients
Stroke commonly results in impairments of balance, mobility, and lower extremity motor function that limit independence in daily activities.
- Conditions
- Stroke, Hemiplegia, Stroke Rehabilitation
- Trial name
- NCT07710937
- Testing
- Visual Electromyography Biofeedback, Auditory Electromyography Biofeedback, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Alveolar Osteitis
Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis
This study will compare the effectiveness of amoxicillin, metronidazole, and chlorhexidine in preventing alveolar osteitis (dry socket) following lower third molar extraction.
- Trial name
- NCT07833176
- Testing
- Amoxicillin, Metronidazole, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
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