Clinical trials: open to volunteers, in Pakistan
Cerebral Palsy Children
Effects of Universal Exercise Unit Therapy With Task-oriented Training in CP Children
Cerebral palsy is a problem that affects the development and motor skills caused by early non-progressive central nervous system damage.
- Trial name
- NCT06637579
- Testing
- universal exercise unit therapy with task oriented strength training, Task-oriented training for gross motor functioning
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Riphah International University
Ataxic Cerebral Palsy, Coordination and Balance Disturbances
Effects of Hand Arm Bimanual Intensive Therapy Including Lower Extremity on Balance and Coordination in Ataxic Cerebral Palsy
Ataxic cerebral palsy is an abnormal movement or posture pattern accompanied by a loss of coordinated muscle action, resulting in movements that lack proper force, rhythm, or accuracy.
- Trial name
- NCT06639802
- Testing
- Hand Arm Bimanual Intensive therapy including lower extremity (HABIT-ILE)
- Where
- Pakistan
- Volunteers
- 23 people
- Sponsor
- Foundation University Islamabad
Mandibular Angle Fracture, Surgical Approach &Amp; Incisions
Efficacy of Transoral Versus Transbuccal Technique for Fixation of Mandibular Angle Fracture
The goal of this clinical trial is to learn if transbuccal technique for mandibular angle fracture is better than transoral technique.
- Trial name
- NCT06622642
- Testing
- Transoral technique for mandibular angle fracture reduction, Transbuccal technique for mandibular angle fracture reduction
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Rate of Tooth Movement in Orthodontic Patients
Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial
it is a randomized control trial and aims at investigating the effects of PRF on rate of tooth movement and root length to be tested on larger sample size of pakistani population
- Trial name
- NCT06634017
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Knee Osteoarthritis
ADDITIVE BENEFITS of KALTENBORN SUSTAINED STRETCH JOINT MOBILIZATION with RESISTANCE EXERCISE TRAINING in KNEE OSTEOARTHRITIS
to determine the supplementary effects of Kaltenborn sustained stretch mobilization when combined with resistance training in the management of knee osteoarthritis.
- Trial name
- NCT06211387
- Testing
- Resistance Exercise Training, Joint Mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Foundation University Islamabad
Non-athletic Active Young Adults
Effect of Short Sprint Interval Training With Active Recovery as Compared to Passive Recovery on Anaerobic Capacity in Non-athletic Population
Short Sprint Interval Training (SSIT) is a modified form of Sprint Interval Training (SIT) defined as "small bouts of supramaximal exercise with recovery periods between them to increase peak oxygen uptake in spite of having a…
- Trial name
- NCT06625424
- Testing
- Short Sprint Interval Training with passive recovery, Short Sprint Interval Training with Active Recovery
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Type II Diabetes Mellitus
Feasibility Trial in Urban Pakistan for Community Engagement in Preventing Type II Diabetes and Risk Factors
This project aims to adapt, implement, and evaluate PLA based intervention in urban Karachi, Pakistan for TIIDM prevention and control.
- Trial name
- EMPOWER-D (NCT06570057)
- Testing
- Participatory, learning and Action (PLA) Based intervention
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Baqai Institute of Diabetology and Endocrinology
Community-acquired Pneumonia, Influenza, COVID-19
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients…
- Trial name
- REMAP-CAP (NCT02735707)
- Testing
- Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam
- Where
- 408 sites in United States, Australia and 27 more
- Volunteers
- 20,000 people
- Sponsor
- UMC Utrecht
Violence
Preventing Physical and Emotional Violence by Teachers in Public Schools in Pakistan
Violence has severe and long-lasting negative consequences for children and adolescents' well-being and psychosocial functioning, thereby also hampering communities and societies' economic growth.
- Trial name
- ICC-T_Pak (NCT06001554)
- Testing
- Interaction Competencies with Children - for Teachers (ICC-T)
- Where
- Pakistan
- Volunteers
- 2,100 people
- Sponsor
- Bielefeld University
Sickle Cell Disease, Thalassemia, Beta
Study of the Role of Genetic Modifiers in Hemoglobinopathies
This study will investigate the role of genetic modifiers in hemoglobinopathies through a large-scale, multi-ethnic genome-wide association study (GWAS).
- Conditions
- Sickle Cell Disease, Thalassemia, Beta, Thalassemia Alpha, Hemoglobinopathies
- Trial name
- INHERENT (NCT05799118)
- Testing
- GWAS
- Where
- 26 sites in United States, Angola and 14 more
- Volunteers
- 30,000 people
- Sponsor
- Cyprus Institute of Neurology and Genetics
Cardiovascular Diseases, Risk Factor, Cardiovascular
Prospective Urban Rural Epidemiology Study
To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g.
- Conditions
- Cardiovascular Diseases, Risk Factor, Cardiovascular, Health Behavior, Environmental Exposure
- Trial name
- PURE (NCT03225586)
- Where
- 34 sites in Argentina, Bangladesh and 23 more
- Volunteers
- 200,000 people
- Sponsor
- Population Health Research Institute
Cardiovascular Diseases in Pregnancy
Prospective Pakistan Registry of Echocardiographic Screening in Asymptomatic Pregnant Women
Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed.
- Trial name
- PRESAP (NCT06004544)
- Where
- Pakistan
- Volunteers
- 10,000 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Rheumatic Heart Disease
Screening and Secondary Prevention Rheumatic Heart Disease Study
After basic clinical screening including history and physical, Point of care ultrasound will be performed to look at Mitral, Aortic and Tricuspid Valves for regurgitation or stenosis.
- Trial name
- S2-RHD (NCT05991219)
- Where
- Pakistan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Diabetes Mellitus, Type 2, Diabetic Retinopathy
Exploring the Effectiveness of AI Generative Models for Diabetic Patients
We plan to explore the usability of Generative AI-Chatbot for Diabetic Patient
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Retinopathy, Diabetes
- Trial name
- NCT05883072
- Testing
- Exploring AI-Chatbot
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Pakistan Council of Scientific and Industrial Research
Atherosclerotic Plaque, Diabetes Mellitus, Type 2
Pakistan Study of Premature Coronary Atherosclerosis in Young Adults
Coronary heart disease (CHD) is a major cause of morbidity, disability, mortality, and health expenditures worldwide. A wealth of studies has demonstrated that people of South Asian ancestry have a higher risk of CHD and…
- Conditions
- Atherosclerotic Plaque, Diabetes Mellitus, Type 2, Hypertension, Stroke
- Trial name
- PAKSEHAT (NCT05156736)
- Where
- Pakistan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tabba Heart Institute
Hip Fractures
Audit of Hip Fractures Surgically Managed
Investigators are reviewing the the charts and medical records of participants who were operated at our institute from 2010 onward for hip fractures.
- Trial name
- NCT04187261
- Testing
- hip fracture surgeries
- Where
- Pakistan
- Volunteers
- 2,000 people
- Sponsor
- Aga Khan University