Clinical trials: in Qatar
Gene, Polymorphosis
Gene Polymorphisms and Morphine Analgesic Consumption
Variation of morphine requirements are seen considerably. Studies showed that pharmacogenetics (PGx) could possibly be used to tailor pain medication according to an individual's genetic background.
- Trial name
- NCT04621864
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
SARS-CoV-2 ICU Bound
Arterial Line Patency in ICU Bound COVID-19 Patients
The health care system was completely overwhelmed by the SARS-Cov-2 virus, and ICU admissions soared as a result of the ICU doctors' increased workload.
- Trial name
- NCT04992221
- Testing
- arterial line
- Where
- Qatar
- Volunteers
- 245 people
- Sponsor
- Hamad Medical Corporation
Coronavirus, COVID
Darunavir/Cobicistat vs. Lopinavir/Ritonavir in COVID-19 Pneumonia in Qatar
Coronavirus Disease 2019 (COVID-19) is a disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus.
- Conditions
- Coronavirus, COVID, Pneumonia
- Trial name
- DOLCI (NCT04425382)
- Testing
- Darunavir/Cobicistat, Lopinavir/Ritonavir
- Where
- Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
Covid19, Pneumonia
Anakinra in the Management of COVID-19 Infection
Coronavirus Disease 2019 (COVID-19) was first isolated in Wuhan, China in December 2019. It is rapidly spreading worldwide, posing a severe threat to global health.
- Conditions
- Covid19, Pneumonia, Cytokine Release Syndrome, Corona Virus Infection
- Trial name
- NCT04643678
- Testing
- Anakinra, Standard of Care
- Where
- Qatar
- Volunteers
- 80 people
- Sponsor
- Hamad Medical Corporation
Infection, Bacterial
Economic Evaluation of Vancomycin Therapeutic Drug Monitoring Methods
Vancomycin is a widely used antibiotic in the treatment of complicated gram positive infections. Approaches to vancomycin therapeutic drug monitioring (TDM) vary.
- Trial name
- NCT04297176
- Testing
- Vancomycin-traditional dosing, Vancomycin- Trough-only based dosing
- Where
- Qatar
- Volunteers
- 65 people
- Sponsor
- Hamad Medical Corporation
COVID-19 Patients, Hypoxemic Respiratory Failure
Awake Prone Positioning in COVID-19 Suspects With Hypoxemic Respiratory Failure
The investigator hypothesis is that early implementation of early, awake prone position for patients with COVID-19 pneumonia requiring oxygen therapy will reduce the need for escalation of respiratory support.
- Conditions
- COVID-19 Patients, Hypoxemic Respiratory Failure, Prone Position
- Trial name
- NCT04853979
- Testing
- PRONE POSITION
- Where
- Qatar
- Volunteers
- 61 people
- Sponsor
- Hamad Medical Corporation
Diabetes Mellitus, Hemodialysis Complication
Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility
A high prevalence of diabetes has been reported in Qatar with nearly 23% population suffering from the pandemic, thereby increasing the associated healthcare cost.
- Conditions
- Diabetes Mellitus, Hemodialysis Complication, Cardiovascular Complication, Quality of Life
- Trial name
- NCT05407207
- Testing
- Tennant Biomodulator ®
- Where
- 2 sites in United States, Qatar
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Hemodynamic Monitoring, ICU
Automated Inferior Vena Cava Collapsibility Index Fluid Responsiveness in Ventilated Patients After Cardiac Surgery.
Echocardiographic measurement of inferior vena cava (IVC) collapsibility index (CI) with automated software analyses has been introduced.
- Conditions
- Hemodynamic Monitoring, ICU, Cardiac Surgery
- Trial name
- NCT05283590
- Testing
- Automated echocardiographic inferior vena cava measurement
- Where
- Qatar
- Volunteers
- 50 people
- Sponsor
- Hamad Medical Corporation
COVID-19, Pregnant Women
Qatar PREgnancy Covid-19 OUtcome Study
The in-utero exposure of acute viral infection in some instances is proven to have short- and long-term neonatal effects during the postnatal and childhood period and the Zika virus, measles, mumps, and rubella are few examples.
- Trial name
- QPRECIOUS (NCT05349279)
- Where
- Qatar
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Inflammatory Markers Changes in Response to Extra-corporeal Membrane Oxygenator Decannulation
Inflammatory Markers Dynamics in Response to Extra-corporeal Membrane Oxygenator Decannulation
Extracorporeal membrane oxygenation (ECMO) aim at providing cardiac, respiratory support, or both. The use of ECMO could be associated with systemic inflammatory response syndrome (SIRS) at the time of initiation or the time of…
- Trial name
- ECMO (NCT04678518)
- Testing
- Inflammatory makers that will include Interleukins (IL); IL1, IL2, IL6 and TNF
- Where
- 2 sites in Qatar
- Volunteers
- 30 people
- Sponsor
- Hamad Medical Corporation
Procedural Pain
Comparing Buzzy Device With Emla Cream in Needle Related Pain
This randomized controlled study will enroll the eligible patients to either the Buzzy device arm or to the EMLA cream arm as a standard therapy. This will be done with concealment; however, blinding will not be practical.
- Trial name
- NCT05354739
- Testing
- The vibration cold device (BUZZY)
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
COVID-19, ARDS, Human
Inhaled Iloprost for Suspected COVID-19 Respiratory Failure
Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by the rapid onset of widespread inflammation in the lungs.
- Conditions
- COVID-19, ARDS, Human, Hypoxemic Respiratory Failure
- Trial name
- ILOCOVID (NCT04445246)
- Testing
- Inhaled ILOPROST
- Where
- Qatar
- Volunteers
- 40 people
- Sponsor
- Hamad Medical Corporation
Work Related Stress, Sense of Coherence
An Evaluation Study to Identify the Effectiveness of Clinical Supervision With Regards to Work-related Strain, Sense of Coherence, Increased Cultural Sensitivity and the Impact on Patient's Care: A Prospective Longitudinal Study in Mental Health Services in Qatar
Clinical supervision (CS) is a pragmatic approach, which enables nurses to work together; it can create a positive nursing environment, reduce stress, and increase clinical skills through peer support.
- Conditions
- Work Related Stress, Sense of Coherence, Cultural Sensitivity, Clinical Supervision
- Trial name
- NCT04196751
- Testing
- Clinical Supervision
- Where
- Qatar
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Preeclampsia, Preeclampsia Severe
Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial
This is an open label, randomized control trial (RCT) in which high risk for pre-eclampsia pregnant subjects will be randomly assigned to either an intervention group (metformin 1 gm twice daily plus aspirin 100 mg per day and…
- Conditions
- Preeclampsia, Preeclampsia Severe, High Risk Pregnancy, Eclampsia
- Trial name
- PREMET (NCT04855513)
- Testing
- Metformin
- Where
- Qatar
- Volunteers
- 414 people
- Sponsor
- Hamad Medical Corporation
Septic Shock, Critical Illness
Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock
Despite recent medical advances, sepsis and septic shock remain a major cause of death. Sepsis is a syndrome with a wide array of physiologic, pathologic, and biochemical abnormalities.
- Trial name
- HYVITS (NCT03380507)
- Testing
- Triple therapy group
- Where
- Qatar
- Volunteers
- 106 people
- Sponsor
- Hamad Medical Corporation
Burnout, Caregiver, Extracorporeal Membrane Oxygenation Complication
Impact of Extra Corporal Membrane Oxygenation Services on Burnout Development in Intensive Care Units.
The burnout phenomenon first came to clinical science 50 years ago. It is exponentially rising worldwide which prompted its discoverers to develop the most popular tool for its assessment, known as the Maslach burnout inventory…
- Conditions
- Burnout, Caregiver, Extracorporeal Membrane Oxygenation Complication, Intensive Care Unit
- Trial name
- burnout (NCT04620005)
- Testing
- Observational
- Where
- Qatar
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
COVID-19 Pneumonia
Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia.
Colchicine acts upstream in the cytokines cascade by inhibiting the NLRP3 inflammasome while IL-6 receptor antagonists (tocilizumab) block the end result of the cytokines cascade.
- Trial name
- NCT05118737
- Testing
- Colchicine
- Where
- Qatar
- Volunteers
- 230 people
- Sponsor
- Hamad Medical Corporation
COVID-19 Pneumonia, Extracorporeal Membrane Oxygenation Complication
Safety and Feasibility of Percutaneous Dilatational Tracheostomy in Patients With Severe COVID-19 Supported by ECMO
COVID-19 pandemic has presented the global health care systems with unprecedented and unexpected challenges. The clinical spectrum of COVID-19 disease varies from mild, at times asymptomatic, to severe life-threatening multiple…
- Conditions
- COVID-19 Pneumonia, Extracorporeal Membrane Oxygenation Complication, Tracheostomy Complication, Respiratory Failure
- Trial name
- NCT05045885
- Where
- Qatar
- Volunteers
- 32 people
- Sponsor
- Hamad Medical Corporation
Difficult or Failed Intubation, Obesity, Morbid
Evaluation of Preoperative Nasoendoscopy to Predict Difficult Intubation
Despite the availability of different methods for airway assessment, unexpectedly difficult intubations occur at a frequency of up to 15%.
- Trial name
- NCT05043779
- Testing
- Awake Airway Nasoendoscopy
- Where
- Qatar
- Volunteers
- 30 people
- Sponsor
- Hamad Medical Corporation
Ventilation Therapy; Complications, Trachea
Comparison Between VCV and FCV Through Ultra-thin Tube in Upper Airway Surgery
Ventilation through the small endotracheal tube is not an uncommon situation. The indications for it differ from elective upper airway surgery to emergency ventilation through needle cricothyrotomy.
- Trial name
- NCT05033730
- Testing
- Flow Controlled Ventilation
- Where
- Qatar
- Volunteers
- 30 people
- Sponsor
- Hamad Medical Corporation