Clinical trials: in Saudi Arabia
Neck Pain, Posterior
Radiofrequency Therapy for Chronic Neck Pain.
Background: Chronic neck pain (CNP) is a major health problem affecting individuals with high prevalence and subsequent complications which interfere with the physical, personnel, and psychological status.
- Trial name
- NCT05428254
- Testing
- Capacitive and Resistive Radiofrequency therapy, Exercise therapy
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Umm Al-Qura University
Dental Caries
Evaluation of the Chemo-mechanical Caries Removal Agent (BRIX3000®) in Primary Molars
Dental caries is one of the most prevalent chronic diseases in people worldwide. Traditional clinical treatment of dental decay has developed on the basis of the removal of carious tissues with high-speed handpieces and…
- Trial name
- NCT05427591
- Testing
- The chemomechanical caries removal agent "BRIX3000®" in group (1A), The traditional surgical treatment in group (1C), The chemomechanical caries removal agent "Carie-CareTM" in group (2B)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Hypothyroidism
Timing of Thyroxine Dose In Ramadan
A Randomized trial comparing two different timing of taking thyroxine in patients with Hypothyroidism during fasting the month of Ramadan.
- Trial name
- NCT05421468
- Testing
- L-Thyroxine time B (5-15 minutes Before dawn)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 250 people
- Sponsor
- King Abdullah International Medical Research Center
Type 2 Diabetes Mellitus
DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings
DISCOVER is a Non Interventional Study study to describe the disease management patterns and clinical evolution over three years in type 2 diabetes mellitus patients initiating a second line anti-diabetic treatment.
- Trial name
- DISCOVER (NCT02322762)
- Where
- 303 sites in Algeria, Argentina and 30 more
- Volunteers
- 15,992 people
- Sponsor
- AstraZeneca
Appendicitis, Pathology
Review of the Pathological Results of Appendectomy Specimens
This is a retrospective review study to evaluate the histopathological findings post appendectomy
- Conditions
- Appendicitis, Pathology, Acute Appendicitis, Appendicitis (Diagnosis)
- Trial name
- NCT05391269
- Where
- Saudi Arabia
- Volunteers
- 940 people
- Sponsor
- King Abdulaziz University
Health-Related Behavior
Behavioral Intervention to Promote Healthy Lifestyle Behaviors
in this study to "the investigators aim to improve lifestyle behaviors through behavioral interventions. Participants will be assigned to one of two groups.
- Trial name
- NCT05392218
- Testing
- motivational interviewing, general health education
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Thyroid Dysfunction, Hypothyroidism
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
The thyroid gland has been shown to be a common target for COVID 19 virus. Babies born to mothers positive for COVID 19 infections were noticed to have elevated thyroid stimulating hormone ( TSH ) levels on screening.
- Conditions
- Thyroid Dysfunction, Hypothyroidism, Hyperthyroidism
- Trial name
- COVID-19 (NCT05385029)
- Testing
- Thyroxine
- Where
- Saudi Arabia
- Volunteers
- 95 people
- Sponsor
- OMER B ABDELBASIT
Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic
A Study of Cusatuzumab in Combination With Azacitidine Compared With Azacitidine Alone in Patients With Higher-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) and Who Are Not Candidates for Hematopoietic Stem Cell Transplantation (HSCT)
The purpose of the study is to compare overall response rate (ORR) between treatment groups in participants with higher-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) who are not eligible for…
- Trial name
- NCT04264806
- Testing
- Azacitidine, Cusatuzumab
- Where
- 73 sites in Australia, Brazil and 9 more
- Sponsor
- Janssen Research & Development, LLC
Bacteremia Caused by Gram-Negative Bacteria
Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection
The purpose of this study is to determine whether ceftolozane-tazobactam is as effective as meropenem with respect to 30 day mortality in the treatment of bloodstream infection due to third-generation cephalosporin…
- Trial name
- MERINO III (NCT04238390)
- Testing
- Ceftolozane-Tazobactam, Meropenem
- Where
- 29 sites in Australia, Italy and 3 more
- Sponsor
- The University of Queensland
Dental Anxiety, Dental Pain
Pain Perception: on Relationships Between Dental Anxiety and Olfaction
the objective of this study is to evaluate the ability of olfaction in obtaining positive emotional and behavioral responses toward dental anxiety and pain in patients undergoing different dental procedures.
- Conditions
- Dental Anxiety, Dental Pain, Essential Oil
- Trial name
- NCT05369936
- Testing
- Aromatherapy
- Where
- Saudi Arabia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Qassim University
Anosmia, Ageusia
Investigating Anosmia and Ageusia in COVID-19 Adult Patients in Saudi Arabia
COVID-19 has adversely affected the healthcare system across the world. The world was not prepared for global outbreak of infectious diseases.
- Conditions
- Anosmia, Ageusia, Covid19, Corona Virus Infection
- Trial name
- NCT04388618
- Testing
- NHANES smell and taste tests
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 250 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Coronary Artery Disease, Obesity
Structured Physiotherapy Program in Obese and Non-obese Patients
A routine physiotherapy program has been shown to be effective in the prevention and treatment of cardiopulmonary diseases. It also significantly increases functional capacity following coronary artery bypass grafting.
- Trial name
- NCT05357937
- Testing
- standard physiotherapy program
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Covid 19 Positive, Corona Virus Infection
Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19
Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. At this time, there are no specific vaccines or treatments for COVID-19.
- Trial name
- NCT04387240
- Testing
- Artemisinin / Artesunate
- Where
- Saudi Arabia
- Sponsor
- Princess Nourah Bint Abdulrahman University
Cerebral Palsy
Effect of Transcutaneous Electrical Nerve Stimulation (TENS) on Spasticity in Adult Patients With Spastic Cerebral Palsy
Background: Cerebral palsy (CP) is a neurodevelopmental disorder caused by damage of the developing brain and marked by impairments such as increased muscle tone.
- Trial name
- NCT05352607
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Conventional physiotherapy treatment
- Where
- Saudi Arabia
- Volunteers
- 23 people
- Sponsor
- Reem Alharthi
Cerebral Palsy
Repetitive Split-Belt Treadmill Perturbation in Children With Unilateral Cerebral Palsy
This study was designed to investigate the effect of repeated split-belt treadmill waking practice on gait symmetry, dynamic balance control, and locomotor capacity in adolescents with unilateral cerebral palsy (ULCP).
- Trial name
- NCT05350241
- Testing
- Split-belt treadmill training, Standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Cairo University
Pediatric Obesity, COVID-19
Exercise and Diet for Pediatric Obesity
The coronavirus disease (COVID-19), is a communicable pandemic disease as stated by the world health organization (WHO), which has been affecting the world since December 2019.
- Trial name
- NCT05336006
- Testing
- High-intensity aerobic training with high protein diet, Control group
- Where
- Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Educational Problems
A Cross-over Randomised Trial Comparing Two Teaching Methods
The aim of the study aim to test the null hypothesis which states that there are no significant differences in knowledge retention and exam performance of dental undergraduate students in a Saudi Dental School using two different…
- Trial name
- NCT04692142
- Testing
- Flipped classroom teaching method
- Where
- Saudi Arabia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Diabetes
Twelve -Month Study Observing How Insulin-naïve Patients With Type 2 Diabetes Mellitus Manage Diabetes Using Toujeo® After Oral Antidiabetic Drug Failure, the Side Effect of Toujeo®, and The Cost.
Primary Objective: Assess effectiveness of insulin glargine (U300) in achieving glycemic goal measured by hemoglobin A1c (HbA1c).
- Trial name
- ATOS (NCT03703869)
- Testing
- Insulin glargine (U300)
- Where
- 388 sites in Colombia, Egypt and 16 more
- Volunteers
- 4,589 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
Evaluation of the Efficacy and Safety of Insulin Glargine 300 U/mL in Patients With Type 2 Diabetes Mellitus Uncontrolled on Other Kinds of Insulin
Primary Objective: To assess the efficacy of Gla-300 on glycemic control measured by hemoglobin A1c (HbA1c) change in patients with type 2 diabetes mellitus (T2DM) uncontrolled with their current basal insulin following the…
- Trial name
- ARTEMIS-DM (NCT03760991)
- Testing
- INSULIN GLARGINE (U300)
- Where
- 14 sites in Argentina, Colombia and 12 more
- Volunteers
- 372 people
- Sponsor
- Sanofi
Effect of Sleeve Gastrostomy in Both Cognition and Balance
Impact of Sleeve Gastrectomy on Balance and Cognitive Function
Purpose of the study: Purpose of study is to determine the effect of sleeve gastrectomy on balance and cognitive function in Saudi Arabia.
- Trial name
- NCT05337176
- Testing
- app-coo application
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Rawan Alwafi
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