Clinical trials: in Sri Lanka
Pregnant Woman With Premature Rupture of Amnion Membranes
A Comparison of Rapid Immunoassay Tests for the Detection of Ruptured Membranes
Specific objectives include analysis of performance of ROM Plus® in diagnosing ROM, as compared to Amnisure® and the conventional clinical assessment confirmed by a thorough chart review after delivery.
- Trial name
- NCT01668472
- Where
- Sri Lanka
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colombo
Necator Americanus Infection
Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections
Mebendazole tablets which are produced by most pharmaceutical manufacturers, including the State Pharmaceutical Manufacturing Corporation (SPMC) of Sri Lanka, contain a mixture of polymorphs A and C.
- Trial name
- NCT01350271
- Testing
- Mebendazole polymorph A and C 500 mg, Mebendazole polymorph C
- Where
- 2 sites in Sri Lanka
- Volunteers
- 214 people
- Sponsor
- University of Kelaniya
Rheumatoid Arthritis
A Clinical Trial to Study the Effects of Revamilast in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune and chronic inflammatory disease that causes progressive damage to joints of the body, affecting the functional capacity.
- Trial name
- TERRA (NCT01430507)
- Testing
- Revamilast
- Where
- 36 sites in India, Philippines and 3 more
- Volunteers
- 406 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Renal Insufficiency, Chronic
Renal Effects of an Angiotensin Converting Enzyme Inhibitor in Adults With Chronic Kidney Disease of Uncertain Aetiology
Enalapril would significantly reduce progression of renal disease in patients with Chronic Kidney Disease of Uncertain aetiology.
- Trial name
- CKDu (NCT01624064)
- Testing
- Enalapril, Calcium Supplement
- Where
- Sri Lanka
- Volunteers
- 200 people
- Sponsor
- Ministry of Health, Sri Lanka
Rheumatoid Arthritis
Dose Optimisation Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate
The purpose of this clinical trial is to establish what dose level and dosing frequency is optimal in the treatment of rheumatoid arthritis patients with ART621.
- Trial name
- NCT00854685
- Testing
- ART621
- Where
- Sri Lanka
- Volunteers
- 27 people
- Sponsor
- Arana Therapeutics Ltd
Lupus Erythematosus, Systemic, Lupus Nephritis
Study of LJP 394 in Lupus Patients With History of Renal Disease
The primary purpose of this study is to determine whether abetimus sodium is more effective than placebo in delaying time to renal flare in SLE patients with a history of renal disease.
- Trial name
- ASPEN (NCT00089804)
- Testing
- abetimus sodium (LJP 394), Phosphate-buffered saline
- Where
- 201 sites in United States, Argentina and 28 more
- Volunteers
- 943 people
- Sponsor
- La Jolla Pharmaceutical Company
Active Suicidal Ideations
Study to Prevent Negative Thoughts of Life
The purpose of the study is to test whether cognitive behaviour therapy (CBT) offered by trained therapists, to people with current active suicidal ideations, is efficacious as a secondary prevention strategy in Sri Lanka, when…
- Trial name
- NCT00862732
- Testing
- Cognitive behavioural therapy, Treatment as usual
- Where
- Sri Lanka
- Volunteers
- 68 people
- Sponsor
- Institute for Research & Development Sri Lanka
Snake Bites
Improving Safety of Antivenom in People Bitten by Snakes
A study to increase the safety of polyvalent antivenom involving 1000 patients in three centres: low dose adrenaline, promethazine, \& hydrocortisone (alone and in combination) to prevent acute adverse reactions to antivenom in…
- Trial name
- NCT00270777
- Testing
- adrenaline, promethazine, hydrocortisone
- Where
- Sri Lanka
- Volunteers
- 1,000 people
- Sponsor
- University of Kelaniya
Post-Traumatic Stress Disorders
KIDNET vs Meditation/Relaxation - a Dissemination Randomized Controlled Trial for the Treatment of Traumatized Children After War in Sri Lanka
The purpose of this study is to assess the efficacy of KIDNET versus a Meditation/Relaxation protocol in treating traumatized children when applied by locally trained teacher counsellors as well as the effectiveness and adequacy…
- Trial name
- NCT00564317
- Testing
- KIDNET, Meditation/Relaxation
- Where
- Sri Lanka
- Volunteers
- 48 people
- Sponsor
- University of Konstanz