Clinical trials: in Sweden
Hypertension, Pulmonary
A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16)
This is a Phase 2, double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of sotatercept versus placebo in adults with Cpc-PH due to HFpEF.
- Trial name
- CADENCE (NCT04945460)
- Testing
- Sotatercept 0.3 mg/kg, Sotatercept 0.3 mg/kg escalating to 0.7 mg/kg
- Where
- 119 sites in United States, Belgium and 10 more
- Volunteers
- 165 people
- Sponsor
- Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study
Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07292090
- Testing
- Intervention yogabased movements
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Terminal Illness
Family Talk Intervention in the Context of Specialised Palliative Home Care
This intervention study aims to evaluate a psychosocial family based intervention in clinical practice, the Family Talk Intervention (FTI), for families with dependent children affected by life-threatening/life-limiting illness…
- Trial name
- NCT05365919
- Testing
- Family Talk Intervention
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Ersta Sköndal University College
Illness Terminal
The Family Talk Intervention When a Parent With Dependent Children or a Child is Severely Ill
The overall aim of this study is to evaluate the effects and the implementation process of the Family Talk Intervention (FTI) in clinical practice when a child or a parent of dependent children has a…
- Trial name
- NCT05020158
- Testing
- Family Talk Intervention
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Ersta Sköndal University College
Mental Health Issue, Mental Disorder
A Trial of Two Universal Programs for Parents of Teenagers
Group-based and internet-delivered parenting programs may help parents improve their communication and relationships with their children.
- Conditions
- Mental Health Issue, Mental Disorder, Adolescent Behavior, Adolescent Development
- Trial name
- NCT06366438
- Testing
- ABC-teen, ParentWeb
- Where
- 58 sites in Sweden
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Kidney Cancer, Renal Cell Carcinoma Metastatic
Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma: The NORDIC-SUN-Trial
BACKGROUND: For synchronous metastatic renal cell carcinoma (RCC), surgical resection of the primary tumor in the presence of distant metastases has been the standard of therapy for select patients followed by systemic therapy.
- Conditions
- Kidney Cancer, Renal Cell Carcinoma Metastatic, Synchronous Neoplasm
- Trial name
- NORDIC-SUN (NCT03977571)
- Testing
- Cytoreductive nephrectomy, Tissue sampling
- Where
- 11 sites in Denmark, Finland and 2 more
- Volunteers
- 400 people
- Sponsor
- Niels Fristrup
Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis
A Study to Test Whether BI 1839100 Improves Cough in People With Idiopathic Pulmonary Fibrosis or Progressive Pulmonary Fibrosis
Adults 40 years of age and older with idiopathic pulmonary fibrosis (IPF) or 18 years and older with progressive pulmonary fibrosis (PPF) can participate in this study. Only people who have a chronic cough can take part.
- Trial name
- NCT06360094
- Testing
- BI 1839100
- Where
- 99 sites in United States, Australia and 22 more
- Volunteers
- 85 people
- Sponsor
- Boehringer Ingelheim
Abdominal Rectus Diastasis
Abdominal Rectus Diastasis Microscopy and Rehabilitation (AMIRE)
The goal of this randomised controlled trial is to evaluate the effect of a postoperative rehabilitation program after surgical correction of abdominal rectus diastasis. The main questions to answer are: 1.
- Trial name
- AMIRE (NCT06078085)
- Testing
- Postoperative rehabilitation program
- Where
- 4 sites in Sweden
- Volunteers
- 48 people
- Sponsor
- Umeå University
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD
Brief Summary: Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07348783
- Testing
- Intervention yoga based exercises
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
ADHD
A Comparison of Group Cognitive Behavioural Therapy (CBT) and Structured Activity Group for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Many adults with attention deficit hyperactivity disorder (ADHD) experience difficulties with inattention, planning, impulsivity and emotion regulation that impacts work and social life negatively also after treatment with…
- Trial name
- NCT07834437
- Testing
- Group CBT based on DBT-skills training, Activity group
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Stockholm
Gangliosidoses, GM2, Gangliosidosis, GM1
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis
An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of GM1 gangliosidosis or GM2…
- Trial name
- NCT07082543
- Testing
- AZ-3102
- Where
- 27 sites in United States, Argentina and 12 more
- Volunteers
- 75 people
- Sponsor
- Azafaros B.V.
Relapsing-remitting Multiple Sclerosis (RRMS)
Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)
The Main objectives of the study are to demonstrate pharmacokinetic (PK) similarity between ABP 692 and ocrelizumab (US), as well as between ABP 692 and ocrelizumab (EU).
- Trial name
- NCT06700343
- Testing
- Ocrelizumab (US), Ocrelizumab (EU), ABP 692
- Where
- 109 sites in United States, Belgium and 20 more
- Volunteers
- 152 people
- Sponsor
- Amgen
Depression Mild, Depression Moderate
iCBT for Seniors With Depression in Primary Care
This clinical trial aims to evaluate the potential benefits of internet cognitive behavioural therapy (iCBT) for elderly patients with mild/moderate depression and compare its effectiveness with the current treatment as usual…
- Trial name
- NCT06537869
- Testing
- iCBT for depression
- Where
- Sweden
- Volunteers
- 390 people
- Sponsor
- Göteborg University
Hemophilia A
A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health
This is a 48-month observational, prospective, multicentre study. The overall aim of the study is to evaluate the long-term effectiveness of Elocta treatment on joint health in patients treated prophylactically with Elocta in a…
- Trial name
- A-MORE (NCT04293523)
- Testing
- ELOCTA
- Where
- 53 sites in Czechia, Estonia and 12 more
- Volunteers
- 427 people
- Sponsor
- Swedish Orphan Biovitrum
Menopause Syndrome, Sleep Disturbance
Exercise as Medicine: A Non-Pharmacological Approach to Menopausal Symptoms
The aim of this clinical trial is to evaluate the effects of different forms of physical exercise in women experiencing menopausal symptoms.
- Trial name
- NCT07351006
- Testing
- Strength training, Dance-based training
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Linnaeus University
Asthma
Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma
This is a parallel-group, Phase 2, randomized, double-blind, placebo-controlled, 2-arm study for the treatment of asthma. The purpose of this study is to assess the efficacy, safety, and tolerability of add-on therapy with…
- Trial name
- AIRLYMPUS (NCT06676319)
- Testing
- Lunsekimig, Short-Acting Beta Agonists (SABA), Fluticasone/Salmeterol
- Where
- 221 sites in United States, Argentina and 20 more
- Volunteers
- 556 people
- Sponsor
- Sanofi
Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2
A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy
AML and MDS-EB2 are malignancies of the bone marrow. The standard treatment for these diseases is chemotherapy. Patients participating have a special type of this disease because the leukemia cells (blasts) have developed an…
- Trial name
- HOVON150AML (NCT03839771)
- Testing
- AG-120, AG-221
- Where
- 181 sites in Australia, Austria and 13 more
- Volunteers
- 968 people
- Sponsor
- Stichting Hemato-Oncologie voor Volwassenen Nederland
Mental Disorder, Mental Health Issue
A Comparison of Two Ultra-brief Interventions in Primary Care for Patients With Anxiety, Depression, and Stress.
This pilot randomized controlled trial evaluated the feasibility of a Swedish translation of an Acceptance and Commitment Therapy protocol targeting repetitive negative thinking (RNT-ACT) compared with therapist-supported…
- Conditions
- Mental Disorder, Mental Health Issue, Mental Depression, Anxiety
- Trial name
- RNTACTSweden (NCT05946382)
- Testing
- RNT-ACT Protocol, iCBT Treatment
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Unresectable Pancreatic Cancer
Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.
This will a be an open label, multicentre, randomized, controlled study in patients with unresectable pancreatic cancer, locally advanced or metastatic, with significant weight loss, and the tumour located in the head of the…
- Trial name
- PERTseverance (NCT06099119)
- Testing
- creon 35.000 Ph.U (R), Best Standarard of Care
- Where
- 4 sites in Italy, Spain and 1 more
- Volunteers
- 100 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Attention Deficit Hyperactivity Disorder (ADHD)
A Comparison of Group Cognitive Behavioural Therapy (CBT) and Structured Activity Group for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Many adults with attention deficit hyperactivity disorder (ADHD) experience difficulties with inattention, planning and impulsivity that impacts work and social life negatively also after treatment with medication.
- Trial name
- NCT06604845
- Testing
- Group cognitive behavioural therapy (CBT), Activity group
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Vastra Gotaland Region
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