Clinical trials: in Syria
Relapsing Remitting Multiple Sclerosis (RRMS)
Observational Study to Analyse the Impact of Nurse Support and Disease Related Factors on Long- Term Adherence to Betaferon Treatment
The Study analyses the influence of selected factors on adherence to Betaferon treatment in patients with early multiple sclerosis (MS).
- Trial name
- BEACON (NCT00787657)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 36 sites in Argentina, Bahrain and 34 more
- Volunteers
- 1,723 people
- Sponsor
- Bayer
Broken Down Molars, IPS-emmax Crowns
Evaluation of a New Design of Crowns in the Posterior Teeth
Background: no randomized controlled trial has tried to compare treatment outcomes between the IPS.emmax endocrowns and the IPS.emmax conventional crowns .
- Trial name
- NCT02110550
- Testing
- IPS.emmax endocrown
- Where
- 2 sites in Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Class II Dental Restorations
Evaluation of Two Different Methods of Resin Composite Application In Class II Restorations
Three clinical groups will be evaluated. Each group of patients will undergo one method of Resin Composite application (multi-layer technique 'control group' - bulk-fill Technique - Sonicfill technique).
- Trial name
- NCT02185573
- Testing
- Bulk fill, SonicFill
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Defected Interdental Papilla
Reconstruction of Interdental Papilla Using Hyaluronic Acid
Objective and background: The aim of this study is to evaluate the clinical outcome of using the hyaluronic acid gel in reconstructing inter-dental papillae at the aesthetic zones in a follow-up period of six months.
- Trial name
- NCT02119741
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Mandibular Distal-extension Prostheses
Management of Loading Forces Distribution in Mandibular Distal-extension Prostheses
The two structures that support a mandibular distal extension removable partial denture differ markedly in their visco-elastic response to loading.
- Trial name
- NCT02178384
- Testing
- Altered cast technique, Precision Attachments, Resilient layer
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Chronic Periodontitis
Relationship Between Chronic Periodontitis and Vitamin D and Calcium in Men
Objective: The objective was to evaluate whether serum vitamin D and calcium concentrations are associated with chronic periodontitis in Syrian men Methods: This study designed as "Matched Case-Control Study".200 males will be…
- Trial name
- NCT02127346
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Damascus University
Chronic Periodontitis, Aggressive Periodontitis
Nitro-oxidative Stress in Periodontitis
Periodontitis is a chronic inflammatory disease whose etio-pathogencity is not fully understood yet. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are involved in physiological and pathological processes.
- Trial name
- NCT02127203
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Complete Mandibular Dentures With Poor Retention
Evaluation of Three Hard Relining Materials in Complete Dentures
Purpose: The purpose of this study is to evaluate three hard relining materials after 3 and 6 months of use with mandibular complete dentures.
- Trial name
- NCT02203279
- Testing
- Rebase II Fast, Flexacryl, Vertex
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Osteoporosis
Bisphosphonates Effects On Alveolar Bone Among Osteoporotic Women
Osteoporosis is a public health problem. It is a skeletal disease being treated by Bisphosphonates as the first choice medication.
- Trial name
- NCT02115490
- Testing
- Bisphosphonates
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Patients With Dental Extraction
Role of Hyaluronic Acid in Bone Healing After Dental Extraction
This is a randomized controlled trial with a split mouth design. Patients with an indication of lower dental extraction will be asked to join this research project at the Department of Oral and Maxillofacial Surgery at University…
- Trial name
- NCT02330822
- Testing
- Hyaluronic Acid
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Damascus University
Orthodontic Patients Requiring Canine Retraction
The Use of a Modified Dentoalveolar Distractor to Retract Maxillary Canines
In this study, two distractors will be used to retract maxillary canines into the extraction sites. The first distractor is a modified Hyrax expander with two arms soldered to two bands connected to a canine and a molar; and the…
- Trial name
- NCT02332421
- Testing
- modified dentoalveolar distractor
- Where
- Syria
- Volunteers
- 8 people
- Sponsor
- Damascus University
Hepatitis C, Chronic
A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C
This multicenter study will evaluate the correlation of interleukin 28B (IL28B) genotypes with disease characteristics and demographics in treatment-naïve and treatment-experienced chronic hepatitis C patients, including patients…
- Trial name
- NCT01675427
- Testing
- Interleukin 28B testing
- Where
- 210 sites in United States, Argentina and 29 more
- Volunteers
- 4,766 people
- Sponsor
- Hoffmann-La Roche
Class III Malocclusion in Growing Patients
Changes Following the Treatment of Lower Jaw Protrusion Using Two Appliances
An in vivo study evaluating the efficacy of the Tandem appliance in the treatment of maxillary deficiency in growing patients compared to the conventional facemask appliance treatment.
- Trial name
- NCT02144324
- Testing
- Tandem Appliance
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Infant's Tooth Brushing
Impact of Providing Free Preventive Dental Health Products on Infant's Tooth Brushing and Bottle-feeding Termination Practices
Governmental initiatives (such as Sure Start in the UK) have integrated an oral health promotion intervention within their maternal and child health program and delivered dental education and enabling resources (a gift bag…
- Trial name
- NCT02200536
- Testing
- Infant oral health promotion package, Infant oral health pamphlet
- Where
- Syria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Damascus University
Benign Radiolucent Lesions
Diagnostic Accuracy of Ultrasonography in Detecting Benign Radiolucent Lesions
This is an in vivo study which aims to evaluate the diagnostic accuracy of ultrasonography in detecting benign radiolucent lesion in the both jaws.
- Trial name
- NCT02121236
- Where
- Syria
- Volunteers
- 25 people
- Sponsor
- Damascus University
Class II Division 1 Malocclusion
Mechanism of Class II Correction With Fixed Lingual Mandibular Growth Modificator (FLMGM)
The aim of the current controlled trial was to assess the possible net skeletal and dental effects of FLMGM treatment in relation to growth with emphasis on the contribution of skeletal and dental changes to sagittal correction…
- Trial name
- FLMGM (NCT01853995)
- Testing
- Fixed Lingual Mandibular Growth Modificator (FLMGM)
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Damascus University
Idiopathic Menorrhagia
MiCo - Mirena or Conventional Medical Treatment for Menorrhagia
The aim of this prospective, non-interventional post-marketing surveillance study is to obtain data on safety and efficacy of Mirena in treatment of heavy menstrual bleeding (Menorrhagia) under daily-life treatment conditions.For…
- Trial name
- NCT01085487
- Testing
- Levonorgestrel (Mirena, BAY86-5028), Hormonal treatment, Antifibrinolytic treatment
- Where
- 14 sites in Albania, Bosnia and Herzegovina and 12 more
- Volunteers
- 1,211 people
- Sponsor
- Bayer
Beta-thalassemia Major, Hemosiderosis
Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration)
To allow patients treated with deferasirox in the core study to continue iron chelation therapy for 2 years or until the drug became locally commercially available.
- Conditions
- Beta-thalassemia Major, Hemosiderosis, Iron Overload, Rare Anemia
- Trial name
- ESCALATOR (NCT00171301)
- Testing
- Deferasirox
- Where
- 5 sites in Egypt, Lebanon and 3 more
- Volunteers
- 233 people
- Sponsor
- Novartis Pharmaceuticals
Smoking Cessation
Waterpipe Cessation Intervention Study
The study is a two-group parallel arm randomized clinical trial, to be conducted at the Syrian Center for Tobacco Studies (SCTS) in Aleppo, Syria.
- Trial name
- NCT01135173
- Testing
- Waterpipe smoking cessation
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- University of Memphis
Smoking Cessation
Nicotine Patch Trial in Syrian Primary Care Settings
The study is a two-arm, parallel group, randomized, placebo-controlled, double blind trial, conducted at four primary health care centers in Aleppo, Syria, to test the efficacy of transdermal nicotine patch therapy vs.
- Trial name
- NCT01085032
- Testing
- Transdermal Nicotine
- Where
- Syria
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- University of Memphis