Clinical trials: in Uruguay
CIN3, CIN2
Cervical Cancer Screening With Human Papillomavirus Testing
HPV testing for primary cervical cancer screening of women over 30 years of age is likely to become the standard of care in the near future in many areas of the world.
- Conditions
- CIN3, CIN2, Cervical Cancer
- Trial name
- ESTAMPA (NCT01881659)
- Testing
- HPV screening
- Where
- 12 sites in Argentina, Bolivia and 7 more
- Volunteers
- 50,000 people
- Sponsor
- International Agency for Research on Cancer
Myofascial Pain, Craniofacial Pain
Effect of Acupuncture on Craniomandibular Pain of Myofascial Origin.
Myofascial pain is one of the most prevalent conditions within temporomandibular disorders. Despite its high prevalence, health systems pay insufficient attention to it.
- Trial name
- NCT05414695
- Testing
- real acupuncture
- Where
- Uruguay
- Volunteers
- 60 people
- Sponsor
- Universidad de la Republica
Fresh Sockets With Buccal Resorption
Immediate Dentoalveolar Restoration Compared to Bio-oss
This randomised controlled trial compares the immediate dentoalveolar restoration and bovine demineralised bone in immediate implants placed in fresh sockets with buccal resorption.
- Trial name
- IDRBio-oss (NCT03202030)
- Testing
- Immediate dentoalveolar restoration, Demineralized bovine bone
- Where
- Uruguay
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Point of Care Ultrasound
Impact of a Multisystemic Ultrasound Protocol in Patients of Polyvalent Intensive Care Units
Ultrasound is a widely used tool for clinicians to manage severe acute patients, seeking to improve the limitations of traditional physical examination and special studies that require patient transfers and can be harmful.
- Trial name
- NCT03608202
- Testing
- POCUS protocol group, Control group
- Where
- Uruguay
- Volunteers
- 80 people
- Sponsor
- Asociacion Española Primera en Salud
Aortic Valve Stenosis, Aortic Valve Disease
Anticoagulation for Aortic Bioprosthesis (ANTIPRO)
This study evaluates the clinical and hemodynamic outcome in patients after aortic valve replacement. Half of the patients will receive warfarin + aspirin and the other half will receive only aspirin.
- Conditions
- Aortic Valve Stenosis, Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Valve Regurgitation
- Trial name
- NCT03807921
- Testing
- Warfarin, Aspirin
- Where
- 2 sites in Uruguay
- Volunteers
- 140 people
- Sponsor
- Instituto Nacional de Cirugia Cardiaca, Uruguay
Aortic Aneurysm, Abdominal
Endurant Stent Graft Natural Selection Global Postmarket Registry
The purpose of ENGAGE is to prospectively collect global 'real world' data on the Endurant Stent Graft System from AAA subjects.
- Trial name
- ENGAGE (NCT00870051)
- Testing
- Endurant Stent Graft
- Where
- 80 sites in Argentina, Australia and 28 more
- Volunteers
- 1,266 people
- Sponsor
- Medtronic Cardiovascular
COVID-19 Pandemic, Preterm
Socioeconomic Inequalities Exacerbated by Mitigation Measures to COVID-19 and Differences in Prematurity Prevalence
Objective: to assess the perinatal results in Uruguay during the semester of successful control of the COVID 19 pandemic to evaluate the impact of the crises in the public and private sub sectors of the Health System.
- Conditions
- COVID-19 Pandemic, Preterm, Low Birth-weight
- Trial name
- NCT05087160
- Testing
- mitigation measures against COVID 19
- Where
- Uruguay
- Volunteers
- 37,323 people
- Sponsor
- Universidad de la Republica
Sinus Node Dysfunction
Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)
Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)
- Trial name
- IMPROVE Brady (NCT01643707)
- Testing
- Evidence based guidelines and tools
- Where
- 21 sites in Argentina, Bangladesh and 5 more
- Volunteers
- 1,342 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
End Stage Liver Disease, Rejection
Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients
To search for suitable pharmacodynamic biomarkers, i.e., with high specificity for calcineurin inhibition and most affected by inter-individual variability, our works aimed at exploring the pharmacodynamics of CNI, the strength…
- Conditions
- End Stage Liver Disease, Rejection, Infection, Malignancy
- Trial name
- 3PIGREF (NCT01760356)
- Where
- Uruguay
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- UDA Centro Nacional Hepato-Bilio-Pancreático
Breast Neoplasms
A Safety and Tolerability Study of Assisted and Self-Administered Subcutaneous (SC) Herceptin (Trastuzumab) as Adjuvant Therapy in Early Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
This multicenter, two-cohort, non-randomized, open-label study will evaluate the safety and tolerability of assisted and self-administered SC Herceptin as adjuvant therapy in participants with early HER2-positive breast cancer…
- Trial name
- SafeHER (NCT01566721)
- Testing
- Herceptin
- Where
- 437 sites in Albania, Algeria and 57 more
- Volunteers
- 2,577 people
- Sponsor
- Hoffmann-La Roche
Sedentary Behavior, Mental Health Wellness 1
Influence Physical Activity Psychological Responses COVID-19 Pandemic
The on-going Wuhan coronavirus (COVID-19) outbreak has become the world's leading health headline and is causing major panic and public concerns.
- Trial name
- NCT04352517
- Testing
- Online Survey
- Where
- 3 sites in Brazil, Chile and 1 more
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Von Willebrand Disease
Surveillance of Safety and Efficacy of Wilate in Patients With Von Willebrand Disease
This is an observational study, hence there is no study hypothesis
- Trial name
- NCT01602419
- Testing
- Patients using Wilate as standard of care
- Where
- 24 sites in United States, Argentina and 8 more
- Volunteers
- 120 people
- Sponsor
- Octapharma
Non-small-cell Lung Cancer (NSCLC)
A Study to Reveal the Patient Characteristics and Treatment Patterns of Stage III Non-small-cell Lung Cancer Patients
This large multinational, non-interventional study (NIS), will retrospectively collect data derived from established medical records over a period of up to approximately 6 years (2013 to 2018), building a platform to capture and…
- Trial name
- KINDLE (NCT03725475)
- Where
- 32 sites in Argentina, Chile and 8 more
- Volunteers
- 3,111 people
- Sponsor
- AstraZeneca
Breast Cancer
Molecular Profiling of Stage II and III Breast Cancer in Latin American Women Receiving Standard-of-Care Treatment
Background: Researchers want to learn more about breast cancer in Latin American women. They also want to learn how and why women respond differently to standard treatment.
- Trial name
- NCT02326857
- Where
- 9 sites in Argentina, Brazil and 3 more
- Volunteers
- 1,334 people
- Sponsor
- National Cancer Institute (NCI)
Breast Neoplasms
A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast Cancer
This multicenter, open-label, single-arm, Phase IIIb study will evaluate the safety and tolerability of pertuzumab in combination with trastuzumab (Herceptin) and a taxane (docetaxel, paclitaxel or nab-paclitaxel) in first-line…
- Trial name
- PERUSE (NCT01572038)
- Testing
- Docetaxel, Nab-paclitaxel, Paclitaxel
- Where
- 299 sites in Algeria, Argentina and 37 more
- Volunteers
- 1,436 people
- Sponsor
- Hoffmann-La Roche
Hip Fractures
Latin America Hip Fracture Mortality Study
The purpose of this study is to estimate the survival proportion one year after surgery for intertrochanteric fracture in older adults in Latin America.
- Trial name
- LAMOS (NCT01650064)
- Where
- 16 sites in Argentina, Brazil and 6 more
- Volunteers
- 168 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Diet Habit, Weight, Body
Eating and Physical Activity Patterns of the Population Working in the Uruguayan State Electrical Company.
Stuydy of eatin and physical activity patterns in Uruguayan workers and association with obesity, overweight, and tasks.
- Trial name
- PAF (NCT04509908)
- Where
- Uruguay
- Volunteers
- 1,964 people, healthy volunteers welcome
- Sponsor
- Administración Nacional de Usinas y Transmisiones Eléctricas
Fetal Alcohol Syndrome
Prenatal Alcohol Biomarker Study in Uruguay
The purpose of this study is to examine the association between maternal alcohol use and newborn phosphatidylethanol (PEth) levels in their newborn.
- Trial name
- NCT02600624
- Where
- 2 sites in United States, Uruguay
- Volunteers
- 1,412 people
- Sponsor
- Northwestern University
Protein Deregulation, Blood Pressure
Urinary Proteomics Combined With Home Blood Pressure Telemonitoring for Health Care Reform
UPRIGHT-HTM will compare risk stratification, treatment efficiency and health economic outcomes of a diagnostic approach based on home blood pressure telemonitoring combined with urinary proteomic profiling with home blood…
- Conditions
- Protein Deregulation, Blood Pressure, Health Care Utilization, Cost Effectiveness
- Trial name
- UPRIGHT-HTM (NCT04299529)
- Testing
- In-vitro urinary diagnostic test
- Where
- 12 sites in Belgium, Denmark and 7 more
- Volunteers
- 1,000 people
- Sponsor
- KU Leuven
Lymphoma, Non-Hodgkin
BBR 2778 for Relapsed, Aggressive Non-Hodgkin's Lymphoma (NHL)
BBR 2778 is a novel aza-anthracenedione that has activity in experimental tumors and shows reduced potential for cardiotoxicity in animal models.
- Trial name
- NCT00088530
- Testing
- pixantrone, cyclophosphamide, vincristine, rituximab, prednisone, Vinorelbine, Oxalplatin, Ifosfasmide, Etoposide, Mitoxatrone, Gemcitabine or Rituximab
- Where
- 99 sites in United States, Argentina and 18 more
- Volunteers
- 140 people
- Sponsor
- CTI BioPharma