Clinical trials: Pregabalin
- Drug or intervention Pregabalin
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Healthy
An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following Various Sized Lunches As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release tablet following a 400 to 500 calorie, 600 to 750 calorie, or 800 to 1000 calorie medium-fat lunch as…
- Trial name
- NCT01270815
- Testing
- Pregabalin controlled release, 330 mg, 400 to 500 calories, Pregabalin controlled release, 330 mg, 600 to 750 calories, Pregabalin controlled release, 330 mg, 800 to 1000 calories
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of A Controlled Release Pregabalin Tablet As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule
The purpose of this study is to 1)evaluate the extent of absorption of multiple doses of a pregabalin controlled release tablet as compared to multiple doses of the pregabalin immediate release capsule, 2) evaluate the…
- Trial name
- NCT01202435
- Testing
- Pregabalin controlled release, 82.5 mg, Pregabalin immediate release, 25 mg
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
An Investigation of the Absorption and Pharmacokinetics of Multiple Doses of Three Controlled Release Pregabalin Tablets as Compared to Multiple Doses of the Immediate Release Pregabalin Capsule
The purpose of this study is to 1) evaluate the extent of absorption of multiple doses of three pregabalin controlled release tablets as compared to multiple doses of the pregabalin immediate release capsule, 2) evaluate the…
- Trial name
- NCT01009541
- Testing
- Pregabalin controlled release, 82.5 mg, Pregabalin controlled release, 165 mg, Pregabalin controlled release, 330 mg
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy Lactating Women
A Study Of Pregabalin (Lyrica) Drug Levels In Urine, Plasma And Breast Milk Of Healthy Lactating Women
This is a pharmacokinetic study to determine the safety and tolerability of pregabalin in healthy lactating women. The objectives are to determine whether pregabalin is secreted in breast milk and if so, to characterize…
- Trial name
- NCT01727791
- Testing
- pregabalin (Lyrica)
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
Non-interaction Study Between Pregabalin and Tramadol, Administered Individually or Combination, in Healthy Subjects
The study was carried out in the Clinical Unit and Analytical Unit of the Department of Pharmacology and Toxicology of the Faculty of Medicine of the Universidad Autónoma de Nuevo León, with the aim of comparing the…
- Trial name
- NCT05389150
- Testing
- Fixed dose combination Pregabalin 150 mg / Tramadol 50 mg, Pregabalin 150mg, Tramadol 50 mg
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Healthy Male and Female Subjects
Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy Participants
The primary goal of this clinical trial is to compare pharmacokinetic characteristics of Y-4 tablets with pregabalin capsules and riluzole tablets in the US healthy adult participants after single oral administration under fasted…
- Trial name
- NCT07618715
- Testing
- Y-4 tablet, Pregabalin capsule, Riluzole tablet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Healthy
PK Study of Pregabalin GLARS Tablet 150mg and IR Formulation After Multiple Dosing Under Fed Condition in Healthy Male Subjects
The purpose of this clinical trial is to compare the pharmacokinetic characteristics of GLA5PR GLARS tablet 150mg and Lyrica Capsule 75mg. GLA5PR GLARS tablet 150mg is a New Formulation which is made by GL Pharm Tech.
- Trial name
- GLA5PR-102 (NCT01638273)
- Testing
- Pregabalin 150mg, Pregabalin 75mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Neuropathic Pain
The Pharmacokinetics of GLA5PR Tablet According to the Renal Function
To evauate pharmacokinetics of GLA5PR tablet according to the renal function
- Trial name
- NCT03963362
- Testing
- GLA5PR tablet 75 mg, GLA5PR tablet 150 mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Neuropathic Pain
Efficacy and Safety of Pregabalin/Tramadol Combination Versus Pregabalin in Acute Pain of Neuropathic Origin
Phase IIIb confirmatory study of efficacy and safety, longitudinal, multicenter, randomized, double-blind study of the combination Pregabalin/Tramadol versus Pregabalin in the management of acute pain of neuropathic origin.
- Trial name
- LOBUXALIII (NCT05324059)
- Testing
- Pregabalin 75mg/ Tramadol 50 mg, Pregabalin 75mg
- Where
- Mexico
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Peripheral Neuropathy Pain
PK and Food Effect of Pregabalin Study After Dosing in Healthy Male Volunteers
This study is to assess the pharmacokinetics of Pregabalin controlled release formulation after multiple dosing as compared to Pregabalin immediate release formulation and the food effect of high fat diet after single dosing in…
- Trial name
- NCT02783638
- Testing
- YHD1119, Lyrica
- Where
- South Korea
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Healthy
A Study To Assess The Pharmacokinetics, Safety, And Tolerability Of A Pregabalin Controlled Release Formulation Administered Following Various Sized Caloric Meals As Compared To The Pregabalin Immediate Release Formulation
The purpose of this study is to (1) evaluate the effect of caloric intake on the pharmacokinetics of a single dose of a 330 mg pregabalin controlled release tablet relative to a 300 mg pregabalin immediate release capsule…
- Trial name
- NCT01080612
- Testing
- 330 mg pregabalin controlled release, 300 mg pregabalin immediate release
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
Drug-Drug Interaction Study of "CG-651" in Healthy Volunteer
This is randomized , open-label, multiple-dose, parallel study to compare the pharmacokinetics and to evaluate Drug-Drug Interaction of "CG-651" in healthy volunteers.
- Trial name
- NCT05370716
- Testing
- Polmacoxib, Pregabalin
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- CrystalGenomics, Inc.
Dental Pain
Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
Accessing the efficacy and safety of pregabalin when used alone and in combo with acetaminophen in a dental pain model. To test whether pre-operative dose of pregabalin increases the time to significant post-operative pain (NRS ≥…
- Trial name
- NVK009-0001 (NCT03652818)
- Testing
- Pre-Op pregabalin, Post-Op pregabalin
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Postoperative Pain
A Phase 1 Study to Evaluate Pregabalin and Acetaminophen in Healthy Volunteers
This is a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to determine a maximum tolerated dose of IV PGB and to evaluate the safety, tolerability, and PK of an admixture of IV PGB…
- Trial name
- NCT04265456
- Testing
- Pregabalin 100mg, Acetaminophen 1300mg
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Healthy
An Investigation of the Effects of Erythromycin on the Pharmacokinetics of the Pregabalin Controlled Release Tablet
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release tablet with and without coadministration of erythromycin and 2) evaluate the safety and tolerability of a…
- Trial name
- NCT01342198
- Testing
- Pregabalin controlled release, 330 mg, erythromycin
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
Pharmacokinetic Drug Interaction Between Pregabalin and Thioctic Acid.
A randomized, open-label, six-sequence, three-period, three-treatment, multiple dosing clinical trial to investigate the pharmacokinetic drug interaction between Pregabalin and Thioctic acid after oral administration in healthy…
- Trial name
- NCT01808300
- Testing
- Pregabalin 300mg, Thioctic acid 600mg
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Unimed Pharmaceuticals
Abuse Potential
Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users
This is a Phase 4 clinical study in healthy non-drug dependent recreational opioid users to assess the abuse potential of Lyrica when taken alone or in combination with oxycodone.
- Trial name
- NCT05053126
- Testing
- Pregabalin 300mg, pregabalin 450 mg, Pregabalin 300 mg with oxycodone 20 mg
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Viatris Specialty LLC
Healthy
Bioequivalence Study of Two Formulations of Pregabalin Capsules 150 mg
The present study was conducted to find out whether the bioavailability of 150 mg pregabalin capsules produced by Dexa Medica was equivalent to the reference products (Lyrica® capsule 150 mg, Pfizer Manufacturing Deutschland…
- Trial name
- NCT02233777
- Testing
- Pregabalin capsules 150 mg of Dexa Medica, Pregabalin capsules 150 mg of Pfizer Manufacturing Deutschland
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dexa Medica Group
Healthy
Assessment of the Analgesic Effects of PF-05089771 and Pregabalin in Healthy Volunteers Using Evoked Pain Endpoints
This study will examine the activity of PF-05089771 and pregabalin, alone and in combination on a panel of evoked pain tests carried out from 0.5 to 10 hours following oral dosing in healthy male subjects
- Trial name
- NCT02349607
- Testing
- PF-05089771 300mg, PF-05089771 300 mg + pregabalin 300 mg, pregabalin 300 mg
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following A Low, Medium, And High-Fat Evening Meal As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release tablet following either a low, medium, or high-fat evening meal as compared to a single dose of the…
- Trial name
- NCT01257529
- Testing
- Pregabalin controlled release, 330 mg, low-fat, Pregabalin controlled release, 330 mg, medium-fat, Pregabalin controlled release, 330 mg, high-fat
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.