Clinical trials: Probiotic
- Drug or intervention Probiotic
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Antibiotic-Associated Diarrhea, Clostridium Difficile-Associated Diarrhea
Efficacy and Safety Study in the Prevention of Antibiotic-Associated Diarrhea (AAD) and Clostridium Difficile-Associated Diarrhea (CDAD) in Hospitalized Adult Patients Exposed to Nosocomial Infection
The purpose of this study is to evaluate the efficacy and safety of Bio-K+ CL-1285 in the prevention of Antibiotic-Associated Diarrhea (AAD) and Clostridum difficile-Associated Diarrhea (CDAD) in hospitalized patients exposed to…
- Trial name
- NCT00958308
- Testing
- BIO-K+ CL-1285®
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Bio-K Plus International Inc.
Obesity, Intra-Abdominal Fat
Effect of a Probiotic on Visceral Fat Accumulation
The study's main objective is to investigate if an extract containing the probiotic Bifidobacterium animalis subsp. lactis BPL1 (CECT 8145) has a positive effect on the accumulation of abdominal visceral fat in people with…
- Conditions
- Obesity, Intra-Abdominal Fat, Subcutaneous Fat, Abdominal
- Trial name
- BIFFAT (NCT02921217)
- Testing
- Active Probiotic, Inactivated probiotic, Control
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Photobiology
Placebo-controlled Assessment of the Effect of a Food Supplement on Skin Protection After Exposure to UV Radiation
A probiotic bacterial strain was tested in a randomized, double blind , placebo controlled clinical trial with 54 healthy male volunteers.
- Trial name
- NCT00351689
- Testing
- dietary supplement
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Constipation
Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects
The objective of this study is to evaluate if consumption of fermented milk containing Lactobacillus casei strain Shirota has an impact on stool consistency, stool frequency, constipation-related symptoms, and quality of life in…
- Trial name
- NCT01375712
- Testing
- Fermented milk containing Lactobacillus casei strain Shirota
- Where
- Germany
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Yakult Honsha Co., LTD
Moderate Gastrointestinal Discomfort
Investigating the Effectiveness of 2 Different Doses of BIOHM FX Probiotic Blend in Improving Digestive Symptoms
The rationale for this study is to observe the effect of two different doses of a consumer-grade probiotic product called FX Probiotic Blend on digestive symptoms in individuals with moderate gastrointestinal discomfort.
- Trial name
- NCT06782945
- Testing
- BIOHM FX Probiotic Blend
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Biohm Technologies
Breast Milk Expression
Effect of Consuming a Combination of Probiotic Strains and a Combination of Plant Extracts and a Probiotic Strain on the Production and Nutritional Composition of Breast Milk
The objective of this trial is to evaluate the effect of the consumption of a combination of probiotic strains (Prob-milk) and of a combination of plant extracts plus an inactivated probiotic strain (VoluntasProb) on the…
- Trial name
- NCT04639232
- Testing
- Prob-milk, Voluntas-Prob
- Where
- Spain
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Healthy
Detection of Probiotic Strains in Vaginal Swabs Collected From Healthy Women
The aim of this trial is to detect the presence of various probiotic strains in vaginal swabs of healthy women orally consuming a probiotic supplement for 4 weeks.
- Trial name
- VSS (NCT04719611)
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Acne Vulgaris, Acneiform Eruptions
The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne
The purpose of this study is to evaluates how probiotics and dietary supplementation with an herbal powder can shift the gut microbiome in those with non-cystic acne vulgaris.
- Conditions
- Acne Vulgaris, Acneiform Eruptions, Skin Diseases, Sebaceous Gland Diseases
- Trial name
- NCT05919810
- Testing
- Probiotic, Oral herbal powder supplement
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Microbial Colonization
Microbial Colonization of Dairy Free Oral Probiotics
The aim of this study is to evaluate the colonization efficacy of probiotic lozenges containing dairy and dairy free probiotic Streptococcus salivarius M18, in healthy adults
- Trial name
- NCT05375396
- Testing
- Streptococcus salivarius M18 lozenges, Streptococcus salivarius M18 dairy free lozenges
- Where
- New Zealand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- John Hale
Disbiosis, Abdominal Pain
Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects.
A randomized, double-blind, placebo-controlled, cross-over trial performed at one centre in Italy to explore the ability of a multistrain probiotic mixture, to modulate markers of inflammation and intestinal barrier function and…
- Conditions
- Disbiosis, Abdominal Pain, Constipation, Diarrhea
- Trial name
- NCT03234452
- Testing
- Lactoflorene plus
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefarmaco OTC SpA
Infant Development, Gut Microbiome
Characterisation of the Gut Microbiota in Term Infants After Maternal Supplementation of Probiotics
A monocenter, open label pilot study in pregnant women and their offspring with at least four weeks prenatal and four weeks postnatal maternal intervention with a study product consisting of four different food constituents.
- Trial name
- NCT04987593
- Testing
- Probiotics
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Intestinal and Immune Function Improved
The Effect of Probiotics on the Improvement of Intestinal and Immune Function
Evaluate the effectiveness and safety of Lactobacillus delbrueckii subsp. bulgaricus LB42 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06873438
- Testing
- Probiotic group
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Microbial Colonization
Microbial Colonization of Oral Probiotics
The aim of this study is to evaluate the colonization efficacy of probiotic lozenges and powders containing specific prebiotics in healthy adults
- Trial name
- NCT05375383
- Testing
- Streptococcus salivarius K12 lozenge, Probiotic S. salivarius K12 lozenges containing prebiotic A, Probiotic S. salivarius K12 lozenges containing prebiotic B
- Where
- New Zealand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BLIS Technologies Limited
Growth
The Effects on Growth of a Non-Routine Infant Formula
A study to evaluate the growth and development of term infants fed either an extensively hydrolyzed formula with probiotics, a partially hydrolyzed formula with probiotics, or an extensively hydrolyzed formula without probiotics
- Trial name
- NCT00655720
- Testing
- infant formula
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Irritable Bowel Syndrome
Effect of Probiotic Supplement in Alleviating Functional Gastrointestinal Symptoms
The purpose of this study is to analyse the effect of a probiotic supplement on functional intestinal symptoms among subjects diagnosed with irritable bowel syndrome (IBS).
- Trial name
- NCT01728610
- Testing
- Probiotic (Active high), Probiotic (Active low)
- Where
- 2 sites in Finland
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Danisco
Gastrointestinal Diseases
Probiotics Improve Health Young Volunteers' Gut Microbiota
The goal of this clinical trial is to evaluate whether daily supplementation with the probiotic Bifidobacterium breve BBr60 can improve metabolic, gastrointestinal, and emotional health in healthy adult volunteers aged 19 to 45…
- Trial name
- NCT06196892
- Testing
- Probiotic BBr60
- Where
- China
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Skin Problems
Efficacy Evaluation of the Probiotics Containing Skincare Products on Skin
Previous studies on skin health with Lactic acid bacteria (LAB) have been published for many years, including prevention of skin diseases and improvement of skin conditions.
- Trial name
- NCT03350893
- Testing
- Emulsion base with probiotics, Emulsion base
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GenMont Biotech Incorporation
Constipation, Dyspepsia
Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System
The purpose of this study is to determine whether Yili "Chang Qing" Pro-ABB yoghurt is effective in improving mild constipation and the intestinal micro-ecology environment \& alimentation.
- Conditions
- Constipation, Dyspepsia, Flatulence, Abdominal Pain
- Trial name
- NCT01682798
- Testing
- Yili "Chang Qing" Pro-ABB yoghurt (Formula 1), Yili "Chang Qing" Pro-ABB yoghurt (Formula 2)
- Where
- 2 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Mild to Moderate Levels of Stress
Psychophysiological Effects of Probiotic Supplementation
This is a pilot exploratory study to investigate the effects of a probiotic Bifidobacterium longum NCC3001 intake on physiological and psychophysiological parameters related to stress in healthy individuals with mild to moderate…
- Trial name
- NCT05226520
- Testing
- Experimental probiotic product
- Where
- Switzerland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy Response to Probiotics
Defining the Normal Human Response to Probiotics
The study is a mono-center, randomized, semi-blinded, placebo-controlled, cross-over, proof-of principle study in healthy volunteers. The study will determine the probiotic effect of LGG on intestinal tissue and intestinal cells
- Trial name
- NCT03140878
- Testing
- LGG
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chr Hansen