Clinical trials: Lidocaine
Nasolabial Folds
Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose
Safety study that compares Perlane to Perlane with Lidocaine while correcting wrinkles in the area around your nose.
- Trial name
- NCT00823069
- Testing
- Perlane and Perlane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medicis Global Service Corporation
Infraorbital Hollowing
A Study to Evaluate the Safety and Effectiveness of Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
A Multicenter, Evaluator-blinded, Randomized, No-treatment Controlled Study to Evaluate the Safety and Effectiveness of MAILI PRECISE With Lidocaine Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
- Trial name
- NCT06394076
- Testing
- Cross-linked sodium hyaluronate gel for injection containing lidocaine
- Where
- China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Sinclair Pharmaceuticals Limited
Dermatological Non-Disease
Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Clinical Investigation to demonstrate the effectiveness and safety of Princess Filler Lidocaine in the correction of moderate to severe nasolabial folds
- Trial name
- FILIDO (NCT03990883)
- Testing
- Princess Filler Lidocaine
- Where
- 11 sites in United States
- Volunteers
- 295 people
- Sponsor
- Croma-Pharma GmbH
Healthy
Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers
The main objective of the study is to determine the safety and tolerability of repeated application of PSD502 to the glans penis in healthy male volunteers
- Trial name
- NCT00483990
- Testing
- PSD502
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Aged Skin
An Efficacy and Safety Study Evaluating Treatment Sessions of Restylane Skinboosters Vital Lidocaine in the Face
A randomised, multi-centre, parallel-group efficacy and safety study evaluating two and three initial treatment sessions of Restylane Skinboosters Vital Lidocaine in the face.
- Trial name
- NCT02403986
- Testing
- Restylane Vital Skinboosters Lidocaine
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- Galderma R&D
Mid Face Volume Deficit
Clinical Investigation for Evaluating the Safety and Efficacy of JTM102 to Mid Face Volume Deficiency
This study is clinical investigation for evaluating safety and efficacy of JTM102 on temporary correction of mid-face volume deficiency
- Trial name
- NCT07265778
- Testing
- JTM102, Juvederm VOLUMA with Lidocaine
- Where
- South Korea
- Volunteers
- 149 people
- Sponsor
- Jetema Co., Ltd.
Diabetic Neuropathic Pain
A Randomized, Double-blind, Placebo- and Active-controlled Study of the Electric Current Effects of ABT-639 on the Spontaneous Activity of Pain Sensory Receptors in Patients With Diabetic Peripheral Neuropathy
People with diabetes can, over time develop nerve damage throughout the body with symptoms such as pain, tingling, or numbness (loss of feeling) in the hands, arms, feet and legs.
- Trial name
- NCT01589432
- Testing
- ABT-639, Lidocaine
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Cheek Volume Augmentation
A Prospective, Multicenter, Randomized, Comparator-controlled, Evaluator-blinded Study to Evaluate the Safety and Effectiveness of VP1 Lido US for Volume Augmentation of the Cheek
The primary objective of the study is to demonstrate non-inferiority of VP1 Lido US versus an approved hyaluronic acid dermal filler following deep (subdermal and/or supraperiosteal) injection of the cheek for volume augmentation.
- Trial name
- BCheek (NCT04886232)
- Testing
- VP1 Lido US, Restylane Lyft Lidocaine
- Where
- 10 sites in Germany
- Volunteers
- 202 people
- Sponsor
- Merz North America, Inc.
Healthy Volunteers
Tolerability, Safety and Pharmacokinetics of Four Formulations of Ketorolac Tromethamine in Healthy Volunteers
This was a phase 1, double-blind, 4-way crossover study in healthy male and female volunteers. Subjects received 4 formulations of intranasal ketorolac tromethamine 30 mg.
- Trial name
- NCT01355588
- Testing
- Ketorolac Tromethamine, Ketorolac Tromethamine with 4% Lidocaine hydrochloride (HCl), Ketorolac Tromethamine with 5% Lidocaine HCl
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Egalet Ltd
Hyperhidrosis
Feasibility Study: Ulthera® System for the Treatment of Axillary Hyperhidrosis
Single-center, randomized, split-body, pilot study, treatment of up to 23 subjects in two treatment groups. Subjects will receive two Ultherapy treatments at Day 0 with follow-ups at 7 and 14 days post-treatment #1, and Day 28…
- Trial name
- NCT01713959
- Testing
- Ulthera System treatment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ulthera, Inc
Osteoarthritis, Knee
Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee
Patients with unilateral or bilateral osteoarthritis (OA) of the knee participated in a Phase II clinical trial to assess the efficacy of lidocaine 5% patch compared with placebo in the treatment of pain from OA of the knee.
- Trial name
- NCT00904462
- Testing
- Lidoderm
- Where
- 24 sites in United States
- Volunteers
- 224 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Infraorbital Hollowing
Study to Assess Effectiveness and Adverse Events of JUVEDERM VOLBELLA With Lidocaine Injection in Correcting Infraorbital Hollowing in Chinese Adult Participants
Aged appearance is often caused by an infraorbital hollowing, which is characterized as a sunken appearance of the eye that results in the casting of a dark shadow over the nasal lower eyelid, giving a fatigued appearance.
- Trial name
- NCT05088980
- Testing
- VOLBELLA with Lidocaine
- Where
- 7 sites in China
- Volunteers
- 160 people
- Sponsor
- Allergan
Shoulder Impingement Syndrome
Study Evaluating Heated Lidocaine/Tetracaine Topical Patch in Treatment of Patients With Shoulder Impingement Syndrome
The purpose of the study is to explore the potential usefulness of a heated lidocaine 70 mg/tetracaine 70 mg topical patch for the treatment of pain associated with shoulder impingement syndrome
- Trial name
- NCT01055444
- Testing
- Heated lidocaine and tetracaine topical patch
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ZARS Pharma Inc.
Pain, Aging
RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT06378086
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Temporal Hollowing
Effectiveness and Safety of Restylane Contour in the Treatment of Temple Hollowing
This is a randomized, no-treatment-controlled, evaluator-blinded, multi-center study to evaluate the effectiveness and safety of Restylane® Contour in correction of temple hollowing.
- Trial name
- NCT05691972
- Testing
- Restylane Contour
- Where
- 15 sites in United States
- Volunteers
- 225 people
- Sponsor
- Galderma R&D
Wrinkles
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial Fold Injection
The objective of this study was to evaluate the efficacy and safety of HA IDF II plus (with lidocaine) injected in the nasolabial fold compared to HA IDF II (without lidocaine).
- Trial name
- NCT02340078
- Testing
- HA IDF II plus, HA IDF II
- Volunteers
- 62 people
- Sponsor
- LG Life Sciences
Postsurgical Pain
Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty
Total knee arthroplasty is a surgical treatment which involves replacing the damaged articular cartilage of the knee joint with an artificial prosthetic in end-stage knee osteoarthritis.
- Trial name
- MP-TKA (NCT06202989)
- Testing
- Multiprofen-CC™ plus standard treatment
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- KAZM Pharmaceuticals Inc.
Marionette Lines Forehead Contouring
VFORM: Prospective, Open Label, Study to Evaluate VOLIFT With Lidocaine Treatment for FORehead Contouring and Marionette Lines
To collect post-marketing data on Juvéderm® VOLIFT™ with Lidocaine on the following indications: 1. Marionette lines (treatment skin depressions) 2. Forehead contouring (face contouring)
- Trial name
- VFORM (NCT05077488)
- Testing
- Juvéderm® VOLIFT™ with Lidocaine
- Where
- France
- Volunteers
- 163 people
- Sponsor
- Allergan
Uterine Fibroids, Polyps
Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System
The purpose of this study is to develop a recommended local anesthetic protocol and post-treatment pain management regimen, in order to assure patient comfort during office-based treatment with the MyoSure Hysteroscopic Tissue…
- Trial name
- NCT00979342
- Testing
- Hysteroscopic Morcellator
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Hologic, Inc.
Facial Wrinkles
A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to compare subject comfort during and after injection with NADGL and Captique® Injectable Gel, in the nasolabial folds.
- Trial name
- NCT00417469
- Testing
- NADGL
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Genzyme, a Sanofi Company