Clinical trials: Sildenafil
Erectile Dysfunction
A Multicenter, Open Label, To Evaluate The Efficacy And Satisfaction Of Patrex® In Men With Erectile Dysfunction.
A multicenter open label study to assess the efficacy of sildenafil rapid dose titration to 100 mg in men with erectile dysfunction, based on the Erectile Function (EF) domain score of the International Index of Erectile Function…
- Trial name
- NCT00468650
- Testing
- sildenafil citrate
- Where
- 9 sites in Mexico
- Volunteers
- 117 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Given With Or Without Food.
This study will evaluate if an orally disintegrating tablet of sildenafil will have similar pharmacokinetic properties when given with food and without food.
- Trial name
- NCT01254396
- Testing
- Sildenafil
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy Males
Study Of Bioavailability Of Two Sildenafil 100mg Oral Tablet Formulations
the pharmacokinetics of sildenafil following single doses of sildenafil CT administered with and without water is similar relative to the conventional oral tablet of sildenafil administered with water.
- Trial name
- NCT00902512
- Testing
- Treatment A, Blood samples for the analysis of sildenafil in plasma, Treatment B
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Quality of Erection Study
The study objective is to evaluate the effect that sildenafil citrate has on the hardness of erections in males with erectile dysfunction, based on subject responses to question 5 on the Event Log (hardness of erection) as…
- Trial name
- NCT00159900
- Testing
- Sildenafil Citrate
- Where
- 23 sites in Brazil, Germany and 3 more
- Volunteers
- 300 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Premature Ejaculation
A Phase 2 Study of On-demand Therapy With Clomipramine and Sildenafil Combination in Premature Ejaculation
The purpose of this study is to evaluate the safety and efficacy of on-demand therapy with CDFR0812-15/25mg and CDFR0812-15/50mg compared to on-demand therapy with single-drug administration of Clomipramine HCl 15mg in Korean…
- Trial name
- NCT02571101
- Testing
- CDFR0812-15/25mg, CDFR0812-15/50mg, Condencia
- Where
- 9 sites in South Korea
- Volunteers
- 297 people
- Sponsor
- CTC Bio, Inc.
Meniere's Disease
Sildenafil For Meniere's Disease
Meniere's disease affects a person's sense of balance. An attack can last 20 minutes to 2 hours or longer. Symptoms include rotational vertigo, hearing loss, tinnitus and a sensation of fullness in the affected ear and may be…
- Trial name
- NCT00145483
- Testing
- Sildenafil
- Where
- 4 sites in Australia
- Volunteers
- 163 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Phase 2 Efficacy Study of Sildenafil Products in Adult Men With Erectile Dysfunction
The goal of this clinical trial is to learn how different sildenafil-based erectile dysfunction (ED) treatments affect erectile function in adult men.
- Trial name
- NCT07231185
- Testing
- Hezkue, Hezkue Turbo, Galotam
- Volunteers
- 200 people
- Sponsor
- Aspargo Labs, Inc
Obesity
The Effect Of NS-0200 and NS-0300 Versus Placebo on Weight In Obesity
This is a 24-week study to evaluate the effects of two fixed-dose combinations of leucine and sildenafil or two fixed-dose combinations of leucine, sildenafil and metformin compared to placebo.
- Trial name
- NCT03364335
- Testing
- Leu Sil 1.0mg, Leu Sil 4.0mg, Leu Met Sil 1.0mg
- Where
- 15 sites in United States
- Volunteers
- 267 people
- Sponsor
- NuSirt Biopharma
Impotence
Studying the Preference of Tadalafil to Sildenafil in Men With Problems Getting an Erection Across Nations
Study to determine if men from around the world prefer sildenafil to tadalafil.
- Trial name
- NCT00547287
- Testing
- tadalafil, sildenafil
- Where
- Brazil
- Volunteers
- 2,760 people
- Sponsor
- Eli Lilly and Company
Pulmonary Hypertension
Study to Assess the Longterm Safety of Sildenafil Citrate in Patients With Pulmonary Arterial Hypertension
Open label extension study to the pivotal efficacy study to assess the safety of sildenafil citrate in patients with pulmonary arterial hypertension
- Trial name
- NCT00159887
- Testing
- Sildenafil citrate
- Where
- 65 sites in United States, Australia and 20 more
- Volunteers
- 260 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
A Study for Patients With Erectile Dysfunction to Test Whether Tadalafil Taken Once a Day Can Better Improve Psychological Outcomes.
The primary purpose of the study is to help answer whether tadalafil taken once a day can help improve the psychological outcomes (such as sexual self confidence, spontaneity and time concerns) compared to sildenafil taken as…
- Trial name
- NCT00734604
- Testing
- tadalafil once a day [T(OaD)], sildenafil citrate as needed [S(PRN)], tadalafil as needed [T(PRN)]
- Where
- 37 sites in United States, Australia and 7 more
- Volunteers
- 378 people
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction
Study to Investigate Effect of a New Drug (PF-00446687) in Males Suffering From Erectile Dysfunction
The purpose of this study is to investigate the effect of up to 200 mg of PF-00446687 on erectile activity in males suffering from erectile dysfunction as well as examining the safety and toleration of the drug.
- Trial name
- NCT00862888
- Testing
- PF-00446687, Sildenafil
- Where
- 3 sites in Norway, United Kingdom
- Volunteers
- 39 people
- Sponsor
- Pfizer
Pulmonary Arterial Hypertension
Open Label Access Study Of Sildenafil In Adult Patients With Pulmonary Arterial Hypertension Completing A1481244 Study
In an earlier study, sildenafil citrate administered to patients of PAH led to improvement in pulmonary arterial pressure, cardiac output, quality of life, and other parameters as compared to placebo.
- Trial name
- UK 92480 (NCT00878943)
- Testing
- Sildenafil citrate
- Where
- 5 sites in India
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Phase 2a Topical Sildenafil Proof-of-Concept Study in Men With Mild to Moderate ED
This is a Phase 2a, single-dose, double-blind, placebo-controlled, 2-way crossover study in men with ED. A single 2 gram dose of SST-6006 topical cream 5% w/w (formulated to deliver 100 mg of sildenafil) or a topical placebo…
- Trial name
- NCT02390960
- Testing
- Sildenafil Cream, Penile Plethysmography (RigiScan)
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Strategic Science & Technologies, LLC
Impotence
A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses
The primary aim of this study is to assess how effective PF-00592379 is in restoring penile erections in patients with erectile dysfunction.
- Trial name
- NCT00273416
- Testing
- PF-00592379, Sildenafil 100mg
- Where
- 2 sites in Norway, United Kingdom
- Volunteers
- 32 people
- Sponsor
- Pfizer
Pulmonary Hypertension
Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.
Pulmonary Arterial Hypertension (PAH) is a severe progressive disease with a high mortality. Although several drugs are available for the treatment of PAH none offer a cure, therefore there is still a high medical need for new…
- Trial name
- PATENT PLUS (NCT01179334)
- Testing
- Riociguat (Adempas, BAY63-2521), Sildenafil
- Where
- 25 sites in United States, Austria and 7 more
- Volunteers
- 18 people
- Sponsor
- Bayer
Erectile Dysfunctions, Healthy Volunteer
A Study to Assess the Safety, Tolerability and Pharmacokinetics of Viaca (Sildenafil + Cabergoline) Compared With Sildenafil and Cabergoline
This is a Phase 1, open-label, single-ascending-dose study evaluating the safety, tolerability, and pharmacokinetics (PK) of Viaca - a fixed-dose oral combination of sildenafil (a PDE5 inhibitor) and cabergoline (a dopamine D2…
- Trial name
- NCT07732387
- Testing
- Viaca, Sildenafil 50 mg, Cabergoline 0.5 MG
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yanping Kong
Healthy Volunteers
Bioavailability of 3 Sildenafil Oral Disintegrating Tablet Formulations Compared to the Standard Oral Tablet
The bioavailability of the oral disintegrating tablet formulations given without water will be similar to an equivalent dose of the standard oral tablet given with water.
- Trial name
- NCT00950404
- Testing
- Viagra 50 mg tablet, Formulation B ODT tablet 50 mg, Formulation C ODT tablet 50 mg
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Microvascular Coronary Artery Disease
Pharmacodynamic Study to Assess the Effects of Repeated Dosing of SAR247799 on Endothelial Function in Patients With Type 2 Diabetes Mellitus
Primary Objective: To assess the pharmacodynamic effects of SAR247799 on macrovascular endothelial function of the brachial artery using flow-mediated dilation (FMD) in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT03462017
- Testing
- SAR247799, Sildenafil, Acetylcholine
- Where
- 2 sites in Germany
- Volunteers
- 54 people
- Sponsor
- Sanofi
Pulmonary Arterial Hypertension, Hypertension, Pulmonary
Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a rare, progressive, and life-threatening disease. In many patients, the course of PAH is a steady deterioration and reduced life expectancy.
- Trial name
- NCT01642407
- Testing
- Sildenafil
- Where
- 5 sites in Japan
- Volunteers
- 6 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.