Clinical trials: sponsored by Alcon Research
Ametropia, Myopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses
The primary objective of this study is to evaluate the axis orientation of LID226397 toric contact lenses.
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT05959200
- Testing
- Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of DAILIES TOTAL1® spherical soft contact lenses over approximately 1 week of daily wear.
- Trial name
- NCT06044948
- Testing
- Delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Bullous Keratopathy, Corneal Erosion
Air Optix® Night and Day® Aqua Therapeutic Wear
The purpose of this study is to support the safety and performance assessment of Air Optix Night and Day Aqua (AONDA) soft contact lenses for therapeutic use in accordance with updated EU Medical Device Regulation (MDR)…
- Conditions
- Bullous Keratopathy, Corneal Erosion, Entropion, Corneal Edema
- Trial name
- NCT05956535
- Testing
- Lotrafilcon A contact lenses, Balafilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 168 people
- Sponsor
- Alcon Research
Cataract, Aphakia
Clareon Toric vs Eyhance Toric
The primary purpose of this study is to compare the Clareon/Clareon Toric Intraocular Lenses (IOLs) to the Eyhance/Eyhance Toric IOLs in binocular Best Corrected Distance Visual Acuity (BCDVA) at 3 months postoperative.
- Trial name
- NCT05481125
- Testing
- Clareon IOL, Clareon Toric IOL, Eyhance IOL
- Where
- 8 sites in United States
- Volunteers
- 203 people
- Sponsor
- Alcon Research
Dry Eye
Systane® Hydration PF and Systane® Hydration Preserved
The purpose of this post-market clinical follow-up (PMCF) study is to assess the performance and safety of Systane Hydration Preservative Free (PF) in subjects experiencing dry eye symptoms (Group 1) and in contact lens (CL)…
- Trial name
- NCT05932238
- Testing
- Polyethylene glycol 400 and propylene glycol solution/drops - Preservative Free (PF), Polyethylene glycol 400 and propylene glycol solution/drops - Preserved
- Where
- 3 sites in Canada
- Volunteers
- 137 people
- Sponsor
- Alcon Research
Refractive Errors
Air Optix® Night and Day® Aqua Continuous Wear
The purpose of this retrospective, Post-Market Clinical Follow-Up (PMCF) study is to assess the long term performance and safety of Air Optix® Night and Day® Aqua (AONDA) contact lenses in a real-world setting when worn as 30…
- Trial name
- NCT05992675
- Testing
- Lotrafilcon A contact lenses, Balafilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 1,256 people
- Sponsor
- Alcon Research
Hyperopia, Hyperopic Astigmatism
Clinical Investigation of the WaveLight® EX500 Excimer Laser
The purpose of this study is to collect efficacy and safety data on the WaveLight EX500 excimer laser system for the correction of hyperopia with and without astigmatism by laser in situ keratomileusis (LASIK) treatment.
- Trial name
- NCT04805593
- Testing
- WaveLight EX500 excimer laser system, LASIK
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Alcon Research
Refractive Errors
Air Optix Daily Wear Contact Lenses
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix Aqua, Air Optix plus HydraGlyde Sphere, and Air Optix plus HydraGlyde Toric soft contact lenses in a…
- Trial name
- NCT05827224
- Testing
- Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive
- Where
- 5 sites in United States
- Volunteers
- 312 people
- Sponsor
- Alcon Research
Glaucoma
EX-PRESS® P-50 and EX-PRESS® P-200
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term clinical performance and safety outcomes for EX-PRESS Glaucoma Filtration Devices Models P-50 and P-200.
- Trial name
- NCT06119178
- Testing
- EX-PRESS P-50 filtration device, EX-PRESS P-200 filtration device
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Air Optix® Night and Day® Aqua Daily Wear
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix® Night and Day® Aqua (AONDA) contact lenses in a real-world setting when worn as daily wear for vision…
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT05976750
- Testing
- Lotrafilcon A contact lenses, Balafilcon A contact lenses
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses
The purpose of this study is to assess the overall clinical performance of a contact lens made with a modified manufacturing process.
- Trial name
- NCT05725317
- Testing
- LID220365 contact lens, LID006961 contact lens
- Where
- 7 sites in United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Refractive Errors, Presbyopia
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this clinical trial is to assess on-eye performance and overall fit of an investigational multifocal toric contact lens to aid in confirmation of the study lens design.
- Conditions
- Refractive Errors, Presbyopia, Astigmatism
- Trial name
- NCT05886907
- Testing
- Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Visual Acuity
Post-Market Study of Alcon Intraocular Lenses
The purpose of the study is to evaluate clinical and functional performance in real-world conditions in participants who have been implanted with Acrysof IQ Vivity (Extended Vision) IOLs compared with Alcon Aspheric Monofocal…
- Trial name
- NCT05414565
- Testing
- Vivity IOL, Aspheric monofocal IOL
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Primary Open Angle Glaucoma, Cataract
Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent
The purpose of this study is to assess long-term (10 years post-CyPass implantation) status of the corneal endothelium in subjects who were implanted with the CyPass Micro-Stent in the COMPASS trial.
- Trial name
- COMPASS XXT (NCT04629521)
- Testing
- CyPass Micro-Stent, Cataract Surgery
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Refractive Ametropia
Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens
The purpose of this clinical trial was to evaluate the clinical performance of a manufacturing process on a frequent replacement multifocal contact lens.
- Trial name
- NCT05765227
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Presbyopia
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The purpose of this clinical trial is to assess the clinical performance of LID223194 Multifocal (MF) contact lenses and commercially available Air Optix plus HydraGlyde (AOHG) MF contact lenses.
- Trial name
- NCT05702541
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Alcon Research
Primary Open-angle Glaucoma, Cataract
Post Approval Study of the CyPass System
The purpose of this study is to demonstrate that the rate of clinically relevant complications associated with CyPass Micro-Stent placement and stability using the CyPass 241-S applier, as determined at 36 months in the…
- Trial name
- NCT03273907
- Testing
- CyPass Micro-Stent implanted with CyPass 241-S applier, Cataract surgery
- Where
- 20 sites in United States
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Primary Open Angle Glaucoma (POAG)
A Study to Assess Long-Term Safety of the CyPass Micro-Stent in Patients Completing the COMPASS Trial
The purpose of this study is to evaluate the long-term safety of the CyPass Micro-Stent in subjects who completed Study Protocol TMI-09-01, COMPASS Trial.
- Trial name
- COMPASS-XT (NCT02700984)
- Testing
- CyPass Micro-Stent, Cataract Surgery
- Where
- 22 sites in United States
- Volunteers
- 282 people
- Sponsor
- Alcon Research
Angle-closure Glaucoma
Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG)
The purpose of this study is to demonstrate that the Intraocular Pressure (IOP) lowering efficacy of Travoprost Ophthalmic Solution 0.004% is superior to that of Pilocarpine 1% in patients with chronic angle-closure glaucoma…
- Trial name
- NCT00762645
- Testing
- Travoprost 0.004% (Travatan), Pilocarpine 1%
- Volunteers
- 30 people
- Sponsor
- Alcon Research