Clinical trials: sponsored by University of Manchester
Heart Failure
Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk
This study will evaluate the Heartfelt device, a novel, passive monitoring system that detects early signs of fluid build-up in patients (oedema) with heart failure by measuring changes in foot and lower leg volume through…
- Trial name
- ME-HF (NCT07067658)
- Testing
- Installation of Heartfelt Device, Enhanced Standard care, Questionnaires
- Where
- 18 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Heartfelt Technologies
Lung Cancer
Lung Cancer Indicator Detection
The Lung Cancer Indicator Detection (LuCID) study investigates the the diagnostic accuracy of FAIMS for diagnosis of lung cancer by analysis of exhaled Volatile Organic Compounds.
- Trial name
- LuCID (NCT02612532)
- Testing
- ReCIVA breath sampler
- Where
- 17 sites in Belgium, Germany and 2 more
- Volunteers
- 2,603 people
- Sponsor
- Owlstone Ltd
Acute Respiratory Tract Infection
Differentiation of Upper and Lower Respiratory Tract Infections Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate upper and lower respiratory tract infections (URTI and LRTI)
- Trial name
- NCT05175612
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 400 people
- Sponsor
- Healthy Networks
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Schizophrenia
A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males
A Phase 1, Single-centre, Double-blind, Placebo controlled Crossover Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Male Participants
- Trial name
- NCT02935725
- Testing
- Low dose AUT00206 800mg, High dose AUT00206 2000 mg, Ketamine
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Autifony Therapeutics Limited
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
- Trial name
- NCT00708643
- Testing
- Habitual Silicone Hydrogel Contact Lens, narafilcon A
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Comparison of Two Daily Disposable Contact Lenses
This study seeks to evaluate the clinical performance of a recently improved daily disposable contact lens to an established daily disposable contact lens that contains a wetting agent.
- Trial name
- NCT00600080
- Testing
- etafilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Depression
Study Where Pharmaco Magnetic Resonance Imaging (MRI) Effects of AZD6765 Will be Compared to Placebo in Depressive Male and Female Subjects
The purpose of this study is to determine the effect of a single dose infusion of AZD 6765 compared with placebo and ketamine on the blood oxygen level dependent signal using fMRI (functional Magnetic Resonance Imaging) in…
- Trial name
- NCT01046630
- Testing
- AZD6765, Ketamine
- Where
- 2 sites in United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Myopia
A Lifestyle Investigation With Spectacles and Daily Disposable Contact Lenses in Young Patients
The purpose of this study was to evaluate the relative benefits of daily disposable contact lenses versus spectacles in young adults.
- Trial name
- NCT01445652
- Testing
- nelfilcon A contact lens, Spectacles
- Where
- United Kingdom
- Volunteers
- 113 people
- Sponsor
- CIBA VISION