Clinical trials: Best Practice
Tobacco Use Disorder, Substance Use Disorder
Smoking Cessation CM for Veterans With or at Risk for Cancer
Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping…
- Trial name
- CM_TUD_Cancer (NCT06432985)
- Testing
- Focus Group, Contingency Management (CM), TUD Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Vision Impairment and Blindness, Glaucoma
Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice
In this cohort study, the investigators will test vision screenings in Danish general practice for patients over 70 years of age with minimum one chronic condition.
- Conditions
- Vision Impairment and Blindness, Glaucoma, Age-Related Macular Degeneration, Cataract
- Trial name
- DETECT (NCT07015034)
- Testing
- focus on vision impairment in older patients in general practice
- Where
- 2 sites in Denmark
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Parenting, Child Development
Evaluating a Strengths-based Community-grounded Intervention
Structural inequities and historical underinvestment in marginalized communities create developmental contexts that constrain access to high-quality education, healthcare, stable housing, and other critical resources.
- Conditions
- Parenting, Child Development, Brain Development, Household and Family
- Trial name
- NCT06701240
- Testing
- ParentChild+, FamilyNutrition+
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
PTSD, Depression
Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?
Evidence-based VA care is best for meeting Veterans' mental health needs, such as depression, PTSD and opioid use disorder, to prevent suicide or overdose. But some key evidence-based practices only reach 3-28% of patients.
- Conditions
- PTSD, Depression, Opioid Use Disorder
- Trial name
- NCT04208217
- Testing
- Modeling to Learn (MTL), Usual quality improvement (QI)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Birth, Satisfaction
Effectiveness of a Counseling Intervention in the Birth Plan for Pregnant Women (APLANT)
This study assesses the effectiveness of a birt plan (BP) counseling intervention in pregnant women. Half of the pregnant women receive the intervention and the other half receive the usual practice
- Trial name
- NCT03744416
- Testing
- Counseling based on Epstein's active decision making
- Where
- 4 sites in Spain
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Pain, Obesity, Childhood
Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition)
There is a gap between research and clinical practice, leading to variability in decision-making. Multifaceted implementation strategies are for improving implementation of best practices.
- Conditions
- Pain, Obesity, Childhood, Breast Feeding, Incontinence, Urinary
- Trial name
- SE24 (NCT06522529)
- Testing
- Multifaceted implementation strategy
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Penicillin Allergy
The Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal
Currently it is estimated that at least 25 million people in the United States are labeled as penicillin allergic although less than 1.5 million of these are truly allergic.
- Trial name
- NCT03702270
- Testing
- Penicillin Allergic Risk Stratification Best Practice Alert
- Where
- United States
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Prostate Cancer
PROSAIC-DS Study (PROState AI in Cancer - Decision Support)
Around 375,000 cancers are diagnosed in the UK annually, with this figure expected to reach 500,000 by 2035. As the number of different cancer treatment options and our scientific understanding continue to grow rapidly, it can be…
- Trial name
- PROSAIC-DS (NCT05355727)
- Testing
- Clinical decision support tool recommended outcome
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Financial Navigation Intervention in Improving Financial and Clinical Outcomes in Patients With Newly Diagnosed Gastric or Gastroesophageal Junction Adenocarcinoma
This trial studies how well a financial navigation intervention works in improving financial and clinical outcomes in patients with newly diagnosed gastric or gastroesophageal junction adenocarcinoma.
- Trial name
- NCT03986502
- Testing
- Media Intervention, Informational Intervention, Best Practice
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hearing Loss
Early Auditory Referral in Primary Care
Busy Primary Care providers (PCPs) have complex practices with many competing demands, making it difficult to improve their HL identification rates.
- Trial name
- EAR-PC (NCT03004937)
- Testing
- Family Medicine Hearing Loss Best Practice Alert
- Where
- 10 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Patient Engagement, Physician's Role
OPEN & ASK: Improving Patient-Centered Communication in Primary Care
This large scale multi-center cluster randomized controlled trial (RCT) is designed to assess the comparative effectiveness of three interventions in diverse ambulatory care settings and patient populations.
- Conditions
- Patient Engagement, Physician's Role, Physician-Patient Relations, Patient Activation
- Trial name
- NCT03385512
- Testing
- OPEN High Touch, OPEN High Tech, ASK Poster in Exam Rooms
- Where
- 3 sites in United States
- Volunteers
- 5,565 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego