Clinical trials: Best Practice
Pre-Eclampsia, Eclampsia
An mHealth Strategy to Reduce Pre-Eclampsia and Infant Death in Tanzania
The core of this study is a cluster randomized controlled trial (RCT) of antenatal clinics which are located in four districts in Tanzania.
- Conditions
- Pre-Eclampsia, Eclampsia, Hypertension, Pregnancy-Induced
- Trial name
- NCT03978429
- Testing
- Community-based Pre-eclampsia/Eclampsia Detection and Management, Strengthened Referral Network from Community to Referral hospital levels
- Where
- Tanzania
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Dr. Karen Yeates
Breast Carcinoma, Colorectal Carcinoma
Incorporating ePrognosis for the Encouragement of Smarter Screening for Breast and Colorectal Cancer in Older Adults
This clinical trial assesses the feasibility and acceptability of a smarter screening intervention for breast and colorectal cancer in older adults.
- Trial name
- NCT05021172
- Testing
- Best Practice, Informational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Smoking Behavior
MassCONECT (Massachusetts Community Networks to Eliminate Cancer Disparities Through Education) 4 Kids: Promoting Smoke-free Homes
This study evaluates the effectiveness of a motivational interviewing intervention with families with young children ages 0-5 where smoking is happening in the home to adopt a smoke-free home plan and reduce child's second-hand…
- Trial name
- NCT01537874
- Testing
- Motivational Interview, Usual best practices
- Where
- 3 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Heart Defects, Congenital
NIRS Guidance Trail in Children's Heart Surgery
Heart surgery in young children involves some risks. This study looks at a new type of monitor that may reduce these risks. Near Infrared Reflectance Spectroscopy (NIRS) aims to measure if enough blood reaches vital organs in the…
- Trial name
- NIRS (NCT02157597)
- Testing
- NIRS based management, Control
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cervical Carcinoma, Human Papillomavirus Infection
Multilevel HPV Self-Testing Intervention for the Increase of Cervical Cancer Screening Among Women in Appalachia
This trial studies how well a multilevel human papillomavirus (HPV) self-testing intervention works in increasing cervical cancer screening among women in Appalachia.
- Trial name
- NCT04411849
- Testing
- Best Practice, HPV Self-Collection, Informational Intervention
- Where
- 4 sites in United States
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Heart Failure
Handheld Ultrasound at Remote Locations
Heart failure causes a large patient and financial burden on the health care system. Pocket ultrasound imaging devices are utilized to improve time to correct diagnosis.
- Trial name
- NCT03547076
- Testing
- Focused ultrasound diagnostics
- Where
- Norway
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Helse Nord-Trøndelag HF
Atrial Fibrillation
Atrial Fibrillation (AF) and Electrocardiogram (EKG) Interpretation Project ECHO
The goal of this study is to determine the effectiveness of a direct-to-provider virtual education program ("AF and EKG Interpretation Project ECHO") for primary care providers who manage patients with atrial fibrillation (AF).
- Trial name
- NCT05890274
- Testing
- AF and EKG Interpretation Project ECHO
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Caregiver Burnout
Building Resilience In Caregivers of Trauma Survivors
The purpose of the study is to examine the role of demographics, pre-existing anxiety, depression, and substance use on caregiver depression anxiety, and substance use following a critical injury to a loved one, evaluate the…
- Trial name
- NCT04293016
- Testing
- Support as usual, Problem solving therapy, ICU diary
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Contraception, Immigrant
Implementing Best Practice Postpartum Contraceptive Services Through a Quality Improvement Initiative
Immigrant women in Europe has reported lower use of effective contraception, higher risks of multiple births, and unintended pregnancies compared to native-born women.
- Conditions
- Contraception, Immigrant, Post Partum
- Trial name
- IMPROVE-it (NCT05521646)
- Testing
- Quality Improvement Collaborative
- Where
- Sweden
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Head and Neck Carcinoma
Dyadic Yoga Intervention for the Improvement of Healthcare Utilization and Quality of Life in Patients With Head and Neck Cancer Undergoing Chemoradiation and Their Caregivers
This study evaluates if partner-based (dyadic) yoga programs may improve the quality of life of patients with head and neck cancer undergoing chemoradiation and their caregivers, and if it is a cost-effective option.
- Trial name
- NCT04890834
- Testing
- Best Practice, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Surgery--Complications
Cognitive Aids for the Management of Deteriorating Surgical Patients
Background and Goal of Study: Adherence to best practice management of emergencies improves through the use of cognitive aids. Aim of this study was to develop and validate cognitive aids for management of deteriorating surgical…
- Trial name
- CAMDS (NCT03812861)
- Testing
- CAMDS bundle
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Sedentary Behavior, Health Promotion
SWITCH Implementation Effectiveness Trial
The SWITCH (School Wellness Integration Targeting Child Health) project is a multi-component intervention designed to support school wellness programming and contribute to youth obesity prevention.
- Conditions
- Sedentary Behavior, Health Promotion, Overweight and Obesity, Healthy Lifestyle
- Trial name
- NCT04045288
- Testing
- Standard Implementation, Enhanced Implementation
- Where
- United States
- Volunteers
- 1,984 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Medication Adherence, Depressive Symptoms
Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)
The primary goal of this study is to test a minority stress model of psychological health outcomes for Black sexual minority men (BSMM) while using and not using a novel intervention named THRIVE 365.
- Conditions
- Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
- Trial name
- OTD (NCT05376397)
- Testing
- iTHRIVE 365
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Low Back Pain
Efficacy of Classification Based 'Cognitive Functional Therapy' in Patients With Non Specific Chronic Low Back Pain
A randomized controlled trial of the efficacy of classification based cognitive functional physiotherapy according to the system proposed by Peter O'Sullivan as compared to manual therapy and exercise in patients with non…
- Trial name
- NCT01129817
- Testing
- Cognitive Functional Therapy, Manual therapy and exercise
- Where
- Norway
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Tobacco Use Disorder, Substance Use Disorder
Smoking Cessation CM for Veterans With or at Risk for Cancer
Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping…
- Trial name
- CM_TUD_Cancer (NCT06432985)
- Testing
- Focus Group, Contingency Management (CM), TUD Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Micronutrient Deficiencies, Anemia
Effectiveness of Multiple Micro-nutrient Fortified Fudge on Nutritional Status of 3-5 Years of Age Children
Multiple micro-nutrient deficiencies in Pakistan is wide spread, there is dire need to address these by using smart solutions, among them multiple fortified product (fudge) is an alternate possible way to address this issue.
- Conditions
- Micronutrient Deficiencies, Anemia, Fortification, Undernutrition
- Trial name
- NCT03450174
- Testing
- Formative messgaes, Fortified product, Fortified product plus
- Where
- Pakistan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Diabetes Mellitus, Type 2
A Sleep Intervention (SLEEP-Extend) for Young Adults At-Risk for Type 2 Diabetes
The study is a prospective unblinded randomized trial to evaluate the feasibility of conducting a sleep extension intervention trial and the sleep extension intervention among the young adults.
- Trial name
- NCT03616171
- Testing
- SLEEP-Extend intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Emory University
Hip Osteoarthritis, Knee Osteoarthritis
Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial
This is a cluster randomized controlled trial to to evaluate the individual and health system impacts of implementing a new physiotherapist-led primary care model for hip and knee pain in Canada.
- Trial name
- NCT06358521
- Testing
- Physiotherapist-led primary care model for hip and knee pain, Usual physician-led primary care model for hip and knee pain
- Where
- Canada
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- Queen's University
Low-Birth-Weight Infant, Premature Infants
Analyzer of Human Milk: Applicability in Clinical Practice in Order to Achieve the Best Nutrition for Infants
An observational and prospective study involving about 30 healthy lactating mothers whose preterm infant(s) is/are hospitalized at Neonatal Intensive Care Unit after childbirth and who can provide enough maternal milk (3mL) to be…
- Trial name
- MISTU (NCT02971904)
- Testing
- human milk collection
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Early Life Nutrition Brazil
Depression and Anxiety Symptom, Anger
Implementing BEAM: A Scalable Digital Mental Health Program, for Families of Children Referred to Neurodevelopmental Services
Families of children with neurodevelopmental differences (NDDs) experience disproportionately high levels of parenting stress and mental health difficulties, including elevated depression, anxiety, and caregiver burden.
- Conditions
- Depression and Anxiety Symptom, Anger, Parenting, Stress (Psychology)
- Trial name
- NCT07837791
- Testing
- The Building Emotional Awareness and Mental Health (BEAM) Program
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manitoba