Clinical trials: Best Practice
Obesity, Adolescent
Young Adults With Early-onset Obesity Treated With Semaglutide
Introduction: The increasing prevalence of obesity is particularly pronounced among adolescents. Currently available treatment options consist of structured lifestyle interventions.
- Trial name
- RESETTLE (NCT05574439)
- Testing
- TCOC treatment, Semaglutide 3 mg/ml
- Where
- 2 sites in Denmark
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Signe Torekov
Only Child, Balance, Postural
The Validity and Reliability of the Four Square Step Test
This study will evaluate concurrent and discriminative validity, reliability and level of agreement between the Timed Up \& Go test and the four square step test in typically developed children.
- Trial name
- NCT03693482
- Testing
- the Four Square Step test
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Stress, Presenteeism
Kelaa Mental Resilience App for Employees
The goal of this randomized control trial is to detect and prevent work-related psychological stress among European workers early on, aiming to mitigate its adverse health consequences, including burnout and depression.
- Conditions
- Stress, Presenteeism, Absenteeism
- Trial name
- NCT05924542
- Testing
- Kelaa Mental Resilience App
- Where
- United Kingdom
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Spinal Anesthesia Skill, Ultrasound Imaging of Anatomical Structures
Evaluation of a Perceptual Learning Module on Spinal Ultrasound Among Residents.
This medical education research project aims to evaluate the impact of a directed perceptual learning module (PLM) on spinal sonoanatomy.
- Conditions
- Spinal Anesthesia Skill, Ultrasound Imaging of Anatomical Structures, Medical Education
- Trial name
- MAP-Rachis (NCT06533488)
- Testing
- Perceptual learning module, Control
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Corneal Edema Secondary to Corneal Endothelial Dystrophy
Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty
The purpose of this study is to report the early clinical outcomes in patients undergoing Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) for corneal edema secondary to corneal endothelial cell dysfunction, and to…
- Trial name
- DSAEK (NCT00744796)
- Testing
- DSAEK, Anterior Segment Optical Coherence Topography (OCT), Best Spectacle Corrected Visual Acuity (BSCVA)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dietary Habits, Childhood Obesity
Integrating Food Rx With Best Feeding Practices With EFNEP
To assess feasibility and acceptability of of integrating Food Rx and Best Feeding Practices with EFNEP participants via a pilot study.
- Conditions
- Dietary Habits, Childhood Obesity, Food Selection, Feeding Behavior
- Trial name
- NCT05881759
- Testing
- BEST study - Nutrition education only, BEST study - Nutrition education and feeding practices, BEST study - Nutrition education, feeding practices, and Food Rx
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Anterior Cruciate Ligament Injuries, Lower Extremity Problem
Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer
Anterior cruciate ligament (ACL) injuries of the knee are common in youth soccer players, and show an even higher prevalence in female soccer players.
- Trial name
- NCT05442879
- Testing
- Knowledge Translation Intervention, Educational handout
- Where
- United States
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Nicotine Vaping
Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping
The goal of this pilot study is to determine the feasibility of a randomized trial of the YES-CAN! (Youth Engaged Strategies to Change Adolescent Norms) program to prevent nicotine vaping among adolescents.
- Trial name
- YES-CAN! (NCT07009509)
- Testing
- YES-CAN! program
- Where
- United States
- Volunteers
- 1,166 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Birth, Satisfaction
Effectiveness of a Counseling Intervention in the Birth Plan for Pregnant Women (APLANT)
This study assesses the effectiveness of a birt plan (BP) counseling intervention in pregnant women. Half of the pregnant women receive the intervention and the other half receive the usual practice
- Trial name
- NCT03744416
- Testing
- Counseling based on Epstein's active decision making
- Where
- 4 sites in Spain
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Osteoarthritis, OA
Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis
The purpose of this study is to determine the effectiveness and safety of autologous alpha-2 macroglobulin rich plasma (A2MRP) injections in the treatment of knee osteoarthritis (OA).
- Conditions
- Osteoarthritis, OA, Knee Osteoarthritis
- Trial name
- A2MRP (NCT06329492)
- Testing
- Autologous Alpha-2 Macroglobulin Rich Plasma (A2MRP)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Opioid-Related Disorders, Benzodiazepine-Related Disorders
De-prescribing Program to Evaluate Falls in Older Adults
Purpose: The proposed study will implement and evaluate the effect of an opioid and benzodiazepine (BZD) de-prescribing intervention on falls risk in older adults.
- Conditions
- Opioid-Related Disorders, Benzodiazepine-Related Disorders, Falls Injury
- Trial name
- NCT04272671
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Behavioral Health Challenges
Brief Intervention at Adult Education
Many Americans fail to receive their high school diploma. Individuals enrolled in Adult Education classes have exited the K-12 education system without a high school diploma.
- Trial name
- NCT07102914
- Testing
- Screening, Brief Intervention and Referral for Treatment (SBIRT)
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Yale University
Acute Lymphoblastic Leukemia
MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence
This clinical trial identifies and addresses barriers to pediatric medication adherence among families of children with acute lymphoblastic leukemia.
- Trial name
- NCT06323044
- Testing
- Best Practice, Biospecimen Collection, Electronic Health Record Review
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Hypertension, Chronic Kidney Disease
Genetic Testing to Understand and Address Renal Disease Disparities
In this genomic medicine implementation pilot project, the investigators aim to conduct a randomized trial in a network of community health centers and primary care facilities to study processes, effects and challenges of…
- Conditions
- Hypertension, Chronic Kidney Disease, Genomics
- Trial name
- GUARDD (NCT02234063)
- Testing
- Immediate Genetic Testing
- Where
- 2 sites in United States
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Food Insecurity, Health Knowledge, Attitudes, Practice
Addressing Disparities in Food Access Among Young Children in Louisiana: A Farm to ECE Approach
The goal of this pilot project is to increase access to healthy food, improve diets, and reduce food insecurity and, in turn, reduce health disparities among low-income, minority children under the age of five attending early…
- Conditions
- Food Insecurity, Health Knowledge, Attitudes, Practice, Nutrition, Healthy
- Trial name
- FarmtoECE (NCT05745376)
- Testing
- Farm to ECE programming
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Healthcare Disparities, Reproductive Health
Evaluating the Mobile Clinic Model as a Means of Increasing Access to Reproductive and Sexual Health
The mobile health clinic evaluation study examines the impact of mobile health clinics on access reproductive and sexual healthcare services in underserved communities. Multiple mobile clinics operating throughout the U.S.
- Conditions
- Healthcare Disparities, Reproductive Health, Sexual Health, Program Evaluation
- Trial name
- MHCE (NCT05013710)
- Testing
- Complete Clinical Interaction
- Where
- 3 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Plan A Health, Inc
Hearing Loss
Clinical Investigation and Validation of a Self-fitted Air-conduction Hearing Aid
Approximately 48 million people in the United States have hearing loss or hearing difficulties in noisy environments. Concha Inc.
- Trial name
- NCT06167161
- Testing
- Hearing aid
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Concha Inc.
Healthy, Depression
Who Fares Best With Mindfulness Meditation
The overall aim of this observational study is to investigate how individual differences influence the effects of mindfulness meditation to uncover for whom mindfulness is beneficial and for whom it may be harmful.
- Conditions
- Healthy, Depression, Mental Health Issue
- Trial name
- NCT05862636
- Testing
- Mindfulness Training
- Where
- 3 sites in Belgium, United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. dr. Filip Raes
Anxiety Disorders, Depressive Disorder
Development of a Model for Shared Care in the Interface Between General Practice and Mental Health Care
Recent research has underlined that mental health of people with depression and anxiety has deteriorated over the last decades in Denmark as well as internationally, and has reached a degree where it is perceived as a global…
- Trial name
- NCT05172375
- Testing
- Shared Care Model
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Hepatitis C, Chronic Hepatitis C
Birth-Cohort Evaluation to Advance Screening and Testing for Hepatitis C
The Birth-Cohort Evaluation to Advance Screening and Testing for Hepatitis C (BEST-C) compares the effectiveness of the birth cohort HCV screening strategy with the current risk-based screening approach to detect previous…
- Trial name
- Best-C (NCT02123212)
- Testing
- Mailer, In-person recruitment, EHR Alert
- Where
- 3 sites in United States
- Volunteers
- 29,607 people, healthy volunteers welcome
- Sponsor
- National Opinion Research Center