Clinical trials: Blood sampling
Atopic Dermatitis, Psoriasis
Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
Chronic inflammatory skin diseases constitute a heterogeneous group of pathologies. They affect the skin but also other organs (joints, lungs, muscles, etc.). Their prognosis and response to treatments is extremely variable.
- Conditions
- Atopic Dermatitis, Psoriasis, Hidradenitis Suppurativa, Lichen Planus
- Trial name
- ImmuneSkinBank (NCT06599411)
- Testing
- Sampling
- Where
- France
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alzheimer Disease, Mild Cognitive Impairment
BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers
This research study aims to examine biomarkers of Alzheimer's disease as early as possible which could potentially be a screening tool for the general population.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia
- Trial name
- NCT05457998
- Testing
- Flutemetamol F18 Injection, [18F]-RO6958948 Injection, [18F]-MK-6240 Injection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Vitamin D, Vitamin B 12 and Folic Acid Concentrations, Micronutrient Status in Women of Reproductive Age
Vitamin B12, Folic Acid and Vitamin D Status in Women of Reproductive Age
This cross-sectional observational study aims to assess serum concentrations of vitamin B12, folic acid, and vitamin D in women of reproductive age in Herzegovina.
- Conditions
- Vitamin D, Vitamin B 12 and Folic Acid Concentrations, Micronutrient Status in Women of Reproductive Age, Vitamin Status Assessment
- Trial name
- NCT07100795
- Testing
- No Interventions
- Where
- Bosnia and Herzegovina
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Mostar
Metabolic Syndrome X
Mechanisms of Cerebrovascular Control
The objective of this study is to identify insulin-specific cerebral blood flow (CBF) control mechanisms, and establish cerebrovascular responsive baseline in younger (18-45 yrs) metabolic syndrome adults (MetSyn) who are at…
- Trial name
- NCT02936687
- Testing
- NOS Inhibition, ET-1 Inhibition, 3 Tesla MRI
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Gestational Diabetes Mellitus in Pregnancy, Hyperprolactinemia Pregnancy
Prolactin and FGF21 in Gestational Diabetes Mellitus
Prolactin (PRL) and PRL receptor (PRLR) signaling has been validated to play an important role in the modulation of glucolipid metabolism.
- Trial name
- NCT05528393
- Testing
- Blood sampling
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shen Qu
Complement Abnormality, Peripheral Blood Mononuclear Cells
The Role of Natural Killer, Complement and T-lymphocytes in COVID-19 Disease, a Prospective Monocentric Study
The current study is an open, non-randomized, monocentric, and interventional study. CoViD-19 patients will be recruited at UZ Brussel after informed consent is obtained.
- Conditions
- Complement Abnormality, Peripheral Blood Mononuclear Cells, Covid19
- Trial name
- TONIC (NCT05258643)
- Testing
- Blood analysis
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Periodontitis
Periodontitis and Inflammation: Study on Biological Samples
Periodontitis is a major public health problem because it is widespread in the adult population. It leads to the irreversible destruction of the anchoring tissues of the teeth, and represents a modifiable risk factor for systemic…
- Trial name
- CB-PARO2 (NCT06012019)
- Testing
- Biological sampling in Periodontitis Case, Biological sampling in Gingivitis Case, Biological sampling in Control Case
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Fertility
Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
The United States has the highest prevalence of obesity among all countries surveyed in 2012 by the Organization for Economic Cooperation and Development.
- Trial name
- NCT01894581
- Testing
- LOVAZA, GnRH
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypercholesterolemia
Screening for Hypercholesterolemia in Children Using Dried Blood Spot
Purpose: Heterozygous Familial Hypercholesterolemia (HeFH) is a common genetic disease responsible for premature atherosclerosis.
- Trial name
- CHOLESPOT (NCT05191355)
- Testing
- blood test
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
To Study Immunostatus of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT, To Study HIV Viral Load of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT
Observational Study of Effect of Radiation Therapy to Immuno Status in HIV-cancer Patients
Objectives: To study immunostatus (CD4) and HIV viral load in HIV-cancer patients before RT and last weeks of RT .
- Trial name
- NCT01546376
- Testing
- Radiation therapy, Venepuncture
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Obstructive Sleep Apnea
Aspirin Resistance in OSA Patients
Obstructive Sleep Apnea (OSA) patients are at increased risk of major cardiovascular events, so many patients take aspirin for prevention.
- Trial name
- NCT03930875
- Testing
- Aspirin Resistance testing
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Danbury Hospital
Pharmacokinetics
Antioxidant Bioavailability
A small cross-over trial on 3 different doses of liposomal vitamin C, comparing vitamin C uptake and downstream effects when 24 people consume 1, 2, and 5 grams on different test days, compared to placebo.
- Trial name
- NCT04463030
- Testing
- Liposomal vitamin C, 1 gram, Liposomal vitamin C, 2 grams, Liposomal vitamin C, 5 grams
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Collagen Analog, Platelet Activation
Platelet Activation by a Collagen Analogue in Hemorrhagic Situations
Dijon University Hospital and the Dijon-based NVH Medicinal Company have developed a recombinant mini-collagen NVH020B with platelet and Willebrand factor binding activity.
- Conditions
- Collagen Analog, Platelet Activation, Hemorrhage
- Trial name
- CAPTURE (NCT04483245)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obesity
Pleasure for Food and Endocannabinoids in Obesity
Disturbances in hedonic and motivational processes play a major role in the pathophysiology of obesity. To date, experimental approaches for the study of emotional and motivational processing rely on subjective assessment scales.
- Trial name
- PLOBEC (NCT01985139)
- Testing
- Computer-based tasks, Blood sampling
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Vaccine Breakthrough Infections
Evaluation of the Consequences of Poly Vaccination on Innate Immunity : Applications to a Military Population
In this study, the poly vaccination of military personnel prior to deployment will be analyzed in terms of central, peripheral and long-lasting changes in innate immunity.
- Trial name
- VaxInnate (NCT06110741)
- Testing
- Blood and saliva sampling, Survey
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Stroke, Rehabilitation
Extracellular Vesicles as Stroke Biomarkers
The combination of rehabilitation protocols and regenerative therapies offers the outstanding opportunity to promote and enhance the endogenous regenerative and repair processes occurring in tissues damaged or lost due to injury…
- Trial name
- EXO4STROKE (NCT05370105)
- Testing
- blood withdrawal
- Where
- 2 sites in Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Pertussis, Meningococcal Disease
Sources of COmplement in Meningococcal and Pertussis Serum Bactericidal Antibody Assays
This study is designed to allow cord blood sample collection from the cords of babies born in three gestational age windows: ≥37 gestational weeks, 32-36+6 gestational weeks and less than 32 gestational weeks to investigate…
- Conditions
- Pertussis, Meningococcal Disease, Prematurity
- Trial name
- COMPAre (NCT04023929)
- Testing
- Cord blood sampling
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Inflammation, Thrombosis
Investigation on the Effect of Smoking on the Expression of Pro- and Anti-thrombotic, Anti-oxidative, and Inflammatory Markers in Humans
Investigation on the effect of smoking on thrombus formation in humans. The expression of pro- and anti-thrombotic, anti-oxidative, and inflammatory markers will be assessed in 25-50 year old healthy smokers and non-smokers.
- Conditions
- Inflammation, Thrombosis, Smoking
- Trial name
- NCT02198937
- Testing
- Blood sample
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
CHLAMYDIA INFECTIONS
Immunopathogenesis of Chlamydia
Sexually transmitted Chlamydia trachomatis infections are a widespread public health concern due to their prevalence and potentially devastating reproductive consequences, including pelvic inflammatory disease, infertility, and…
- Trial name
- NCT00607659
- Testing
- No intervention, only observational
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Physiopathology
Early Pulmonary Effects of Excursion Deep Diving With Closed-circuit Gas Recycling: SPIDD Study
Scuba diving with closed circuit gas rebreathers is currently booming. Initially developed for professional and military diving, this type of diving has become very successful in recreational activities.
- Trial name
- SPIDD (NCT05775562)
- Testing
- Pre and post dive examinations
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
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