Clinical trials: Blood sampling
Severe Malaria, Uncomplicated Malaria
Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX
Understanding the sexual conversion of the malaria parasite is essential to interrupt malaria transmission. A new tool is developed that, based on expression analysis of sexual stage biomarkers, will estimate sexual conversion…
- Conditions
- Severe Malaria, Uncomplicated Malaria, Asyptomatic Plasmodium Infection
- Trial name
- IMMETASEX (NCT06064591)
- Where
- 3 sites in Belgium, Burkina Faso and 1 more
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Oximetry
Accuracy of ScanWatch Pulse Oximeter With Profound Hypoxia
Performance testing of pulse oximeters. The protocol involves brief stable arterial oxygen desaturation in healthy volunteers and sampling arterial blood when a stable level of hypoxia has been attained.
- Trial name
- NCT04380389
- Testing
- hypoxia
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Withings
Type 2 Diabetes, Obesity
Activation of Brown Adipose Tissue Thermogenesis in Humans Using Formoterol Fumarate (GB10)
One emerging, highly modifiable homeostatic mechanism for energy expenditure in humans is brown adipose tissue (BAT) thermogenesis.
- Trial name
- GB10 (NCT05553184)
- Testing
- Formoterol Fumarate 12 micrograms Inhalation Powder, Nicotinic Acid 50 MG Oral Tablet, Acute Cold Exposure
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Vitamin D Deficiency Disease
Vitamin D Supplementation in Warfighters
A genomics-based approach will target specific genes that may explain the response in biomarkers and symptoms before and after supplementation.
- Trial name
- NCT02954549
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
COVID, SARS-CoV 2
COVID-19: Herd Immunity Study in the Czech Republic
The aim of the SARS-CoV-2-CZ-Preval study is to quantify the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on…
- Trial name
- SARSCoV2CZPrev (NCT04401085)
- Testing
- SARS-CoV-2 diagnostic rapid test, Quantitative analysis of SARS-CoV-2 antibodies
- Where
- Czechia
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Fever, Viral Infection
Viromes in Infants Presenting With a Septic Syndrome
Fever in infants younger than 3 months is a common reason for emergency department visits and is associated with a significant risk of serious bacterial infections.
- Conditions
- Fever, Viral Infection, Bacterial Infections
- Trial name
- V-NOURSSE (NCT07470541)
- Testing
- biological samples
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Hemorrhagic Fever, Ebola
Open Study of the Duration of Immunity After Vaccination With GamEvac
The purpose of this study is to evaluate the post-vaccination immune status at different time points in subjects immunized against Ebola Virus Disease; to select an optimal regimen of product administration; and, to assess safety…
- Trial name
- NCT02911428
- Testing
- blood sampling collection
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Non-Alcoholic Fatty Liver Disease, Obesity
Direct Versus Indirect Effect of Amino Acids on Hepatokines
Liver hormones are key metabolic regulators and increased in metabolic diseases, including fatty liver disease. The underlying mechanisms driving the elevated levels are currently unknown and presents a major challenge in…
- Trial name
- Diaakine (NCT06240039)
- Testing
- Evaluating the acute effect of an amino acid infusion with and without a concomitant infusion of the somatostatin analogue octreotide to eliminate endogenous production of glucagon
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Yellow Fever (Healthy Volunteers), Biopsy/Methods
Baseline Assessment of Skin Resident Memory T Cells in Healthy Unvaccinated Participants
In The main GeKoSkimm trial (= A randomized controlled trial to compare the immunogenicity and skin imprinting of intradermal, subcutaneous and intramuscular yellow fever vaccination) the investigators try to understand whether…
- Trial name
- NCT07636551
- Testing
- Skin punch biopsy, Blood samples
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
HIV Seropositivity, Immunodeficiency
Evaluation of Post-SARS-CoV-2 Vaccinal Response in Immunocompromised Patients
The aim of this study is to identify both the humoral immunological response through the detection of induced antibodies and the cellular immunological response through the detection of interferon gamma production by functional…
- Conditions
- HIV Seropositivity, Immunodeficiency, Vaccination Reaction, Covid19
- Trial name
- NCT05672654
- Testing
- Blood draw
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Myeloproliferative Neoplasm
Role of the Circulating Procoagulants Microparticles in the Hypercoagulability of MNP Ph1-
Patients with myeloproliferative neoplasms Philadelphia chromosome negative (MPNsPh1-) such as Essential thrombocytosis (ET), Polycythemia vera (PV) and Primary Myelofibrosis (PMF) have a higher risk of arterial or deep-vein…
- Trial name
- MICROP-SMP (NCT02862366)
- Testing
- Blood sampling
- Where
- 3 sites in France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Pain
Jet Lidocaine for Pain Relief During Needle Insertion in a Pediatric Emergency Department
The purpose of this study is to explore to what degree, if any, Jet lidocaine will reduce or alleviate pain, as compared to Jet normal saline, in children undergoing needle insertion in the Pediatric Emergency Department (PED).
- Trial name
- NCT00681902
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Lung Cancer
DECAMP-1: Diagnosis and Surveillance of Indeterminate Pulmonary Nodules
The goal is to improve the efficiency of the diagnostic follow-up of patients with indeterminate pulmonary nodules by determining whether biomarkers for lung cancer diagnosis that are measured in minimally invasive biospecimens…
- Trial name
- DECAMP-1 (NCT01785342)
- Testing
- Biosample and Imaging Collection
- Where
- 15 sites in United States
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- Boston University
Pregnancy Related
Is the Plasma Concentration of CAPGDF15 Increased in Pregnancy? A Pilot Study
Background and Purpose During pregnancy, the hormone GDF15 rises between 100-200 times higher than before pregnancy. The significance of this dramatic increase is not clarified, but it has been shown that pregnant women with…
- Trial name
- CAP (NCT06268353)
- Testing
- blood sampling
- Where
- 2 sites in Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Kidney Diseases, Kidney Transplant
Sargramostim for Myeloid Dendritic Cell Deficiency
The study will determine whether administration of sargramostim will improve myeloid dendritic cell deficiency in various study groups, including healthy subjects and patients with chronic kidney disease, including those with…
- Trial name
- NCT03063242
- Testing
- Sargramostim, Blood samples
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Florida
Complex Regional Pain Syndrome Type I
Longitudinal Follow-up Study About Complex Regional Pain Syndrome (CRPS) Patients
Complex regional pain syndrome (CRPS) is a post-traumatic chronic pain condition characterized by pain and other symptoms typically affecting a distal limb.
- Trial name
- NCT04703647
- Testing
- Administration of questionnaires for prospective group, Blood samples for prospective group, Blood samples for control group
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Cystic Fibrosis, Endothelial Dysfunction
Vascular Health and Function in Cystic Fibrosis
The goal of this observational study is to learn whether blood vessel health and function differ between adults aged 40 years or older with cystic fibrosis (CF) who are taking CFTR modulator therapy and healthy adults of the same…
- Conditions
- Cystic Fibrosis, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- CF-VHF (NCT07904325)
- Testing
- Non-invasive vascular, cerebrovascular and autonomic assessment
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Heart Failure
A Study Evaluating Biomarkers in Participants With Heart Failure (MK-0000-344)
The aim of this 2-part study is to assess B-type natriuretic peptide (BNP) as well as other circulating and imaging biomarkers in myocardial function.
- Trial name
- NCT02364752
- Testing
- Blood Draw, Loop Diuretic Withdrawal/Salt Load
- Volunteers
- healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Glaucoma, Cataract
Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting
Microneedle (MN) is a mimic of a hypodermic needle, composed of hundreds of micron-sized, out-of-plane protrusions, typically arranged in arrays on a patch that can be applied onto the skin.
- Conditions
- Glaucoma, Cataract, Ophthalmological Disorder
- Trial name
- NCT05694858
- Testing
- Lignocaine-loaded maltose microneedle array patch, EMLA 5% patch
- Where
- Malaysia
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Cancer
Immune Reconstitution in Stem Cell Transplant Recipients
This specimen collection lab protocol will allow the investigators to prospectively study immune reconstitution in patients being treated for hematologic disorders and immune factors affecting graft versus host disease in…
- Trial name
- NCT02129543
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Miami
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.