Clinical trials: Blood sampling
Vitamin D Deficiency
The D-BIICEP Study
Athletes and active individuals have been identified as an at-risk group for a low vitamin D status, specifically those residing in countries of higher latitude (such as the United Kingdom).
- Trial name
- D-BIICEP (NCT03253055)
- Testing
- DEXA, pQCT, Lifestyle Questionnaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Puberty, Hyperandrogenism
Assessment of Day-night Secretion of Progesterone and LH Across Puberty
Hormones are substances that are made by the body and are sent directly out into the bloodstream to increase or decrease the function of certain organs, glands, or other hormones.
- Trial name
- LH (NCT02155933)
- Testing
- Blood sampling
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Aging, Exercise
The Effect of Exercise on Myokine Production in Aging Persons
The incidence of age-related diseases, such as cancer and cardiovascular diseases, rapidly rises. These days, age-related diseases cause the majority of all healthcare expenses.
- Trial name
- EXI-AGE (NCT05571709)
- Testing
- Exercise training, Questionnaire, Percutaneous muscle biopsy
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Pesticide Poisoning
Evaluation of Pesticide Exposure in the General Population
An association has been suggested with several diseases including cancer and IARC has classified several pesticides as carcinogenic, probably carcinogenic.
- Trial name
- SIGEXPOSOME (NCT02986763)
- Testing
- Questionnaire, blood, urine, hair and dust samplings
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Chronic Kidney Diseases, Liver Cirrhosis
The Role of the Kidneys and Liver in the Elimination of Glucagon
The study aims to evaluate the kinetics and effect of glucagon in patients with chronic kidney disease and liver cirrhosis and matched healthy subjects, respectively.
- Conditions
- Chronic Kidney Diseases, Liver Cirrhosis, Hyperglucagonemia
- Trial name
- MCR_EndCir (NCT05056584)
- Testing
- Glucagon infusion, Primed tracer infusion
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Sickle Cell Disease
Evaluating Thromboelastography (TEG) and ETP in Sickle Adults
The primary aim of this study is to investigate the reported enhanced coagulation status (prothrombotic status) in patients with sickle cell disease using 2 laboratory tests; thromboelastography (TEG) and Endogenous Thrombin…
- Trial name
- NCT02770534
- Testing
- blood test
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pulmonary Fibrosis, Sarcoidosis
Fibrosing ILD Biomarkers That Rule Acceleration
FIBRALUNG is a prospective cohort study with biobank of samples from patients with pulmonary fibrosis, aiming to explore the molecular determinants of different clinical outcomes, acute exacerbations and mortality.
- Trial name
- FIBRALUNG (NCT05635032)
- Testing
- Comprehensive clinical assessment and biological samples collection
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cardiovascular Risk Factors, Autoimmune Diseases
Universal Capillary Screening for Chronic Autoimmune, Metabolic and Cardiovascular Diseases: Feasibility and Acceptability Pilot Study.
This study represents a model for a public health program based on a general population screening for the most prevalent chronic metabolic, cardiovascular and autoimmune diseases across adulthood, childhood and adolescence.
- Trial name
- UNISCREEN (NCT05841719)
- Testing
- Screening test
- Where
- Italy
- Volunteers
- 1,535 people, healthy volunteers welcome
- Sponsor
- Emanuele Bosi
Distraction Methods, Pain Management
The Effects of Two Methods Applied on Pain and Fear During Phlebotomy in Children
Objective: This study aimed to evaluate the effects of using an externally vibrating dolphin-shaped Dolphin massage device and digital storytelling via tablet on pain and fear in children aged 3 to 6 years during blood…
- Conditions
- Distraction Methods, Pain Management, Fear, Narration
- Trial name
- No Acronym (NCT07816965)
- Testing
- External vibrating massage group, Digital Storytelling
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Sinem Basdemir
HIV Infection, Syphilis
Strengthening, Guidance, Health, Empowerment
The goal of this interventional study is to describe the care pathway following the use of an innovative home self-sampling method for the screening of six sexually transmitted infections (STIs) among sex workers met during…
- Conditions
- HIV Infection, Syphilis, Gonorrhea Infection, Chlamydia Infection
- Trial name
- ROSE (NCT07788599)
- Testing
- Self-sampling for six sexually transmitted infections
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
HPV Infection, HPV 16 Infection
Evaluation of the Q-Pad hrHPV Test System for Identifying Precancer
The EQUIP Study is testing whether high-risk human papillomavirus (hrHPV), the virus that causes most cervical cancers, can be accurately detected from menstrual blood collected at home.
- Conditions
- HPV Infection, HPV 16 Infection, High Risk HPV, Cervical Cancer Screening
- Trial name
- EQUIP (NCT07281599)
- Testing
- Q-Pad hrHPV Test System
- Where
- 3 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Qurasense
Pulmonary Hypertension Due to Lung Diseases
Collagen Fingerprinting for Stratification of Pulmonary Hypertension (PH) Patients
Chronic lung diseases such as pulmonary fibrosis and chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension.
- Trial name
- NCT07498244
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Haemophilia B, Haemophilia A
Thrombin Generation Numerical Models Validation in Haemophilic Case
Personalized therapy in haemophilia has not been reached yet. Treatment is substitutive and its doses are only based on the levels of deficient factor VIII (for haemophilia A) or IX (for haemophilia B).
- Trial name
- NCT02300519
- Testing
- blood sampling
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Atopic Dermatitis, Healthy
Pilot Tape Harvesting Study
The main objectives of the study are: To determine if RNA recovery from tape harvesting allows for the identification of a disease gene signature (e.g., interferon [IFN] signature for lupus) or other biomarkers that may…
- Conditions
- Atopic Dermatitis, Healthy, Discoid Lupus Erythematosus, Subacute Cutaneous Lupus Erythematosus
- Trial name
- NCT02125695
- Testing
- Skin Taping, Blood Sampling, Skin Biopsy
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Biogen
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Obstructive Pulmonary Disease
Apoptotic Cell (AC) Uptake by Human Alveolar Macrophages (AM)
The purpose of this study is to compare the ability of two types of white blood cells to eat dead host cells, and how this process affects their ability to protect the body from infection.
- Trial name
- NCT01099410
- Testing
- Fiberoptic bronchoscopy, blood draw, intravenous catheter
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Endometriosis
EUmetriosis: Insights Into the Pathogenesis of Endometriosis
This study investigates epigenetic changes in menstrual effluent and plasma from women with endometriosis to identify potential non-invasive diagnostic biomarkers for the disease.
- Trial name
- EUmetriosis (NCT07000786)
- Testing
- Endometrial biopsy or menstrual cup and blood sample
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
ST-elevation Myocardial Infarction (STEMI), Clonal Hematopoiesis of Indeterminate Potential (CHIP)
Clonal Hematopoiesis of Indeterminate Potential and Infarct Severity in ST-Elevation Myocardial Infarction
Clonal Hematopoiesis of Indeterminate Potential (CHIP) refers to the age-related expansion of hematopoietic stem cell clones carrying somatic mutations in leukemia-associated driver genes (e.g., DNMT3A, TET2, ASXL1) in the…
- Trial name
- CHIP in STEMI (NCT07615023)
- Testing
- Clonal hematopoiesis assessment and cardiac magnetic resonance imaging
- Where
- Austria
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
BK Polyomavirus, Kidney Transplant
Study of Anti-BKPyV Immune Responses in Kidney Transplant Patients With BKPyV Viremia
The human pathogen BK polyomavirus (BKPyV) is a ubiquitous, small, non-enveloped DNA virus that infects over 90% of people, typically in childhood with mild or no symptoms.
- Trial name
- NEPHRO-BK (NCT06988072)
- Testing
- blood sampling
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID 19, Respiratory Synctial Virus
COMMUNITY - the COVID-19 Immunity Study
The principal aim of the COMMUNITY study is to investigate immune responses following SARS-CoV-2 infection and/or vaccination in healthcare workers and hospitalized COVID-19 patients.
- Conditions
- COVID 19, Respiratory Synctial Virus, Influenza Virus, SARS-CoV-2 Virus
- Trial name
- COMMUNITY (NCT06784739)
- Testing
- Blood sampling, Mucosal sampling, PCR-test
- Where
- 2 sites in Sweden
- Volunteers
- 2,420 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
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