Clinical trials: Blood sampling
Primary Open Angle Glaucoma (POAG)
Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital
The goal of this observational study is to investigate the potential association between MMP-9 gene polymorphism and susceptibility to Primary Open Angle Glaucoma development in Egyptian patients The main question it aims to
- Trial name
- NCT07119905
- Testing
- genotyping assay by polymerase chain reaction
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Heart Diseases, Cardiac Diseases
Health eHeart BioBank
The purpose of the Health eHeart BioBank is to collect and store specimen (e.g. blood, DNA, tissue) for future studies at the University of California, San Francisco (UCSF) that will help determine changes and identify molecular…
- Conditions
- Heart Diseases, Cardiac Diseases, Vascular Diseases, Cardiovascular Diseases
- Trial name
- HeH BioBank (NCT06976502)
- Testing
- Blood Draw, Tissue Collection, DNA Collection
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Papillomavirus Infection
Normalizing Antibody Detection in First-void Urine
The aim of this study is to develop robust analytical protocols for the monitoring of vaccine induced immunity against the Human Papillomavirus (HPV) in first-void urine samples and to examine fluctuations of urinary HPV-specific…
- Trial name
- URINORM (NCT06582654)
- Testing
- Sampling
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Stress, Psychological
Contribution of L-Tyrosine to Recovery From Operational Strain on Return From External Operation
Operational conditions amplify soldier's constraints and stress factors, upsetting individual and collective adaptive landmarks.
- Trial name
- USOP (NCT04549194)
- Testing
- Blood collection, L-Tyrosine 500 Mg, Psychological questionnaires
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Blood Sampling Procedure, Healthy
Clinical Validation of the Fluispotter System for Serial Sampling of Venous Dried Blood Spots
This is a prospective, single-centre, non-comparative, non-randomized, open label, clinical investigation of the clinical performance and safety of Fluispotter.
- Trial name
- NCT04594577
- Testing
- Fluispotter
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fluisense ApS
Ehlers-Danlos Syndromes (EDS)
Evaluation of the Role of Serum Tenascin-X Levels in the Diagnosis of Hypermobile Ehlers-Danlos Syndrome
Thirteen types of EDS have been described based on their clinical manifestations and genetic backgrounds. Their diagnosis relies on personal and family medical history, together with established clinical criteria.
- Trial name
- DIAGNOSEDh (NCT07899554)
- Testing
- Blood sampling
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronavirus Infections
Study of the Incidence of SARS-CoV-2 Infection (COVID-19)
This is a prospective observational cohort study that will define the prevalence and incidence of CA-SARS-Cov2 infection using serological and PCR tests in a group of subjects during deconfinement.
- Trial name
- CovImmune 2 (NCT04429594)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiovascular Diseases, Carotid Intimal Media Thickness
Association of Mean Platelet Volume and Cardiovascular Disease in Children With End Stage Renal Disease.
Cardiovascular disease (CVD) is the major risk factor for death in end stage renal diseases (ESRD). Approximately 80% of ESRD patients have some degrees of left ventricular abnormalities at initiation of dialysis.
- Conditions
- Cardiovascular Diseases, Carotid Intimal Media Thickness, Left Ventricular Hypertrophy, Mean Platelet Volume
- Trial name
- NCT03759002
- Testing
- Imaging, Blood sampling
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Eating Disorders
Response to Acute Exercise in Eating Disorders
Individuals with eating disorders (ED) represent a high-priority clinical population, with among the highest mortality rates of any psychiatric disorder, and driven exercise (DEx) is a symptom evidenced in up to 80% of those with…
- Trial name
- NCT06213883
- Testing
- Biobehavioral Response to in-lab exposure to physical activity
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy, Nutrition, Healthy
Speed of Glucose Absorption
The purpose of this study is to look at how fast commercially available supplements containing carbohydrate can get into the bloodstream.
- Trial name
- NCT06375577
- Testing
- 45 grams Voom Pocket Rocket Electro Energy, 45 grams SIS Go Isotonic Energy Gel, 45 grams Maurten Gel 160
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Emergencies
Evaluation of Blood Sampling From a Pre-existed Peripheral Intravenous Catheter Line
Background: Peripheral Intravenous catheter (PIVC) is a frequently used device for intravascular access. It is usually indicated to administer intravenous fluid and medications.
- Trial name
- NCT05543772
- Testing
- Normal saline
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Bleeding
Efficacy of Tranexamic Acid and Epsilon-aminocaproic Acid in Reducing Bleeding and Transfusions in Cardiac Surgery
The investigators primary objective is to compare the effectiveness of epsilon-aminocaproic acid (EACA) and tranexamic acid (TA) in reducing bleeding and transfusion in cardiac surgery, with the hypothesis that TA is more…
- Trial name
- NCT02655653
- Testing
- Epsilon-aminocaproic acid administered, Tranexamic Acid administered
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pharmacokinetics
A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics
Kava is a dietary supplement on the US market and is experiencing a resurgence of its use. Its pharmacokinetic information, however, is lacking which is important for its future effective usage as a dietary supplement or…
- Trial name
- KavaPK (NCT03843502)
- Testing
- Kava Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Diabetes Mellitus, Type 2
Glucose Homeostasis and Incretin Effect T2DM in the Youth- a Study of the Malaysian Population
Early onset type 2 diabetes mellitus among adolescents/youth (YT2DM) is a rising phenomenon. The pathophysiology has been studied primarily on non-Asian populations while literature on incretin effect is scarce.
- Trial name
- NCT02845557
- Testing
- OGTT and IVGTT tests
- Where
- Malaysia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RCSI & UCD Malaysia Campus
Diabetes Mellitus, Type 2
Mechanisms of Endothelial Dysfunction in Type 2 Diabetes
Endothelial dysfunction of conduit arteries plays an important role in the development of cardiovascular complications associated with type 2 diabetes.
- Trial name
- DIAB-EETs (NCT02311075)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Venipuncture
The Effects of Aromatherapy on the Incidence and Severity of Acute Pain
The purpose of this research was to estimate feasibility of an aromatherapy pain management intervention to reduce pain and distress caused by venipunctures in a pediatric population.
- Trial name
- NCT03122574
- Testing
- Lavender Aromatherapy, Jojoba Aromatherapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Esophageal Cancer
The Utility of Circulating Tumour Cells and Plasma microRNA in Esophageal Adenocarcinoma
Circulating microRNA (circ miRNA) and circulating tumor cell (CTC) levels are hypothesized to be associated with response to chemoradiation in patients undergoing treatment for locally advanced esophageal adenocarcinoma.
- Trial name
- NCT02812680
- Testing
- Blood Draw
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Oral Premalignant Lesions as Leukoplakia and Lichen Planus, Oral Cancer
Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant Lesions
Aim: The current study targets linking serum and salivary dipeptidyl peptidase-4 with oral squamous cell carcinoma and comparing it with potentially malignant lesions and control to validate dipeptidyl peptidase-4 as a diagnostic…
- Trial name
- NCT06087042
- Testing
- serum and unstimulated salivary samples
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Rhinovirus
The Rhinovirus Hospitalization and Investigation of Nasal-airway Omics (RHINO) Study
The goal of this study is to determine the burden of Rhinoviruses (RVs) as a cause of acute, severe, respiratory illnesses leading to hospitalization.
- Trial name
- NCT07342582
- Testing
- Nasal Swab Healthy Surveillance, Nasal Swab Sick Samples, Nasal Swab Hospitalized Cohort
- Where
- United States
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Haemodialysis Complication, Major Adverse Cardiac Events
Novel Cardiovascular Biomarkers in Patients With Kidney Disease
Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should. End-stage kidney failure (ESKD) is the final, irreparable stage of chronic kidney disease (CKD), where kidney function…
- Trial name
- CBKD (NCT06037759)
- Testing
- Cardiac Biomarkers, Lipidomics, Proteomics
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
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