Clinical trials: Blood sampling
Horton Disease
Study of T Lymphocytes in Patients With Horton Disease
Giant-cell arteritis (GCA) is the most frequent vasculitis after 50 years. Corticosteroid therapy is the reference treatment for GCA.
- Trial name
- GAMAIT (NCT03313102)
- Testing
- blood samples
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pelvic Organ Prolapse
Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse
Data on smoking and POP are conflicting. In a study done by Alnaif et al, smoking was found to be associated with severe POP. The authors' proposed explanation was that smoking impairs tissue and wound healing.
- Trial name
- NCT01548105
- Testing
- Blood draw for the study participants
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Kidney Stone
Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones
Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.
- Trial name
- NCT07350369
- Testing
- Detect the levels of metabolites in blood and urine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cancer
Multi-Cancer Detection Observational Cohort Study
This study assesses the incorporation of Multi-Cancer Detection (MCD) testing, designed to detect many types of cancer, into clinical practice to understand both its use and effect in real world practice conditions.
- Trial name
- NCT06962995
- Testing
- Blood Sample, Surveys
- Where
- 3 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Blood Sampling Procedure, Healthy
Clinical Validation of the Fluispotter System for Serial Sampling of Venous Dried Blood Spots
This is a prospective, single-centre, non-comparative, non-randomized, open label, clinical investigation of the clinical performance and safety of Fluispotter.
- Trial name
- NCT04594577
- Testing
- Fluispotter
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fluisense ApS
Reproductive Issues
Physiologic Mechanisms Underlying Ovarian Follicular Waves During the Menstrual Cycle
The research aims to characterize changes in ovarian and pituitary hormones associated with the development of ovarian follicular waves during the human menstrual cycle.
- Trial name
- NCT05531357
- Testing
- Transvaginal ultrasound scans
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Familial Mediterranean Fever
Assessment of microRNAs Role in Familial Mediterranean Fever FMF Pathophysiology
Familial Mediterranean Fever (FMF) genetic diagnosis is well established for homozygous patients. On the other hand, although heterozygous individuals are theoretically healthy carriers, 1/3 of them will develop clinical symptoms…
- Trial name
- miRinFMF (NCT06033339)
- Testing
- Blood sampling
- Where
- 4 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Postoperative Care
The Comparison of Pulse Oximetry, End-tidal Capnometry, and Integrated Pulmonary Index (IPI)
To compare two ways to test breathing after surgery in acute care setting. One method tests oxygen level of the blood, and one method will test oxygen and the carbon dioxide that is breathed out.
- Trial name
- NCT01191528
- Testing
- capnostream 20, Oridian Medical 1987 ltd, Needham MA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allenmore Hospital
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Nutrition
Metabolic Signatures of Dairy Products Ingestion in Humans: Effect of Age
Despite the fact that dairy products are greatly consumed, it remains today very difficult to determine with a classical blood biochemical test whether a person has ingested a fresh fermented dairy product or just milk, while…
- Trial name
- FermentoMilk (NCT03500003)
- Testing
- Acute milk intake, Acute Yogurt intake
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sergio Polakof
Low Back Pain
Effects of Spinal Manipulative Treatment on Inflammatory Markers in Low Back Pain Patients
It is expected that mechanical low back pain (LBP) is associated with inflammatory changes localized to the affected tissues. Could such changes be detected in cells involved in the inflammatory process in an in vitro model? The…
- Trial name
- NCT01766141
- Testing
- Spinal manipulation
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Canadian Memorial Chiropractic College
Neurological Outcome, Cardiac Arrest
Out-of-hospital Cardiac Arrest (OHCA) Biomarkers
Few early prognostic indicators are currently available for patients' families and clinicians following out of hospital cardiac arrest (OHCA), and blood biomarkers may be of prognostic value in these cases.
- Conditions
- Neurological Outcome, Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Brain Anoxia Ischemia
- Trial name
- NCT03112486
- Testing
- blood draw
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Stress, Psychological
Contribution of L-Tyrosine to Human Decision Making in Stressful Situations
L-tyrosine is a chemical precursor of dopamine. Under specific conditions, tyrosine administration can increase brain dopamine levels and therefore several studies have explored whether tyrosine supplementation can have a…
- Trial name
- TYRO-STRESS (NCT04518254)
- Testing
- Blood collection, L-Tyrosine 500 Mg, Cognitive tasks
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy, Hyperalgesia
Influence of Genetics in Pain Sensitivity
The purpose of this study is to learn more about the role of genetics in pain sensitivity. Pain perception varies widely among individuals, and information gained from this trial may lead to better methods of preventing and…
- Conditions
- Healthy, Hyperalgesia, Pain
- Trial name
- NCT00001956
- Testing
- Blood draw, Oral surgery, Tissue biopsy
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Chronic Renal Failure
Evaluation of Two New Innovative Haemostasis Tests: Measurement of the Active Form of GTP-bound Rap1b (aRap1b) in Platelets and the Pro and Antithrombotic Balance of Circulating Endothelial Microvesicles (patEMV) (INNOV-CKD Test)
The aim of this PROJECT is to develop two biomarkers to assess the thrombotic and hemorrhagic risk of patients with chronic renal failure (CKD) treated with antiplatelet drugs following the occurrence of an acute coronary…
- Trial name
- INNOV-CKD test (NCT05765630)
- Testing
- BLOOD SAMPLES
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Death, HIV Infection
Community-based Evaluation of a Pilot PMTCT Project in Kafue District
In this study, the investigators will assess the population effectiveness of using routine HAART as a PMTCT strategy, through a community-based survey.
- Trial name
- NCT00753428
- Testing
- Community-based Survey
- Where
- Zambia
- Volunteers
- 4,129 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
Saliva and Plasma Endocannabinoids Concentrations According to Feeding Status and Body Mass Index
Up till now, the evaluation of the endocannabinoid system (ECS) in humans needs invasive procedures. The investigators managed in the lab to determine the levels of endocannabinoids in a small number of subjects.
- Trial name
- SALIVENDO (NCT01223157)
- Testing
- Biological data
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Respiratory Syncytial Viruses, Respiratory Tract Infection
Incidence of Severe Respiratory Syncytial Virus Infections in Preterm Brazilian Children
The primary objective of this study is to determine the incidence of severe RSV LRTI requiring hospitalization among infants born < 35 weeks gestational age for one year of follow-up.
- Trial name
- NCT00585481
- Testing
- Samples collection for viral diagnosis, Lung Function Analysis
- Where
- 2 sites in Brazil
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Abbott
Ageing
Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly
The investigators aim to investigate the association of midlife dietary and lifestyle factors on cardiac functional changes in the elderly.
- Trial name
- CardiacAging (NCT02791139)
- Testing
- Cardiovascular Magnetic Resonance Imaging (MRI), Echocardiography, Tonometry
- Where
- Singapore
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Adolescent Obesity
Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity
In the U.S., dietary fructose has increased in parallel with the increase in obesity and may promote the development of diabetes and other chronic diseases.
- Trial name
- NCT03567837
- Testing
- Fructose + Glucose Beverage
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Rogosin Institute
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