Clinical trials: Blood sampling
Multiple Sclerosis
Regulation of Lipid Metabolism in Autoimmune Disease: Multiple Sclerosis
The aim of this research is to understand how lipids such as cholesterol affect the disease process in people with MS.
- Trial name
- RELOAD-MS (NCT04053374)
- Testing
- Blood sampling
- Where
- 2 sites in United Kingdom
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University College, London
Neoplasms, Solid Tumor
Methylation Profile Test (Methylscape) in Body Fluids for Multi-Cancer Detection and Monitoring in Colombia
DNA methylation changes occur early and broadly during carcinogenesis. Methylscape is a rapid assay that detects global DNA methylation patterns in body fluids (blood, urine, and saliva) and may detect a cancer signal and predict…
- Conditions
- Neoplasms, Solid Tumor, Breast Neoplasms, Lung Neoplasms
- Trial name
- METHYLSCAPE-CO (NCT07741435)
- Testing
- Methylscape DNA methylation assay
- Where
- Colombia
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo
Amyotrophic Lateral Sclerosis
LONgitudinal and Integrated Evaluation of Biomarkers in reLation to phenotYpe in ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons, leading to paralysis and death.
- Trial name
- LONELYALS (NCT07312240)
- Testing
- Lumbar Puncture for analysis of Cerebrospinal Fluid, Deep Phenotyping, Routine blood chemistry analysis and genetic analysis
- Where
- Italy
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Liver Cancer, Biliary Tract Cancer
Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers
LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA.
- Conditions
- Liver Cancer, Biliary Tract Cancer, Pancreatic Cancer
- Trial name
- NCT06139042
- Testing
- Blood drawing
- Where
- China
- Volunteers
- 1,608 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Smoking
Research Study on the Effects of Smoking on Arteries
The current proposal, will elucidate the role of oxidant stress (OS) on arterial function as measured by flow mediated vasodilation.
- Trial name
- NCT00948454
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
RECURRENT PREGNANCY LOSS
Sperm DNA Fragmentation in Recurrent Pregnancy Loss
In human, 2% of couples experimented Recurrent pregnancy loss (RPL). Currently, while etiological investigations were performed, 40 to 50 % of RPL were unexplained.
- Trial name
- PARTHOM (NCT02572154)
- Testing
- Blood and sperm samples
- Where
- 3 sites in France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Biomarkers of Air Pollution Exposure
Biomarkers of Exposure to Air Pollutants (AEROTOX-2)
Nowadays, an increase of inflammatory chronic diseases and/or tumors incidence has been reported in part due to the rising in life expectancy.
- Trial name
- AEROTOX-2 (NCT02765529)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Heart Diseases, Cardiac Diseases
Health eHeart BioBank
The purpose of the Health eHeart BioBank is to collect and store specimen (e.g. blood, DNA, tissue) for future studies at the University of California, San Francisco (UCSF) that will help determine changes and identify molecular…
- Conditions
- Heart Diseases, Cardiac Diseases, Vascular Diseases, Cardiovascular Diseases
- Trial name
- HeH BioBank (NCT06976502)
- Testing
- Blood Draw, Tissue Collection, DNA Collection
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Recurrent Miscarriage, Infertility
Iron Status in Female Infertility and Recurrent Miscarriage
Multiple studies suggest a link between the iron status and the development of the endometrium. Therefore, a sufficient iron supply seems to relevant for female fertility and reproduction.
- Conditions
- Recurrent Miscarriage, Infertility, Iron-deficiency
- Trial name
- NCT05034250
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Determining the Blood-to-brain Link
In Canada, ~17 millions of adults between 30-64 y old could benefit from a prevention strategy to lower the risk of Alzheimer's disease (AD).
- Trial name
- NCT04279743
- Testing
- omega-3 phospholipids, omega-3 Triglycerides
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Obesity
Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors
The purpose of this study is to collect data to examine whether short-term consumption of non-caloric artificial sweeteners (NCASs), such as saccharin, can lead to changes in blood sugar levels and in the composition of the…
- Trial name
- ISTAR-micro (NCT03032640)
- Testing
- Oral Glucose Tolerance Test (OGTT), Assessment of dietary compliance, Stool sampling
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Elderly Volunteers
Characterization of Fecal Microbiota in a Population Aged 50 to 75 Years Targeted by Seasonal Vaccination
The goal of this interventional study is to constitute a biological samples collection collected from healthy elderly volunteers and used for scientific purposes.
- Trial name
- FIFTY+ (NCT05972590)
- Testing
- Biological samples collection (blood + feces)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bioaster
OBESITY
Molecules Associated with Pediatric Obesity
Childhood obesity is linked to obesity in adulthood and causes severe problems, particularly due to its relationship with metabolic syndrome, diabetes, cancer, and cardiovascular diseases.
- Trial name
- Thesis (NCT06775990)
- Testing
- Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
SARS-CoV-2, COVID-19
A Cohort of Patients With Possible or Confirmed SARS-CoV-2 (COVID-19)
SARV-CoV-2 infection was considered pandemic on March 11, 2020. The SARV-CoV-2 epidemic affected France from the beginning of March, spreading in particular from a 4-day large evangelical meeting of 2500 people on February 17 in…
- Trial name
- COVIDothèque (NCT04347850)
- Testing
- blood sample
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Epilepsy
Association of Brain Derived Neurotrophic Factor (BDNF) rs6265 Gene Polymorphism With Susceptibility to Epilepsy
Epilepsy is a common neurological condition that affects people of all ages.Recent studies found that epilepsy is associated with several chromosomal regions, where mutations in these regions cause neurological dysfunction.
- Trial name
- NCT05096871
- Testing
- Genotyping by Real Time PCR
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
D-Dimer as an Early Detector of Pulmonary Embolism
Correlation Between Computer Tomography Angiography and D-Dimer Level for the Diagnosis of Pulmonary Embolism
A blood sample was taken before starting the patients on any thrombolytic treatment. The positivity threshold for D-Dimer was above 250 ng/ml. CTPA was performed after performing blood sampling.
- Trial name
- NCT05862220
- Testing
- D-Dimer vs CTPA
- Where
- United Arab Emirates
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zulekha Hospitals
Barrett Esophagus
A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus
This study is being done to collect data on the potential use of a sponge on a string device as a non-invasive tool in evaluating patients with Barrett's Esophagus compared to healthy controls.
- Trial name
- NCT02560623
- Testing
- Biopsy, Biospecimen Collection, Endoscopic Procedure
- Where
- 6 sites in United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Critical Illness, Metabolism and Nutrition Disorder
Endogenous Energy Production in Critically Ill Patients
The aim of this study is to investigate when critically ill patients transition from a non-suppressible catabolism to a normal response to feeding.
- Trial name
- eEPIC (NCT07059988)
- Testing
- Stable isotope tracers, Parenteral nutrition
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Metabolism
Effect of Genetics on Metabolism of Efavirenz
This study will evaluate the effects of genetics on metabolism of the anti-HIV medicine efavirenz (Sustiva) and will see if Efavirenz interacts with bupropion (Zyban or Wellbutrin), a drug commonly used to treat depression and to…
- Trial name
- NCT00245986
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cancer, Breast Cancer
Assessment of Paclitaxel-Induced Neuropathy
The purpose of this study is to collect clinical data, blood samples, and self reported symptoms from patients that experience unusually severe neuropathy after treatment with paclitaxel.
- Conditions
- Cancer, Breast Cancer, Ovarian Cancer
- Trial name
- NCT01953159
- Testing
- Blood Collection, Patient Questionnaires
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Chicago
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.