Clinical trials: Blood sampling
Bipolar Disorder (BD), Bipolar Disorder (BPD)
Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models
This preclinical translational study aims to evaluate a new method of delivering lithium using gold nanoparticles for the treatment of bipolar disorder.
- Trial name
- GLAD (NCT07732933)
- Testing
- Peripheral blood sampling for PBMC isolation
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiovascular Diseases
A 3D Hydrogel Model to Assess Endothelial Cell-macrophage Interactions in Simulated Microgravity (OR-DRPD-SRI2019)
The proposal contained herein seeks to examine the effect of simulated microgravity on important cell-cell interactions that govern vascular health. The interest lies in endothelial cell (EC) and macrophage cell interactions.
- Trial name
- NCT04028752
- Testing
- Blood collected specifically for this study
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Insulin Resistance, Diabetes
Validation of a Novel Screening Test for Maternal Insulin Resistance
This will be a validation study of Quantose IR and Quantose IGT to predict insulin resistance and identify patients with prediabetes. This is a pilot study of 100 subjects.
- Trial name
- NCT03388697
- Testing
- Quantose IR and Quantose IGT analysis, HOMA IR the standard testing for insulin resistance
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Healthy
Clinical Trial Testing the BioSerenity Pulse Oximeter (EOXY) Efficacy, Performance and Safety in Healthy Volunteer
The purpose of the study is to test the performance and safety of the Bioserenity pulse oxymeter EOXY. For that, and in agreement with ISO60601-2-61 norm and FDA regulation, measures of heart rate, with a gold-standard, and SaO2…
- Trial name
- EOXY (NCT03614416)
- Testing
- EOXY device, Gold standard oximeter, SaO2 sampling
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- BioSerenity
Peripheral Arterial Disease
The Impact of Branched-Chain Amino Acid Metabolism on Limb Dysfunction in PAD
Test the theory that abnormalities in the large blood vessels that deliver blood to your leg and the very small blood vessels in your leg's muscles (invisible to the eye) work together to worsen your leg function and walking.
- Trial name
- NCT03490968
- Testing
- Supervised Exercise, Vascular Assessment
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Dental Caries, Pulp Necrosis
Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars
This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric…
- Conditions
- Dental Caries, Pulp Necrosis, Primary Tooth Pulpectomy, Pediatric Dentistry
- Trial name
- MORvNAOCL (NCT06971055)
- Testing
- Sodium hypochlorite, Moringa Oleifera Leaf Extract
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Virtual Reality, Pediatric ALL
Virtual Reality in the Management of Pain in Pediatrics: a Multi-center Randomized Clinical Trial (RealPED)
The goal of this clinical trial is to test if the use of virtual reality glasses reduces the pain and anxiety that children feel when they perform a blood test.
- Conditions
- Virtual Reality, Pediatric ALL, Pain, Procedural
- Trial name
- RealPED (NCT05902585)
- Testing
- Virtual reality
- Where
- 6 sites in Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Type 1 Diabetes
Integrating Insulin Delivery and Glucose Sensing in Subcutaneous Tissue for the Treatment of Type-1 Diabetic Patients
The study seeks to use microdialysis and microperfusion techniques to assess the feasibility of combining insulin delivery and glucose sensing at a single subcutaneous tissue site.
- Trial name
- NCT00812591
- Testing
- OGTT and CLAMP
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Cancer Survivor, Diabetes Mellitus
Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant
This pilot clinical trial studies computed tomography (CT) scans and biomarker analysis in diagnosing coronary artery disease (CAD) in patients who have undergone a stem cell transplant but have no symptoms of CAD.
- Conditions
- Cancer Survivor, Diabetes Mellitus, Hypertension
- Trial name
- NCT02077218
- Testing
- computed tomography, cytology specimen collection procedure, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Human Papillomavirus Virus
Observational Follow up of Prior HPV Vaccinees
HPV vaccines have been included in the national immunisation schedule since 2008, firstly as the Cervarix vaccine which protects against two HPV types and in 2012 as the Gardasil vaccine which offers protection against a further…
- Trial name
- HPVfollowup (NCT02811068)
- Testing
- venepuncture
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Public Health England
Diphtheria-Tetanus-Acellular Pertussis
Immunogenicity of a Single Dose of GSK Biologicals' Boostrix™ in Infants Prior to Primary Pertussis Vaccination, When Administered to Pregnant Women as Per Routine Practice in Bogota, Colombia
The purpose of the study is to support the recommendation of vaccination of all pregnant women in Colombia with Diptheria, tetanus and pertussis (dTpa) by studying the transfer of pertussis specific IgG antibodies from mother to…
- Trial name
- NCT03188458
- Testing
- Blood sample
- Where
- Colombia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Systemic Lupus Erythematosus, Systemic Sclerosis
Neutrophil Extracellular Traps in Systemic Sclerosis
Systemic sclerosis (SSC) is a systemic disease characterized by limited or diffuse cutaneous sclerosis, microangiopathy, overproduction of autoantibodies and variable organ damage due to vasculopathy and/or fibrosis.
- Trial name
- NET-SSC (NCT03374618)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Potassium Measurement
Evaluation of a Blood Potassium Measurement Device From Capillary Samples (ALPHA)
This is an open, prospective, and interventional study investigating the potassium measurement with the CardioRenal device in capillary blood. It will be conducted at one investigational site.
- Trial name
- ALPHA (NCT04907773)
- Testing
- Capillary blood sampling, Venous blood sampling, Arterio-venous blood sampling
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CardioRenal
Soil-Transmitted Helminths
Real World Evaluation of an Albendazole-Ivermectin Coformulation Safety and Effectiveness
An open-label, randomized by school, two-arm pragmatic trial, will be conducted involving two study sites in Sub-Saharan-Africa (SSA), Ghana and Kenya, to evaluate safety and effectiveness of the newly developed fixed dose…
- Trial name
- NCT06282315
- Testing
- Pre-screening Phase, Screenig Phase, Randomization
- Where
- 2 sites in Ghana, Kenya
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
COVID-19
Lymph Node Aspiration to Decipher the Immune Response of Beta-variant Recombinant Protein Booster Vaccine (VidPrevtyn Beta, Sanofi) Compared to a Bivalent mRNA Vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in Adults Previously Vaccinated With at Least 3 Doses of COVID-19 mRNA Vaccine.
In order to investigate whether a germinal center response occurs following vaccine boost and to characterize it based on the type of vaccine received, we aim to analyze Spike and/or RBD-specific germinal center B cells within…
- Trial name
- LymphoBOOST (NCT05951920)
- Testing
- Lymph node aspiration / Blood sampling
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1
Immune Profile in Subjects With New Onset Type 1 Diabetes
It is hypothesized that early changes in the immune system in New Onset Type 1 Diabetes Mellitus (NOT1D) subjects can be detected in immune cells from the inguinal lymph nodes (iLN), which will be distinct from changes observed…
- Trial name
- NCT02801942
- Testing
- Inguinal lymph node fine needle aspirate biopsy, Inguinal lymph node core biopsy, Peripheral blood collection
- Where
- 2 sites in United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Vitamin D Deficiency
Vitamin D During Pregnancy
Vitamin D insufficiency is common globally. Pregnant women, who need an increased supply of this vitamin for the proper development of the fetus, are a significant risk group.
- Trial name
- NCT01589783
- Testing
- completion of a questionnaire, Blood draw
- Where
- Israel
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Systemic Sclerosis
Klotho and Mineral Bone Density in Systemic Sclerosis
The present study recruits female patients aged 45-65 years with a diagnosis of Systemic Sclerosis according to the EULAR/ACR 2013 criteria and age and gender-matched healthy control subjects.
- Trial name
- NCT05777954
- Testing
- Possible Klotho effects on SSc clinical conditions, namely skeletal, fibrotic and microangiopathic damage, Evalution in healthy patients of bone mineral density, Klotho level and key bone-related cytokines
- Where
- Italy
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Skin Itching, Chronic Urticaria
Association of Thyroid Autoimmunity and Chronic Urticaria
Increase prevalence of thyroid autoimmunity is found in patients with chronic urticaria. About 5-34% of chronic urticaria patients is associated with the presence of thyroid autoimmunity who are euthyroid status whereas 5-10% of…
- Trial name
- NCT00737451
- Testing
- blood sampling
- Where
- Taiwan
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
HPV Genital Infection (Primary Condition Studied), Bacterial Vaginosis
Kinetics and Ecology of Human Papillomavirus Genital Infections in Young Women
Most genital infections by human papillomaviruses (HPV) are asymptomatic or benign and clear within a few months or years. There infections are much less studies than chronic infections, even though they represent the main…
- Conditions
- HPV Genital Infection (Primary Condition Studied), Bacterial Vaginosis, Chlamydiae Infection
- Trial name
- PAPCLEAR (NCT02946346)
- Testing
- vaginal sampling
- Where
- France
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
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