Clinical trials: Blood sampling
q Fever
Study on Seroprevalence and Risk Factors of Coxiella Burnetii (Q Fever) in the South of Reunion Island
Emergent and infectious diseases are a public health priority on Reunion Island. Amongst public health threats, the infection due to Coxiella burnetii (Q fever) seems to have appeared on Reunion island in 2007 with two…
- Trial name
- E-Q-RUN (NCT02898402)
- Testing
- blood sample and questionnaire
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Cerebral Infarction
TSK (Tryptophan - Serotonin - Kynurenine) Biomarkers Assessment in Stroke
Single-center, prospective, descriptive and biomedical research with controls, without health product. Depression is the second risk factor for stroke as tobacco smoking following hypertension.
- Trial name
- NCT02963545
- Testing
- Usual care patients in neurology department, blood and urines sampling, Psychiatric evaluation
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Versailles Hospital
Liver Cancer, Biliary Tract Cancer
Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers
LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA.
- Conditions
- Liver Cancer, Biliary Tract Cancer, Pancreatic Cancer
- Trial name
- NCT06139042
- Testing
- Blood drawing
- Where
- China
- Volunteers
- 1,608 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hereditary Hemorrhagic Telangiectasia
Prospective Descriptive Study of the Angiogenic T Cell Population in Subjects With Hereditary Hemorrhagic Telangiectasia (HHT)
Hereditary hemorrhagic telangiectasia (HHT) results from genetic deregulation of angiogenesis. It is characterized by mucocutaneous telangiectasia responsible for recurrent epistaxis affecting quality of life (anaemia, iron…
- Trial name
- TangRO (NCT03572556)
- Testing
- Blood samples, Epistaxis charts
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Breast Cancer, Pancreatic Cancer
B-GLUCANCER2 : A Pilot Study Evaluating a New Method for Cancer Detection by Measuring the Activity of Different Glycosidase Enzymes in the Plasma of Patients With a Localized Cancer.
The goal of this clinical trial is to develop a new cancer diagnostic and prognostic tool based on the dynamic and non-invasive detection of an exogenous volatile molecule, i.e., ethanol, from patients' samples.
- Conditions
- Breast Cancer, Pancreatic Cancer, Pulmonary Cancer, Volatile Organic Compound
- Trial name
- B-GLUCANCER2 (NCT07236177)
- Testing
- blood plasma sample, blood sampling
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Periodontitis
Periodontitis and Inflammation: Study on Biological Samples
Periodontitis is a major public health problem because it is widespread in the adult population. It leads to the irreversible destruction of the anchoring tissues of the teeth, and represents a modifiable risk factor for systemic…
- Trial name
- CB-PARO2 (NCT06012019)
- Testing
- Biological sampling in Periodontitis Case, Biological sampling in Gingivitis Case, Biological sampling in Control Case
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adrenal Insufficiency, Congenital Adrenal Hyperplasia
Dynamic Hormone Diagnostics in Endocrine Disease
The study will investigate 27 hour profiles of hormones in the subcutaneous tissue of healthy subjects and patients with Addison's, Congenital Adrenal Hyperplasia, Growth Hormone Deficiency, acromegaly, Cushings and Primary…
- Conditions
- Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Cushing Syndrome, Growth Hormone Deficiency
- Trial name
- ultradian (NCT02934399)
- Testing
- 27 hour subcutaneous fluid sampling
- Where
- 4 sites in Greece, Norway and 2 more
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Pharmacokinetics
Antioxidant Bioavailability
A small cross-over trial on 3 different doses of liposomal vitamin C, comparing vitamin C uptake and downstream effects when 24 people consume 1, 2, and 5 grams on different test days, compared to placebo.
- Trial name
- NCT04463030
- Testing
- Liposomal vitamin C, 1 gram, Liposomal vitamin C, 2 grams, Liposomal vitamin C, 5 grams
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Sleep Deprivation
Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction
Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks.
- Trial name
- STAK-Sleep (NCT05519644)
- Testing
- Sleep Deprivation, Heart Rate, Sleep Monitoring
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Vitamin k2 in Type 2 DM
Relation Between Plasma Vitamin K2 and Glycemic Control and Metabolic Parameters in Type 2 Diabetic Patients.
Background and Rationale: The agents inducing type 2 diabetes are yet to be clarified. Current studies show that several genetic and environmental parameters are associated with type 2 diabetes .
- Trial name
- NCT04387019
- Testing
- blood sampling
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arterial Puncture, Radial Artery Injury
Blood'up Device Versus Manual Palpation for Arterial Puncture in Healthy Volunteers: A Pilot Randomized Study Under Normal and Simulated Hypotension
Arterial puncture is a common procedure in the management of hospitalized patients. It is most often performed at the level of the radial artery and allows arterial blood gas analysis.
- Conditions
- Arterial Puncture, Radial Artery Injury, Hypotension, Healthy
- Trial name
- NCT07765199
- Testing
- Arterial blood gas, Simulated hypotension, Arterial Puncture using Blood'Up device
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Healthy Volunteers
Identification of New Tools for Predicting Natural Metabolic Performance of the Liver
The objective of this clinical trial is to identify endogenous compounds (substances naturally present in the human body) that may serve as predictors of the activity of a key liver enzyme, CYP2C19.
- Trial name
- Endo2C19 (NCT07014930)
- Testing
- Control session, Inhibition session, Induction session
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Caroline Samer
Hepatic Failure
Liver Function Assessment - Feasibility and Dosing Study
The purpose of this study is to 1) determine the feasibility of using Cardiox Liver Function Assessment System (LFA) to measure indocyanine green (ICG) clearance; 2) determine an adequate dose based on LFA technology and 3)…
- Trial name
- NCT02516319
- Testing
- ICG Dye
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cardiox Corporation
Menstrual Cycle, Oral Contraceptives
The Effect of Menstrual Cycle and Oral Contraceptive Pill Phase on Aspects of Exercise Physiology
This study will investigate the effect of menstrual cycle (MC) and oral contraceptive pill phase on aspects of exercise physiology and athletic performance in female athletes.
- Trial name
- NCT05683119
- Testing
- Exercise and blood draw
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
HIV,
Microparticles, Vector of Genetic Information During HIV Infection
The aim of the investigators study is to demonstrate in healthy subjects and a cohort of patients infected with HIV, the presence of miRNAs in circulating peripheral blood microparticles (MPs).
- Trial name
- NCT01687452
- Testing
- Blood samples
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Measurement of Blood Parameter Equivalency
Study to Investigate Blood Samples Drawn With the HemoIV System
The goal of this study is to compare blood drawn using a device called HemoIV to standard-of-care blood drawn from a vein in the arm or from an IV catheter. The HemoIV is a device that is attached to an IV line.
- Trial name
- NCT06415058
- Testing
- HemoIV
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cardiovascular Diseases, Chronic Disease
Nutrigenomics Diet Intervention Study Comparing Effects of Western and Balanced Diet in Healthy Subjects
Diet macronutrient relative composition, quality and quantity determines lifestyle disease, including cardiovascular disease, development.
- Trial name
- Foodgene (NCT00733018)
- Testing
- "Western" versus "balanced" macro nutrient diet composition
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Lack of Satiety
Fibersol-2 Clinical Trials Related to Appetite
Emerging research suggests fiber, particularly digestion-resistant maltodextrins such as Fibersol-2, may impact satiety, by decreasing hunger, prolonging satiation, and/or increasing satiety signals from the gut.
- Trial name
- NCT01305291
- Testing
- digestion-resistant maltodextrin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Severe Malaria, Uncomplicated Malaria
Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX
Understanding the sexual conversion of the malaria parasite is essential to interrupt malaria transmission. A new tool is developed that, based on expression analysis of sexual stage biomarkers, will estimate sexual conversion…
- Conditions
- Severe Malaria, Uncomplicated Malaria, Asyptomatic Plasmodium Infection
- Trial name
- IMMETASEX (NCT06064591)
- Where
- 3 sites in Belgium, Burkina Faso and 1 more
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Gastric Lesion, Gastric Precancerous Condition
Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer
The goal of this study is to characterize and validate a signature of circulating biomarkers in plasma, associated with the presence of gastric preneoplasia in patients with preexisting gastric lesion compared with a control…
- Conditions
- Gastric Lesion, Gastric Precancerous Condition, Gastric Cancer
- Trial name
- PREGASIGN#1 (NCT05854368)
- Testing
- Additional blood collection as part of a blood sampling performed during routine care or specific for the research if not part of routine care., Blood collection
- Where
- 8 sites in France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
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