Clinical trials: Blood sampling
Hereditary Spherocytosis
Hereditary Spherocytosis and Vascular Function
Background : Patients with hereditary spherocytosis (HS) are characterized by increased red blood cell (RBC) fragility and a loss of RBC deformability.
- Trial name
- VASCUSPHERO (NCT04451785)
- Testing
- blood sample, Pulse wave velocity
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Copd, Smoking
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco.
- Conditions
- Copd, Smoking, Tobacco Use
- Trial name
- Pre-COPD Pilot (NCT04722835)
- Testing
- Bronchoscopy with Bronchoalveolar Lavage (BAL)
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bone Turnover Rate Disorder, Calcium Metabolism Disorders
Effects of Lansoprazole on Bone Turnover Markers
Use of proton pump inhibitors (PPI) has increased in recent years. There are concerns that PPIs have possible negative effects on bone metabolism.
- Trial name
- NCT04814316
- Testing
- Blood and urine specimens
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Human Microbiome
Detection of Luminal and Mucosa-associated Microbiome in Healthy Controls vs. Local and Systemic Inflammation
This study should reveal differences in composition of luminal and mucosa-associated microbiome of the human gastrointestinal tract.Therefore bacterial species of different intestinal location sites (small intestine and colon)…
- Trial name
- NCT03157687
- Where
- Germany
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Anorexia Nervosa, Dysbiosis
Alteration of Symbiosis Intestinal Microbiota on Patients With Anorexia Nervosa
The purpose of this study will be to study the association between the level of psychic symptomatic of anorexia nervosa (AN) (intensity of food restriction, symptoms of anxiety and depression) and alteration of host environment…
- Conditions
- Anorexia Nervosa, Dysbiosis, Anxious Depression
- Trial name
- INT-METAVOSA (NCT05632497)
- Testing
- Stool and blood samples
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infection, Tuberculosis Infection
Micro RNA as Prediction and/or Prognostic Markers of IRIS in TB-HIV Co-infected Patients
The role of miRNAs in HIV disease is yet to be completely defined. Host miRNAs target certain HIV genes, thus can affect HIV replication and participate in viral control.
- Trial name
- miRNA (NCT03941210)
- Testing
- Detection of molecular Biomarkers
- Where
- Cambodia
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Malaria
Malaria Survey in the Tak Province Refugee Camps
According to the World Malaria Report, there were significant decreases in the number of P.falciparum (PF) malaria cases worldwide in the past decade.
- Trial name
- NCT01902797
- Testing
- Questionnaire
- Where
- Thailand
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Placenta Previa, Placenta Accreta Spectrum
Syncytiotrophoblast-derived Extracellular Vesicles in Placenta Previa and Accreta Spectrum
The main goal of this case-control study is to quantify the levels of circulating syncytiotrophoblast-derived extracellular vesicles (STBEVs) in maternal blood in a population of women with placenta previa and placenta accreta…
- Trial name
- PAS (NCT06867874)
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vitamin D
Vitamin D, Bones, Nutritional and Cardiovascular Status
Vitamin D is not seen anymore only as a phosphocalcic hormone, but also as having an effect on global health (anti-infective, anti-inflammatory, anti-tumour roles and cardiovascular protection).
- Trial name
- VITADOS (NCT01832623)
- Testing
- Exploration of Vitamin D roles
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Autistic Disorder
Proteomic Biomarker Tests in Blood Samples from Children with Autism Spectrum Disorder (ASD)
Behavioral testing is the gold standard for diagnosing autism spectrum disorder (ASD). These tests, including ADOS and ADI-R, are subjective, require trained staff to administer, are time-consuming, and can only be administered…
- Trial name
- NCT02168868
- Testing
- Blood draw, Stool Sample Collection, Urine Sample Collection
- Where
- Israel
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Benjamin Gesundheit
Diabetes Mellitus, Type 2, Insulin Resistance
Exercise to Restore 24h Rhythms in Metabolism
This study will investigate the effect of exercise training on 24h rhythms in substrate metabolism in overweight subjects with impaired glucose tolerance. Subjects will perform exercise training for 12 weeks.
- Trial name
- RESTORE (NCT04565418)
- Testing
- High-intensity interval training
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Carbohydrate Ingestion, Fuel Selection
Maple Products and Exercise Performance
The purpose of this study is to compare the acute metabolic responses and time-trial performance following the ingestion of carbohydrate solutions containing either maple syrup, maple sap, corn syrup, a commercial sport drink or…
- Conditions
- Carbohydrate Ingestion, Fuel Selection, Athletic Performance
- Trial name
- NCT02880124
- Testing
- Solution ingestion, Constant load cycling, Expired gas sampling
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Gestatiaonl Diabetes Mellitus, Insulin Resistance
Impact of Gestational Diabetes on Childhood Obesity
In this study, we aimed to investigate the relationship between obesity, glucose intolerance (insulin resistance), dyslipidemia and diabetes in children aged 5-12 born to mothers with Gestational Diabetes Mellitus (GDM) in…
- Conditions
- Gestatiaonl Diabetes Mellitus, Insulin Resistance, Dyslipaemia, Obesity &Amp; Overweight
- Trial name
- NCT07069296
- Testing
- blood samples were collected from participants, blood samples
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Diffuse Large B Cell Lymphoma
Characterization and Clinical Impact of the Gut Microbiota in Lymphoma
The study is a prospective observational single-center cohort study which compare the gut microbiome of newly diagnosed Diffuse Large B-cell Lymphoma patients with the gut microbiome of healthy controls.
- Trial name
- NCT06161896
- Testing
- Stool samples
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lars Møller Pedersen
Monkeypox Virus Infection
A One Health Study of Monkeypox Human Infection
This multidisciplinary project aim to understand the epidemiology of the monkeypox in Central African Republic through the identification of the animal reservoir, the clinical and epidemiological description of the human…
- Trial name
- AFRIPOX (NCT05058898)
- Testing
- blood samples, Scabs and pus samples
- Where
- Central African Republic
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Pulmonary Sarcoidosis
Breath Analysis in Patients With Suspected Sarcoidosis: The VOCs-IS Study
Sarcoidosis is a chronic condition which predominantly affects the lungs and lymph glands within the chest, however, may affect any organ within the body.
- Trial name
- NCT04318392
- Testing
- Breath Analysis, Pulmonary Function Tests, Blood sampling and storage for genetic analysis
- Where
- 2 sites in United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Healthy Adult Females
Pharmacokinetics of Tenofovir, Emtricitabine, Maraviroc, and Raltegravir in Cervical, Vaginal, and Rectal Tissues and Secretions
The purpose of this study is to develop a predictive antiretroviral pharmacokinetic model of mucosal fluid and tissue distribution in genital tract fluid, rectal fluid and 3 mucosal tissues.
- Trial name
- NCT01330199
- Testing
- Pharmacokinetic Sampling
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Arterial Puncture, Radial Artery Injury
Blood'up Device Versus Manual Palpation for Arterial Puncture in Healthy Volunteers: A Pilot Randomized Study Under Normal and Simulated Hypotension
Arterial puncture is a common procedure in the management of hospitalized patients. It is most often performed at the level of the radial artery and allows arterial blood gas analysis.
- Conditions
- Arterial Puncture, Radial Artery Injury, Hypotension, Healthy
- Trial name
- NCT07765199
- Testing
- Arterial blood gas, Simulated hypotension, Arterial Puncture using Blood'Up device
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
SARS-CoV 2, COVID-19
Evaluation of Rapid Diagnostic Solutions, Serological and Molecular Tests for COVID-19
Prospective study for clinical performance evaluation of COVID-19 diagnostic tests: detection of anti-SARS-CoV-2 antibodies by RDTs or ELISA (manual or automated), rapid diagnostic tests based on antigen detection, molecular or…
- Trial name
- ERap-COV (NCT04405492)
- Testing
- Taking blood samples (capillary and venous), saliva sampling and nasopharyngeal sampling., Capillary and salivary sampling
- Volunteers
- 1,210 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris