Clinical trials: Blood sampling
Fibromyalgia
FIbromyalgia anD GenetIcs Subgroups (FIDGIS)
Fibromyalgia syndrome (FS) is characterized by widespread pain and affect 0.5 to 5 % of the general population, with a higher prevalence in women.
- Trial name
- FIDGIS (NCT04624581)
- Testing
- Electrophysiological measurement of reflex nociceptive flexion threshold (RIII reflex) using Nicolet Vicking device
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pain
A Study to Assess Therapeutic Equivalence Between Test EMLA Patch With Marketed EMLA Patch in Healthy Subjects.
A double-blind, randomized, 2-period, placebo-controlled, single-center, crossover study, efficacy study demonstrating the therapeutic equivalence of the test cellulose disc (matrix) in EMLA patch and the current commercial…
- Trial name
- EMLA (NCT03313336)
- Testing
- EMLA test patch, EMLA current reference patch
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sickle Cell Disease
Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease
Background : Sickle cell patients have profound remodeling of their muscle microcirculation networks with signs of amyotrophy. However, the consequences of these muscle alterations on the functional status of muscles are unknown.
- Trial name
- DREPAMUSCLE (NCT03243812)
- Testing
- Blood sampling, Maximum Voluntary Contraction (MVC) test force, Localized muscle endurance test
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Fasting
Immunomodulatory Effects of Fasting in Healthy Adults
This is a clinical trial assessing the effects of fasting on the immune system in healthy adults. Immune profiling, gene expression profiling, and flow cytometry on peripheral blood mononuclear cells (PBMCs) will be performed and…
- Trial name
- NCT05104502
- Testing
- Dietary Fasting
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Volunteers
Effects of Parabolic Flight on Spatial Cognition and Hippocampal Plasticity
The main objective of this experiment is to assess the impact of parabolic flight on (1) spatial memory and orientation, (2) the changes in brain structure and function, and particularly the hippocampal formation, and (3)…
- Trial name
- HypoCampus (NCT02789007)
- Testing
- Assess the impact of parabolic flight
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Pertussis
Sero-prevalence of Anti-pertussis Antibodies and Disease Awareness Among Spanish Healthcare Professionals
This study aims to determine the sero-prevalence of anti-pertussis antibodies among healthcare professionals at hospital centres in Spain.
- Trial name
- NCT01706224
- Testing
- Blood sample, Data collection
- Where
- 3 sites in Spain
- Volunteers
- 757 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cirrhosis
Comparison of Covered and Bare Stent in TIPS
Investigators aim to compare the efficacy of 8 mm Fluency covered stent and bare stent in transjugular intrahepatic portosystemic shunt (TIPS) for the treatment of cirrhotic portal hypertension.
- Trial name
- NCT02540382
- Testing
- covered stent, bare stent
- Where
- China
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Influenza
Asymptomatic Flu Project
Although clinical presentation of influenza is often symptomatic, asymptomatic cases also occur. The knowledge of the incidence of asymptomatic influenza among healthcare workers is very important because of the risk of…
- Trial name
- AFP (NCT02868658)
- Testing
- Blood sampling, Nasal swab
- Where
- France
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Wakefulness Disorder, Narcolepsy
Hypersomnia in the Paediatric Population
This is a 36-month, multicentric, cross-sectional study involving a paediatric population aged 6 to 17 years. Three groups will be included: Group A: children from the general population with no complaints of sleepiness; Group B…
- Conditions
- Wakefulness Disorder, Narcolepsy, Idiopathic Hypersomnia
- Trial name
- SOMNO-PED (NCT07766343)
- Testing
- Sleepness and wakeness scale, Polysomnography, Actimetry
- Where
- France
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Microvascular Disease, Microvascular Complications
Comparison of Differencens in VO2-max, Perfusion of the Heart and Brain and Cognitive Performance Between Patients with Type 2 Diabetes and Healthy Age Matched Controls.
In the aging population, ischemic heart disease, stroke and dementia are increasingly prevalent. Diagnosis and treatment of the former two i.e., large-vessel coronary heart disease and endovascular thrombectomy of the brain in…
- Conditions
- Microvascular Disease, Microvascular Complications, Dementia, Diabetes Mellitus Type 2
- Trial name
- SVAT (NCT06628297)
- Testing
- PET
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Non Small Cell Lung Cancer
The Method ISET (Insulation by Size of Epithelial Tumor Cells)
The aim of this study is, i) to assess the presence and the frequency of CTC in NSCLC patients undergoing surgery by using cytopathological analysis after their isolation by size (ISET method), and, ii) to correlate the presence…
- Trial name
- NCT00818558
- Testing
- ISET Methode
- Where
- France
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Colorectal Cancer, Colorectal Adenoma
Volatile Markers in Digestive Cancer
The study is aimed to determine the potential of volatile marker testing for identification of gastrointestinal cancers (in particular - colorectal and gastric cancers), the related precancerous lesions in the stomach and colon.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Gastric Cancer, Peptic Ulcer Disease
- Trial name
- VOLGACORE (NCT02332213)
- Testing
- Breath sampling for volatile marker detection, Upper endoscopy with biopsies, Colonoscopy with biopsies or lesion removal when required
- Where
- 2 sites in Latvia, Lithuania
- Volunteers
- 2,022 people, healthy volunteers welcome
- Sponsor
- University of Latvia
D-Dimer as an Early Detector of Pulmonary Embolism
Correlation Between Computer Tomography Angiography and D-Dimer Level for the Diagnosis of Pulmonary Embolism
A blood sample was taken before starting the patients on any thrombolytic treatment. The positivity threshold for D-Dimer was above 250 ng/ml. CTPA was performed after performing blood sampling.
- Trial name
- NCT05862220
- Testing
- D-Dimer vs CTPA
- Where
- United Arab Emirates
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zulekha Hospitals
Suicide, Attempted, Mood Disorder
Functional Imaging of Psychic Pain
Suicidal behaviour (SB) represents a major public health problem, costing life in more that one million people every year worldwide.
- Trial name
- NCT01493323
- Testing
- Assessment of personality traits, Assessment of suicidal act, Assessment of depression
- Where
- France
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Post-Operative Confusion, Neuroinflammatory Response
Neuroinflammation and Alzheimer's Pathology in POCD
The purpose of this project is to investigate the role of both neural inflammation and pre-existing neurodegenerative pathology in the risk and pathogenesis of post-operative cognitive dysfunction (POCD).
- Conditions
- Post-Operative Confusion, Neuroinflammatory Response, Alzheimer Disease
- Trial name
- POCD (NCT05378659)
- Testing
- Montreal Cognitive Assessment, Stroop Test, 4AT Delirium
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Systemic Availability, Intestinal Absorption
The Systemic Concentration of Short-Chain Fatty Acids After Delivery in the Small and Large Intestine of Healthy Volunteers
The goal of this crossover study is to evaluate the systemic availability of short-chain fatty acids (SCFA) that are either administered in the small intestine or the colon in healthy volunteers.
- Conditions
- Systemic Availability, Intestinal Absorption, Metabolism, Short-chain Fatty Acids
- Trial name
- Sistine (NCT06082726)
- Testing
- SCFA
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy
Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Determining the Blood-to-brain Link
In Canada, ~17 millions of adults between 30-64 y old could benefit from a prevention strategy to lower the risk of Alzheimer's disease (AD).
- Trial name
- NCT04279743
- Testing
- omega-3 phospholipids, omega-3 Triglycerides
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Obesity
Pleasure for Food and Endocannabinoids in Obesity
Disturbances in hedonic and motivational processes play a major role in the pathophysiology of obesity. To date, experimental approaches for the study of emotional and motivational processing rely on subjective assessment scales.
- Trial name
- PLOBEC (NCT01985139)
- Testing
- Computer-based tasks, Blood sampling
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Traumatic Brain Injury, Post-traumatic Epilepsy
Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
The overarching goal of this study is to improve understanding of the long-range natural history of TBI and post-traumatic epilepsy (PTE) by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12…
- Trial name
- NCT05823766
- Testing
- In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Clinical Visit
- Where
- 9 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Colorectal Carcinoma
Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved Patients
This clinical trial evaluates the use of a blood test (Guardant Shield™) for colorectal cancer screening. Colorectal cancer is the third leading cancer and cause of death in the United States.
- Trial name
- NCT05716477
- Testing
- Biospecimen Collection, Survey Administration
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
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