Clinical trials: Clarithromycin
Helicobacter Pylori Infection, Dyspepsia
Assessment and Management of Chronic Dyspepsia in Eastern Uganda
Chronic dyspepsia, or a sensation of indigestion, remains an underdiagnosed and often inappropriately managed cause of morbidity in countries with limited medical resources.
- Trial name
- NCT04525664
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Omeprazole 40 MG
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy Volunteers
Evaluate Effects of Multiple Doses of Rifampin and Clarithromycin on the Single Dose Pharmacokinetics of Deflazacort
The primary objective of the study is to determine the potential effects of multiple doses of rifampin and clarithromycin on the single dose pharmacokinetics (PK) of the deflazacort active metabolite (21 desacetyl-DFZ) in healthy…
- Trial name
- NCT02286635
- Testing
- Deflazacort and rifampin, Deflazacort and Clarithromycin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- PTC Therapeutics
Non-steroidal Anti-inflammatory Drug Adverse Reaction
Research for Prevention and Treatment of NSAIDs Related Gastrointestinal Side Effects
We aim to evaluate the protective effects of eradication of HP and continue using Geranylgeranylacetone (GGA) on NSAIDs related gastroenterological lesions.
- Trial name
- NCT01547559
- Testing
- part1:teprenone, part1:EAC-T, part1:EA-EMC-T
- Where
- 2 sites in China
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
COVID-19 Respiratory Infection, FLU
Effect of Kunamin in SARS-CoV-2 RT-PCR Positive Covid-19 Patients
The primary objective of this study is to determine the safety and efficacy profile of the food supplement (KUNAMIN®) containing grape juice, seed, stem, and bark given to patients treated with the established treatment regimen…
- Conditions
- COVID-19 Respiratory Infection, FLU, Cold; Influenza, Bacterial Pneumonia
- Trial name
- NCT05417997
- Testing
- Kunamin®, Favipiravir, Enoxaparin
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- RAAS Nutritionals, LLC
Healthy
Bioequivaelnce Study of Clarithromycin 250 mg/5 mL Powder for Oral Suspension Under Fed Conditions
To compare the single-dose oral bioavailability of clarithromycin 250 mg/5 mL powder for oral suspension of Ranbaxy Laboratories with Biaxin 250 mg/5 mL granules for oral suspension in healthy, adult, human, male subjects under…
- Trial name
- NCT00775372
- Testing
- Clarithromycin 250mg/5mL
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Healthy
Evaluation of Metabolic Markers for the Prediction of DDI of Various CYP3A Substrates and Inhibitors
Evaluation and validation of metabolic markers for the prediction of drug-drug interaction of various CYP3A4 substrates (sildenafil) and inhibitors (erythromycin/itraconazole) in healthy male subjects
- Trial name
- NCT02975037
- Testing
- Sildenafil, Clarithromycin, Itraconazole
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy Adults
A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants
The purpose of this study is to determine the Effects of KP-001 on Metformin (a substrate of MATE1) and Midazolam (a substrate of CYP3A4) Pharmacokinetics and the Effect of Clarithromycin (potent CYP3A4/P-gp Inhibitor) on KP-001…
- Trial name
- NCT06227832
- Testing
- KP-001, Metformin, Midazolam
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kaken Pharmaceutical
Healthy
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of After Administrations of DWP14012 Alone and Combinations of DWP14012, Clarithromycin and Amoxicillin in Healthy Male Subjects
This is a randomized, open-label, multiple dose, two-part phase I clinical trial to compare the pharmacokinetics, pharmacodynamics and safety/tolerability of DWP14012 after administrations of DWP14012 alone and combinations of…
- Trial name
- NCT03487562
- Testing
- DWP14012 Amg, DWP14012 Bmg, Clarithromycin
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy
Effects of Single-dose and Steady-state TPV/r on the Steady-state Pharmacokinetics of Clarithromycin and a Preliminary Assessment of the Effects of a Standard High-fat Test Meal on the Steady-state Pharmacokinetics of Tipranavir
To determine the effects of single-dose and steady-state Tipranavir/Ritonavir (TPV/r) at 500 mg/200 mg bid on the steady-state pharmacokinetics of clarithromycin and to determine the effects of a standard high-fat test meal on…
- Trial name
- NCT02251769
- Testing
- Tipranavir, Ritonavir, Clarithromycin
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
H.Pylori Infection, H.Pylori Gastrointestinal Disease
Concomitant Versus Hybrid Regimen for H. Pylori Eradication
10 day concomitant versus 14 day hybrid regimen as first line H. pylori eradication treatment in a high clarithromycin resistance area. A multicenter, randomized, equivalence trial.
- Conditions
- H.Pylori Infection, H.Pylori Gastrointestinal Disease, H. Pylori Associated Phlegmonous Gastritis
- Trial name
- NCT03592069
- Testing
- 10 day concomitant regimen, 14 day hybrid regimen
- Where
- Greece
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
Helicobacter Pylori Infection, Chronic Gastritis
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
The aim of this study is to evaluate the efficacy and safety of a quadruple therapy consisting of berberine hydrochloride, minocycline, esomeprazole, and colloidal bismuth tartrate for the first phase eradication of Helicobacter…
- Trial name
- NCT06603688
- Testing
- esomeprazole, Bismuth, Amoxicillin
- Where
- China
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Healthy
Investigation Drug-drug Interaction Between Dabigatran and Clarithromycin
Dabigatran (Pradaxa ®) is a new oral anticoagulant. It is used to prevent venous thromboembolism in orthopedic surgery and has recently demonstrated efficacy and safety at least as good as anticoagulants in the prevention of…
- Trial name
- IMAGINE (NCT01385683)
- Testing
- Dabigatran then dabigatran and clarithromycin, Clarithromycin and dabigatran then dabigatran
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Helicobacter Pylori Infection
Helicobacter Pylori Eradication According to DPO-PCR Methods (K-CREATE) Study)
Clarithromycin-containing triple therapy is still the primary therapy approved by the Korean government. However, studies of antibiotic resistance have shown that regional resistance patterns to antibiotics such as clarithromycin…
- Trial name
- NCT04147065
- Testing
- Duration of eradication regimen
- Where
- South Korea
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Incheon St.Mary's Hospital
Helicobacter Pylori Infection
Triple Therapy Versus Quadruple Therapies in the First Line Therapy of Helicobacter Pylori Infection
Whether non-bismuth quadruple therapy (concomitant therapy) is more effective than bismuth quadruple therapy or triple therapy for 14 days remains unknown.
- Trial name
- NCT01906879
- Testing
- triple, quadruple, non-bismuth quadruple therapy
- Where
- 10 sites in Taiwan
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study was to evaluate the efficacy and safety of the triple therapy of berberine hydrochloride, vonorasan and amoxicillin for the primary eradication of Helicobacter pylori.It is hypothesized that berberine…
- Trial name
- NCT06514274
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Infection
The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection
As increasing the antibiotics resistance, the effectiveness of traditional Helicobacter pylori (H. pylori) therapies has been declined coincidentally. In this study, the investigators evaluated the efficacy of H.
- Trial name
- NCT02359331
- Testing
- H. pylori culture and antimicrobial susceptibility testing, 14 days empirical bismuth quadruple therapy (Proton pump inhibitor), Metronidazole
- Where
- South Korea
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Non-cystic Fibrosis Bronchiectasis、Chronic Sinusitis Without Nasal Polyps、Chronic Obstructive Pulmonary Disease
Study on Drug Interactions Affecting the Pharmacokinetics of RSS0343 Tablet
This study is a single-center, single-sequence, self-controlled, open design, aiming to investigate the effects of rifampicin and clarithromycin on the pharmacokinetics of RSS0343 in humans.
- Trial name
- NCT07696091
- Testing
- RSS0343 Tablet; Rifampicin Capsules, RSS0343 Tablet; Clarithromycin Tablets
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Reistone Biopharma Company Limited
Healthy
To Demonstrate the Relative Bioavailability of Clarithromycin 250 mg Tablets Under Non-Fasting Conditions
To demonstrate the relative bioavailability of Cilostazol 50 mg tablets under fasting conditions.
- Trial name
- NCT00881179
- Testing
- Clarithromycin 250 mg Tablets (Geneva Pharmaceuticals, USA), Biaxin (Clarithromycin) 250 mg Tablets (Abbott Laboratories, Inc, USA)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sandoz
Healthy
Comparative Bioavailability Study of Clarithromycin 500 mg Tablets in Fasting State
The objective of this study was to investigate the bioequivalence of Genpharm's clarithromycin tablets following a single, oral 500 mg (1 x 500 mg) dose compared to the Biaxin® filmtab® (Abbott Laboratories USA) administered…
- Trial name
- NCT00648960
- Testing
- Clarithromycin
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Gastric Cancer
The Efficacy of Serum Pepsinogen for Prediction of Metachronous Gastric Neoplasm
After endoscopic resection of early gastric cancer (EGC), there remained concerned about the development of the metachronous gastric neoplasm (MGN). The aim of this study was to evaluate the role of H.
- Trial name
- NCT02682446
- Testing
- H pylori eradication
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital