Clinical trials: Computed Tomography
Healthy Adult Participants, Synaptic Plasticity
Effects of Adolescent Synaptic Pruning
The study will use a PET-based measure of brain cell (neuron) connections (synapses) in young adults who have also obtained an MRI, to assess how the loss of brain cell connections (synaptic pruning) is captured by MRI-based…
- Trial name
- SPA PET (NCT07569718)
- Testing
- PET Imaging Scan using [11C]UCB-J
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beatriz Luna
Teaching Innovation, Medical Education
Effectiveness of Teacher-Student Interactive Immersive Mixed Reality Technology on Anatomy Education
Background: Novice surgeons often struggle to translate anatomical knowledge into clinical practice, primarily due to a lack of resources, significant variability in anatomical structures, and limited hands-on experience.
- Conditions
- Teaching Innovation, Medical Education, Anatomy Education
- Trial name
- NCT06739590
- Testing
- Learning with CT scans, Learning with 3D visualization models, Learning with 3D-MR visualization models
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Displaced Tooth
Assessment of Extraction of Primary Canines in Treating Mesioangular Displaced Permanent Canines
This research project is important because there is no gold standard to rely on regarding the effect of the extraction of primary canines as an interceptive treatment for children with mesioangular displaced canines.
- Trial name
- NCT03684525
- Testing
- Extraction of primary canines
- Where
- Saudi Arabia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Decayed Teeth
Morphological Root Canal Variation in C-shaped Canal Will be Assessed for Age by Using Cone Beam Computed Tomography
CBCT Data Of C-Shaped Canal In Mandibular Second Molar Will Be Assessed For Age.
- Trial name
- NCT04817852
- Testing
- CBCT data of c-shaped canal in mandibular second molar.
- Where
- India
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Chronic Obstructive Pulmonary Disease (COPD)
Temple Health Chest Initiative (THCI 2.0)
Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to significant costs on healthcare…
- Trial name
- NCT06933758
- Testing
- Determine COPD prevalence utilizing spirometry along with CT scans and symptom assessments in the THCI lung cancer screening populatio
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Temple University
Multiple Sclerosis
Entire-body PET Scans for Multiple Sclerosis
To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation, monitoring and measurement of both peripheral and central demyelination in multiple sclerosis (MS) patients.
- Trial name
- EPSMS (NCT04390009)
- Testing
- Entire-body PET-CT scans, Amyvid radiopharmaceutical
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brain Health Alliance
Neoplasms
68Ga-N188 PET/CT Imaging in Malignancy
The Nectin-4 protein belongs to the cell adhesion factors family and has a tissue-specific expression spectrum in normal human tissues.
- Trial name
- NCT05593107
- Testing
- [68Ga]N188
- Where
- China
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Coronary Artery Disease (CAD), Heart Disease
Using CTA Measures to Define Cardiac Risk In NFL Alumni
The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the presence of CAD in NFL alumni.
- Conditions
- Coronary Artery Disease (CAD), Heart Disease, Coronary Atherosclerosis
- Trial name
- GAMEFILM (NCT06831409)
- Testing
- Coronary computed tomography angiography
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- HeartFlow, Inc.
COPD, Small Airway Disease
The Prevalence of Small Airways Dysfunction In COPD Patients and The Impact on COPD Control
Chronic obstructive pulmonary disease (COPD) is a worldwide prevalent disease. During recent years, increasing attention has been directed to the importance of the contribution of small airways in respiratory diseases.
- Trial name
- NCT04384133
- Testing
- Impulse oscillometry, Spirometric pulmonary function test, Fractional exhaled nitric oxide (FENO) test
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Sibel Naycı
Lung Cancer
Clinical Validation of InferRead Lung CT.AI
Lung cancer is the second most common cause of cancer-related death in men and women. Early pulmonary nodule screening is an effective means to prevent lung cancer, which is no less important than the diagnosis and treatment of…
- Trial name
- NCT04119960
- Testing
- Aided read with InferRead Lung CT.AI
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Infervision
Young Adults, Lymphoma, Non-Hodgkin
Fitness Assessment in Young Adults Recovered From Lymphoma
Regular physical activity (PA) is associated with maintaining body composition, increased cardiorespiratory capacity, muscle mass and bone mineral density.
- Conditions
- Young Adults, Lymphoma, Non-Hodgkin, Hodgkin Disease
- Trial name
- CUPCAKE (NCT05188755)
- Testing
- Indirect calorimetric test during submaximal exercise
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Scapholunate Dissociation
Diagnosing Dynamic Scapholunate Instability with Computer Tomography
Scapholunate instability can result in debilitating pain, dysfunction, and secondary arthritis. If treatment is required, the instability should ideally be addressed in the dynamic stage, before non-reducible non-repairable…
- Trial name
- stressct (NCT06695260)
- Testing
- CT scan
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Regionaal Ziekenhuis Heilig Hart Tienen
Distal Radius Fracture, Scaphoid Fracture
Use of Digital Tomosynthesis for Detection and Case Management of Scaphoid and Distal Radius Fractures: A VolumeRAD Data Collection Study
The study described herein is being conducted to collect clinical data associated with diagnosis and treatment information using the VolumeRAD advanced application.
- Trial name
- NCT03856450
- Testing
- DTS, X-ray, MRI or CT
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Healthy Ankle
An Evaluation Of Healthy Ankle Motion And Morphology
Determine motion and morphology of the healthy ankle during simulated gait.
- Trial name
- NCT03619382
- Testing
- Cone Beam Computed Tomography, Radiographs
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Paragon 28
Eye Enucleation, Orbit Surgery
Post Enucleation Socket Syndrome Study
Superior sulcus deformity in post-enucleation socket syndrome (PESS) may pose a significant cosmetic blemish after enucleation surgery despite apparently adequate orbital volume replacement.
- Conditions
- Eye Enucleation, Orbit Surgery, Postoperative Complications
- Trial name
- NCT00347282
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Prostate Cancer
Carbon-11 Labeled Sarcosine in Prostate Cancer
Men with and without prostate cancer will have a PET/CT scan that measures the level of the amino acid sarcosine. PET is a scanning method that uses short lived radioactivity.
- Trial name
- NCT02462447
- Testing
- 11C-sarcosine, 11C-choline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Microarchitecture
Bone Microarchitecture in Women Practicing Golf
After the age of 50, one in three women and one in eight men will experience at least one fragility fracture during the rest of their lives.
- Trial name
- NCT02544399
- Testing
- 3D CT scan
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Obesity, Type 2 Diabetes Mellitus
Brown Adipose Tissue and Body Mass Index
In this study the investigators aim to investigate whether the sympathetic stimulation of BAT, as assessed with a 123I-metaiodobenzylguanidine single-photon emission computed tomography computed tomography scan, differs between…
- Trial name
- NCT02173834
- Testing
- 18F- fluorodeoxyglucose-positron emission tomography Computed Tomography scan and 123I-metaiodobenzylguanidine-single-photon emission computed tomography scan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Thoracolumbar Spine Fracture, Facet Joint Degeneration
Degenerative Changes After Treatment of Thoracolumbar Junction Fractures
This observational study will evaluate how degenerative changes in the facet joints and intervertebral discs develop over time after treatment of AOSpine type A2, A3, and A4 fractures of the thoracolumbar junction.
- Conditions
- Thoracolumbar Spine Fracture, Facet Joint Degeneration, Intervertebral Disc Degeneration
- Trial name
- NCT07672184
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sklifosovsky Institute of Emergency Care
Dental Situations
Can Dental Dedicated MRI Replace Low-dose CBCT Scanning in Dentistry
Magnetic Resonance Imaging (MRI) has is a useful diagnostic tool that offers advantages over conventional radiography techniques.
- Trial name
- DDMRI (NCT07008014)
- Testing
- Magnetic Resonance Imaging
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London