Clinical trials: Dietary Intervention
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
McArdle Disease
Oral Ketone Body Supplementation in Patients With McArdle Disease
McArdle disease, glycogen storage disease type V, is a rare metabolic disease. Affected individuals are unable to utilize sugar stored as glycogen in muscle.
- Trial name
- GSDV (NCT03945370)
- Testing
- β-hydroxybuturate esters
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Maintenance of Recommended Sodium Intake
Maintenance of Recommended Sodium Intake
The overall objective of this study is to assist the general public in achieving and maintaining the currently recommended sodium intake of 1500 mg/day through a reduced sodium intervention that emphasizes spices and herbs.
- Trial name
- SPICE (NCT01615159)
- Testing
- Behavior and lifestyle counseling
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cardiovascular Disease
Effect of Fruit and Vegetables on Insulin Resistance
Current evidence indicates that fruit and vegetable intake and dietary patterns rich in fruit and vegetables may be associated with reduced insulin resistance and may reduce the risk of the metabolic syndrome.
- Trial name
- FIRST (NCT00874341)
- Testing
- Fruit and vegetable intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Malnutrition, Infant, Malnutrition, Child
Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan
Early life nutrition is the key modifiable determinant of child growth, development, survival and diseases of adult onset. Pakistan ranks highest for neonatal mortality rate (44.2/1000 live births (LBs)) globally.
- Trial name
- NCT05590351
- Testing
- First diet: m-health coaching application, Face to Face counselling
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Obesity
Alpha and Omega of Lifestyle Therapy
The study aims to investigate the effects of double-blinded, randomized placebo-controlled n3-fatty acid supplementation (1000 mg day-1) and 13 weeks of resistance training on muscle function/biology and systemic health in…
- Trial name
- Alpha&Omega (NCT04279951)
- Testing
- Resistance exercise, Omega-3
- Where
- Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Childhood Obesity
An Ecological Approach to Addressing Childhood Obesity Issues in Imperial County
Our Choice is one of three CORD (Childhood Obesity Research Demonstration) studies funded by the Centers for Disease Control and Prevention in 2011 to test multi-sector, multi-level approaches to prevent and control childhood…
- Trial name
- Our Choice (NCT02197390)
- Testing
- Family wellness workshops, Obesity chronic care model, Physical activity, healthy eating, water drinking, healthy sleep promotion
- Where
- 2 sites in United States
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Spinal Muscular Atrophy
Prospective Evaluation of Infants With Spinal Muscular Atrophy:
SPOT SMA is a prospective NIH-supported clinical study targeting pre-symptomatic or recently diagnosed infants and children with Spinal Muscular Atrophy (SMA) types 1, 2, or 3 and their healthy control siblings less than 36…
- Trial name
- SPOTSMA (NCT02831296)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Adolescent
Nutrition Goes to School: a School-based Nutrition Intervention to Promote Healthy Eating Behaviour Among Adolescents
The goal of this cluster randomized controlled pilot trial is to assess the feasibility and effect of a school-based nutrition intervention program called "Nutrition Goes to School" (NGTS) in improving a healthy diet and physical…
- Trial name
- ESTEEM-NGTS (NCT06515288)
- Testing
- Nutrition Goes To School (NGTS) Program Intervention Package, Nutrition Education Capacity Building for Teachers and Management
- Where
- Indonesia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Portion Size
Using the Norm Range to Predict the Effect of Food Portion Size Reductions on Compensation Over 5 Days
Reducing food portion size is a potential strategy to reduce energy intake. However it is unclear at what point consumers compensate for reductions in portion size by increasing energy intake from other items.
- Trial name
- NCT03811210
- Testing
- portion size
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Breast Cancer Female
Impact of Pilates Method on Myofascial Stiffness, Cardiorespiratory Fitness and Quality of Life in Breast Cancer Women
The effectiveness of breast cancer treatment is quite well documented. Still, side effects can underpin other treatment-induced diseases such as osteopenia, diabetes, and especially cardiovascular dysfunction.
- Trial name
- NCT06419023
- Testing
- supervised physical activity intervention using the Pilates Method (exercises on the mat)
- Where
- Poland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Crohn Disease
Biologics and Partial Enteral Nutrition Study
Crohn's disease (CD) is a chronic, incurable condition associated with inflammation in the gut lining. It causes diarrhoea, severe abdominal pain, poor nutrition and adversely affects the quality of life of sufferers.
- Trial name
- BIOPIC (NCT04859088)
- Testing
- Partial Enteral Nutrition
- Where
- 4 sites in United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Insomnia
Self-help Lifestyle Medicine for Insomnia
This study will examine the effects of a self-help smartphone-based multi-component lifestyle medicine intervention (LM) for alleviating insomnia symptoms in a Chinese population.
- Trial name
- NCT04703283
- Testing
- Lifestyle Medicine
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy Volunteers
Effects of Bifidobacterium Longum BB536 on Incidence of Acute Diarrhea and/or Respiratory- Related Illnesses in Children
This project aims to study the benefits of probiotics namely Bifidobacterium longum BB536 in prevention of acute diarrhea and/or respiratory-related illnesses, which are found common among children in Malaysia aged from 2 to 6…
- Trial name
- NCT02434042
- Testing
- BB536
- Where
- Malaysia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Obesity
Trial of a Water Beverage Intervention for Promoting Modest Weight Reduction in Free Living Adults
The primary objectives of this clinical trial are to determine if replacing sugar sweetened beverages with water consumption promote weight loss over 6 months in overweight adults and if replacing sugar sweetened beverages with…
- Trial name
- NCT01017783
- Testing
- Dietary substitution A, Dietary Substitution B, Healthy Choices
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dietary Exposure
Discovery of Novel Biomarkers of Dietary Exposure in the EPIC Calibration Study
This proposal aims at identifying new biomarkers of dietary exposure using metabolomic approaches. This project is based on the European Prospective Investigation on Cancer and Nutrition (EPIC) Calibration Study and more…
- Trial name
- NCT03683654
- Testing
- Identify Biomarkers of Dietary Intake in Healthy Subjects
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Birth Weight, Small for Gestational Age at Delivery
Improving Birth Outcomes in Bangladesh
Maternal undernutrition is a global public health problem with far-reaching effects for both mothers and infants. Poor maternal nutrition negatively affects fetal growth and development.
- Conditions
- Birth Weight, Small for Gestational Age at Delivery, Diet; Deficiency, Gestational Weight Gain
- Trial name
- NCT05855551
- Testing
- Base cash transfer, Behavior change communication (BCC), Food basket
- Where
- Bangladesh
- Volunteers
- 4,620 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Metabolism and Nutrition Disorder
Metabolic and Functional Impact of Various Breakfast Models
In the present study the investigators compared the hormonal and metabolic effects of three meal loads very popular among Italian eating habits, both in the resting- and exercising state.
- Trial name
- NCT03240757
- Testing
- Breakfast, exercise
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
Prediabetes, Obesity & Overweight
Human Pilot Study for the Investigation of the Role of Bilberry and Olive Bioactives on Oxidative Stress Parameters and Inflammatory Markers.
Numerous plant-based foods contain bioactive compounds, in particular polyphenols, which have antioxidant, anti-inflammatory, and metabolic regulatory effects.
- Conditions
- Prediabetes, Obesity & Overweight, Inflamation, Oxidative Stress
- Trial name
- BIOTRANSFORM (NCT07659028)
- Testing
- supplementation, food
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Nutrition, Healthy
Improving Nutrition and Physical Activity in the Elderly Living at Home - ALAPAGE Study
CONTEXT Promoting healthy aging and preventing loss of autonomy are critical issues for many countries. In France, the 2018-2022 national health strategy emphasizes that adequate nutrition and regular physical activity are key…
- Trial name
- NCT05140330
- Testing
- ALAPAGE workshop, control workshop
- Where
- 2 sites in France
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Observatoire Regional de la Sante Provence-Alpes-Côte d'Azur
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