Clinical trials: Fentanyl
Anesthesia
Prediction of Hypotension During Induction of General Anesthesia
Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents.
- Trial name
- NCT06078228
- Testing
- Propofol - Fentanyl- Atracurium
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Anesthesia, Postoperative Complications
D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention
This study aims to compare two medications, dexmedetomidine and fentanyl, when used alongside a commonly used spinal anesthetic called bupivacaine in patients undergoing lower limb surgery.
- Conditions
- Spinal Anesthesia, Postoperative Complications, Dexmedetomidine, Fentanyl
- Trial name
- D-FAB-POUR (NCT07117565)
- Testing
- Intervention 1: Intrathecal Dexmedetomidine with Bupivacaine, Intervention 2: Intrathecal Fentanyl with Bupivacaine
- Where
- Nepal
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder
Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia
The climate crisis and environmental pollution are escalating day by day, making the reduction of carbon footprints increasingly important both on an individual and industrial level.
- Conditions
- Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder, Percutaneous Nephrolithotomy, Transurethral Resection of the Prostate
- Trial name
- NCT07363681
- Testing
- Dexmedetomidine + Remifentanil, Desflurane + Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pro-inflammatory Activity, Immunologic Activity Alteration
Pain, Opioids and Pro-Inflammatory Immune Responses
Providing pain management to the patient who abuses prescription opioids presents a clinical challenge, not only due to concerns about "drug-seeking", but because they have increased sensitivity to pain, a phenomenon identified…
- Trial name
- NCT01210066
- Testing
- Fentanyl, Cold pressor test, Fentanyl plus cold pressor test
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Analgesia
Depodur vs Fentanyl Infusion for Post-C/S Analgesia
Epidurally administered Depodur provides equal or superior analgesia as an epidural infusion of fentanyl for the first 48 hours after a cesarean section.
- Trial name
- NCT00762554
- Testing
- Depodur, Fentanyl
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goodman, Evan, M.D.
Sugammadex Reversal Time, Muscle Weakness
The Effect of Methylprednisolone on the Reversal Time of Rocuronium by Sugammadex in the Pediatric Patient Group
The aim of this study is to thoroughly investigate the interaction between methylprednisolone and sugammadex in the pediatric patient population.
- Trial name
- NCT06623370
- Testing
- methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Anesthesia
Propofol-fentanyl-ketamine (PFK) Combination Versus General Anesthesia Using Propofol and Fentanyl in Patients Undergoing Endoscopic Procedures.
Conscious sedation provides adequate control of pain and anxiety for the majority of routine endoscopic procedures as well as adequate amnesia.
- Trial name
- NCT04473846
- Testing
- PK general anesthesia, PFK combination
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Pain, Side Effect
Analgosedation for Elective Colonoscopy
Aim: The aim of the study was to to compare the analgesic effects of ketamine over fentanyl combined with propofol in analgesia-based elective colonoscopy with purpose of patient safety and satisfaction.
- Trial name
- NCT05421962
- Testing
- Ketamine
- Where
- Bosnia and Herzegovina
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital Zenica
Narcotism
Application of Propofol Mixed With Remifentanil in Fiber Colonoscopyand Analgesia in Fiber Colonoscopy
Fiber colonoscopy, as a terminal examination method for lower gastrointestinal diseases, often brings varying degrees of pain, discomfort, tension, and anxiety to patients.
- Trial name
- NCT06175156
- Testing
- Controlled analgesia/sedation, Intravenous combined anesthesia
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Handan First Hospital
Conscious Sedation Under Spinal Anesthesia
The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl
Since intrathecal fentanyl is known to sedation effect, intrathecal fentanyl will result in lowering propofol requirement for conscious sedation under spinal anesthesia.
- Trial name
- NCT01232270
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Craniotomy Surgery, Pediatric Patient Safety
The Effect Of Positive End-Expiratory Pressure on Optic Nerve Sheath Diameter In Pediatric Patients Undergoing Craniotomy in Supine Position
This study evaluated the effect of positive end-expiratory pressure (PEEP) on optic nerve sheath diameter (ONSD), an indicator of intracranial pressure, in pediatric patients undergoing craniotomy in the supine position.
- Conditions
- Craniotomy Surgery, Pediatric Patient Safety, Pediatric Patient, Positive End-expiratory Pressure (PEEP)
- Trial name
- NCT07370779
- Testing
- General Anesthesia, Anesthetic Agents, mechanical ventilation (MV)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pain
Determination of the Effective Volume of 0.125% Bupivacaine-fentanyl 5mcg/mL in Labour Epidurals
Different medications can be used as analgesics in labor epidurals. Bupivacaine is one of the most commonly used drugs for that purpose. The efficacy of a certain medication injected epidurally depends on the dose that is given.
- Trial name
- NCT01972269
- Testing
- Bupivacaine-fentanyl, Lidocaine
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Supracondylar Fractures
A Comparison of UGSB and GA to IV Narcotics and GA for Post-Op Pain in Children With Supracondylar Fractures.
This study compares nerve blocks to IV pain medicines in children with broken arms. We are trying to see if blocking the nerves in the broken arm results in better pain control and less side effects than injections of morphine…
- Trial name
- NCT02056288
- Testing
- Fentanyl, Ropivacaine
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hip Surgery, Post Operative Pain Control
Post Operative Pain Control After Pediatric Hip Surgery
Hip surgery in children is painful and the optimal modality for managing post-operative pain has not been established. This prospective randomized controlled trail compares lumbar plexus catheter (LPC), lumbar epidural catheter…
- Trial name
- NCT03435692
- Testing
- Lumbar Plexus Catheter, Lumbar Epidural Catheter, Patient Controlled Analgesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Labor Pain
Epidural Tap in Labor Analgesia FOR LABOR ANALGESIA
The dural epidural tap method is performed by creating a dural perforation with a spinal needle placed through epidural needle, followed by placement of a catheter into the epidural space.
- Trial name
- NCT05499234
- Testing
- Dolantin, Paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medipol University
Paravertebral Block
Effect of Addition of Fentanyl or Dexamethasone or Both to Bupivacaine in Paravertebral Block for Patients Undergoing Major Breast Surgery
This study evaluated the analgesic efficacy of fentanyl and dexamethasone in combination with bupivacaine for single-shot paravertebral block (PVB) in patients undergoing major breast surgery.
- Trial name
- NCT03480308
- Testing
- Fentanyl, Dexamethasone, Bupivacaine
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pregnancy, Cesarean Section
RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.
This is a prospective, randomized, double blind study of 75 patients (n=25 for each group) in which epinephrine (100mcg or 200mcg) or normal saline vehicle is added to intrathecal hyperbaric bupivacaine (0.75% bupivacaine…
- Trial name
- NCT03335293
- Testing
- 100 mcg Epinephrine, normal saline, 200 mcg Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Anesthesia Intubation Complication
Alfentanil and the Elimination of Sympathetic Responses to Tracheal Intubation During Rapid Sequence Induction of Anesthesia: A Probability-based Approach
Induction of anesthesia: After 3 minutes pre-oxygenation with 100% oxygen, a blinded dose alfentanil (0,10,20,30,40,50 or 60 µg/kg, followed by thiopental 4 mg/kg and rocuronium 0.6 mg/kg will be administered over 15 sec.
- Trial name
- NCT01518608
- Testing
- Alfentanil 0.5mg/ml (Rapifen , Janssen-Cilag)
- Where
- 2 sites in Norway
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Healthy
Study to Assess Adhesion Quality and Wear of Placebo JNJ-35685-AAA-G-023 Transdermal System in Healthy Adults
The purpose of this study is to assess 3 different scoring systems to evaluate the adhesive quality of placebo (an inactive substance that is compared with a drug to test whether the drug has a real effect in a clinical trial])…
- Trial name
- NCT02221726
- Testing
- JNJ-35684-AAA-023: Size 1; small patch, JNJ-35684-AAA-023: Size 2; large patch
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC