Clinical trials: Leucovorin, open to volunteers
Ampulla of Vater Carcinoma, Appendix Carcinoma
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
This study seeks to learn whether using the PAGODA algorithm to guide chemotherapy dosing will lower the chance of unplanned delays during chemotherapy for cancer in the gastrointestinal system compared to usual care.
- Conditions
- Ampulla of Vater Carcinoma, Appendix Carcinoma, Carcinoma of Unknown Primary With Gastrointestinal Profile, Colon Carcinoma
- Trial name
- NCT07283939
- Testing
- PAGODA algorithm, Oxaliplatin, Folinic Acid
- Where
- 368 sites in United States, Guam and 1 more
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Ampullary Adenocarcinoma
The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer.
Ampullary adenocarcinoma (AAC) is a rare gastrointestinal cancer with varying survival rates, particularly the aggressive pancreatobiliary (PB) subtype.
- Trial name
- ADAPTA (NCT06068023)
- Testing
- Folfirinox, Capox
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
One-carbon Metabolism in Healthy Individuals
Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA Formation
Periconceptional supplementation with folic acid - the synthetic form of the B-vitamin folate - reduces the occurrence of adverse pregnancy outcomes such as spina bifida.
- Trial name
- NCT01687127
- Testing
- Folic acid, 5-methyltetrahydrofolate, calcium salt
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia