Clinical trials: Prednisone
Acute Tubulo-Interstitial Nephritis
Prednisolone Treatment in Acute Interstitial Nephritis
A Prospective randomized trial with a primary objective to investigate the effect ofprdenisolone treatment in acute interstitial nephritis
- Trial name
- PRAISE (NCT04376216)
- Testing
- Prednisone
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Region MidtJylland Denmark
Uterus Transplant
Initiation of a Deceased Donor Uterine Transplantation Program at the University of Nebraska Medical Center
This study will explore the feasibility of initiating a uterine transplant program at UNMC. Using the procedural templates established by a successful Swedish team, the investigators will identify emotionally and socially stable…
- Trial name
- NCT02409147
- Testing
- Uterine Transplant
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Healthy Adults
Single and Multiple Ascending Dose Study of CORT113176 in Healthy Participants
This is a 3-part, first-in-human study of single ascending doses (SAD; Part 1) and multiple ascending doses (MAD; Part 2) of CORT113176 in healthy participants; Part 3 is an optional part to investigate whether CORT113176…
- Trial name
- NCT04249323
- Testing
- CORT113176 Lipid Capsule Formulation, Prednisone
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Pneumonia Hospital Acquired
The Applicability of Different Scoring Systems and Use of Steroids in the Treatment of Hospital Acquired Pneumonia
Cross sectional randomized clinical trial study will be done at Respiratory intensive care unit and Chest department at Assiut University Hospitals on All patients who developed hospital acquired pneumonia including ventilator…
- Trial name
- NCT03121690
- Testing
- Prednisone
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assiut University
End-Stage Renal Disease
Once Daily Dosing to Improve Medication Adherence and Patient Satisfaction in Kidney Transplant Recipients
Patient failure to take medications as prescribed (medication non-adherence) is now identified as an important cause of kidney transplant failure.
- Trial name
- OnceDaily (NCT02426502)
- Testing
- Conversion to Advagraf, conversion of non-immunosuppressant drugs to once daily, Conversion to once daily MPA
- Where
- 3 sites in Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy
A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)
Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic or PK study).
- Trial name
- NCT06633419
- Testing
- Opevesostat, Prednisone, Fludrocortisone acetate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Delayed Type Hypersensitivity
Characterization of the Molecular Mechanisms Involved in Delayed-Type Hypersensitivity Reactions to House Dust Mite, Diphencyprone, Nickel, and Tuberculin Purified Protein Derivative in Healthy Volunteers
This study will be conducted in 2 cohorts. In Cohort A, approximately 40 subjects will participate in a single-center, open-label, non-randomized, parallel-group trial to investigate the molecular mechanisms involved in…
- Trial name
- NCT03625219
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Systemic Lupus Erythematosus (SLE) or Cutaneous Lupus Erythematosus
A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
A Phase 1/2a Study of DB-2304 in Healthy Participants and Participants with Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus
- Trial name
- NCT06625671
- Testing
- DB-2304, Prednisone
- Where
- 7 sites in United States, Australia
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- DualityBio Inc.
Disorder Related to Renal Transplantation
Efficacy of Certican® in Combination With Myfortic® in Renal
The primary objective is to demonstrate the superiority of everolimus plus Myfortic® plus corticosteroids following CNI withdrawal at week 16 compared to tacrolimus plus Myfortic® plus corticosteroids as measured by the change in…
- Trial name
- HUSJ1 (NCT01399242)
- Testing
- Certican
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Universitário São José
Trigger Finger
Percutaneous Release vs Steroid Injection for Trigger Finger
Trigger fingers (TF) is the common cause of pain and disturbed function of hand. Many studies show that percutaneous release of A1 pulley has better outcome than the steroid injection.
- Trial name
- NCT05383040
- Testing
- Percutaneous release
- Where
- Nepal
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Hepatic Impairment, Healthy Participants
A Study to Evaluate Opevesostat (MK-5684) in Male Participants With Moderate Hepatic Impairment (MK-5684-009)
Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic [PK] study).
- Trial name
- NCT06860243
- Testing
- Opevesostat, Prednisone, Fludrocortisone acetate
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Kidney Failure, Chronic, End-Stage Kidney Disease
A Study to Evaluate the Effect of MK-5684 in Male Participants With Severe Renal Impairment (RI) and With End-stage Renal Disease (ESRD) (MK-5684-010)
The goal of the study is to learn what happens to levels of MK-5684 in people with severe renal impairment and end-stage renal disease versus a healthy person's body over time.
- Conditions
- Kidney Failure, Chronic, End-Stage Kidney Disease, Renal Failure, Chronic, Renal Failure, End-Stage
- Trial name
- NCT06814132
- Testing
- MK-5684, Prednisone, Fludrocortisone acetate
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Osteoporosis
Glucocorticoids Promote Osteoclast Survival
The purpose of this study is to determine the difference in response to bisphosphonate therapy in patients receiving excess glucocorticoids compared to patients with postmenopausal or male osteoporosis.
- Trial name
- NCT00572299
- Testing
- alendronate
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Arkansas