Clinical trials: Probiotic
Healthy
Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement
Randomized, Crossover, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with Daily Food Log, Stool Samples, Blood Draws, and Validated Questionnaires (GSRS, Bristol stool chart, and DQLQ) with Oral Dietary Supplement
- Trial name
- NCT06794619
- Testing
- Dietary Supplement with actives
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Vaginal Health
Effect of Oral Probiotic Yeast on the Composition of the Vaginal Microbiota in Healthy Women
This study is designed to evaluate the impact of oral consumption of the probiotic yeast CNCM I-3856 on healthy vaginal microbiota
- Trial name
- NCT03574844
- Testing
- Saccharomyces cerevisiae, dose 500, Saccharomyces cerevisiae, dose 1000
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
Prevention of Iron Deficiency
Efficacy of Probiotics on Iron Status During Pregnancy
Determine the effect of probiotics on improving iron status in a population of healthy, pregnant women.
- Trial name
- NCT02912416
- Testing
- Probiotics
- Where
- Sweden
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Probi AB
Depression, Sleep
Probiotic Administration on Mood
Researchers are looking to examine the impact of probiotic administration on symptoms commonly associated with depression, anxiety, stress, sleep quality, and associated emotional responses in healthy men and women.
- Conditions
- Depression, Sleep, Stress, Anxiety
- Trial name
- PAM (NCT05343533)
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Microbial Colonization
Colonization of Skin by M. Luteus Q24 Probiotic
The purpose of this study is to evaluate the skin quality improvement and colonization efficacy following the application of probiotic Micrococcus luteus Q24 (BLIS Q24) to the face from a serum format in healthy adults.
- Trial name
- NCT06137209
- Testing
- Active Comparator: Study Group A: Blis Q24 Serum at higher dose, Active Comparator: Study Group B: Blis Q24 Serum at lower dose
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- BLIS Technologies Limited
Obesity, Childhood
Pilot Study of Probiotics in Pre-diabetic Adolescents
This study evaluates the feasibility and effect of probiotics on glycemic control in obese adolescents.
- Trial name
- ProDP (NCT03109587)
- Testing
- Vivomixx
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Polycystic Ovary Syndrome
The Role of Dysbiosis of Gut Microbiota in the Pathogenesis of PCOS.
Polycystic ovary syndrome (PCOS) has a significant impact on women's health, but its pathogenesis is not yet clear. Dysbiosis of gut microbiota may play a role in the pathological change of PCOS.
- Trial name
- NCT03843736
- Testing
- Lifestyle intervention, Probiotic Agent, Oral contraceptive
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Dental Caries, Probiotics
Effect of Probiotics on Oral Homeostasis During Sugar Stress
The present study is a double-blinded randomized clinical trial with a duration of 28 days.
- Conditions
- Dental Caries, Probiotics, Gingivitis
- Trial name
- NCT05073393
- Testing
- Sugar stress
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
IBS - Irritable Bowel Syndrome, Diarrhea
A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients
The goal of this interventional clinical study is to study whether the consumption of QiMeiYan Probiotics in 25-35 young people with Mild irritable bowel syndrome (IBS Score 75 - 175) will reduce the frequency of Diarrhea.
- Trial name
- NCT05900752
- Testing
- QiMeiYan Probiotics
- Where
- 2 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shenzhen Precision Health Food Technology Co. Ltd.,
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Healthy Volunteers, Tolerability
Study Evaluating the Safety and Tolerability of a Probioitc
The rationale for the current study is to initially evaluate the safety and tolerability of a novel strain of the probiotic Limosilactobacillus reuteri (L. reuteri) in healthy volunteers.
- Conditions
- Healthy Volunteers, Tolerability, Safety
- Trial name
- NCT05044949
- Testing
- Probiotic
- Where
- 2 sites in Sweden
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Low Iron Stores
The Effect of Lactobacillus Cultures on Iron Bioavailability.
The purpose of this study is to determine the effect of a lactic acid fermented oat gruel on iron absorption in the upper and lower part of the intestine, respectively.
- Trial name
- NCT00283491
- Testing
- Active Lactobacillus plantarum 299v, Inactive Lactobacillus plantarum 299v
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Abdominal Obesity
Single Strain Probiotic
Probiotics have been recognized as functional foods with beneficial effects against obesity and cardiometabolic diseases, such as dyslipidemia, type 2 diabetes and the reduction of visceral fat mass, body weight and waist…
- Trial name
- CHOICE (NCT05882149)
- Testing
- Single strain probiotic
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Rosa Sola
Eczema, Atopic Dermatitis
Management of Eczema by Specific Probiotic Strains
To investigate the therapeutic effect of a selected probiotic mixture on the severity of AD in infants aged 0-15 months. The probiotic mixture has been studied in laboratory setting and has proven IL-10 stimulating effects.
- Trial name
- BAMBOO (NCT01230190)
- Testing
- Ecologic ® Panda II
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Agentschap NL
Prediabetic State, Dysglycemia
Clinical Trial to Evaluate the Efficacy and Safety of the Probiotic Strains Limosilactocillus Reuteri DSM 32910 and Lacticaseibacillus Paracasei DSM 32851 on Glucose Homeostatis in Prediabetic Adults
The aim of this international, randomized, parallel arms, double-blind, placebo-controlled clinical trial is to investigate the safety and efficacy of a combination of the two Lactobacillus strains (NZ-GHMH-01) on glucose and…
- Trial name
- NOVOGLUCOSE (NCT04767789)
- Testing
- NZ-GHMH-01
- Where
- 8 sites in France, Romania and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Healthy
Probiotic Formula and Infant Growth
This is a growth study of full-term, formula-fed infants randomized to receive a partially hydrolyzed whey protein formula with and without probiotics for the first four months of life.
- Trial name
- NCT01476397
- Testing
- Control infant formula, Test infant formula
- Where
- 8 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Weight Management
Effect of a Probiotic, Lactobacillus Gasseri BNR17, on Body Composition and Weight Management in Overweight Adults
Lactobacillus gasseri BNR17™ has shown promise in several pre-clinical and randomized controlled clinical trials for weight management outcomes.
- Trial name
- NCT04260997
- Testing
- Lactobacillus gasseri BNR17™ capsule
- Where
- Ireland
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- UAS Labs LLC
SARS-CoV Infection, Corona Virus Infection
Microbiome Therapy in Covid-19 Primary Care Support
This double-blind, randomized, placebo-controlled study aims to investigate whether a throat spray containing probiotic bacteria (i.e.
- Trial name
- MiCel (NCT04793997)
- Testing
- Microbiome spray
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Lifestyle, Diet
Methylation Diet and Lifestyle Study
The maintenance of health and the progression of disease are associated with an individual's genetic make-up and environmental factors, including lifestyle choices (such as diet, exercise, behaviors, stressors, sleep, tobacco and…
- Conditions
- Lifestyle, Diet, Healthy
- Trial name
- MDL (NCT03472820)
- Testing
- Diet Recommendations, Lifestyle Recommendations, Exercise Recommendations
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National University of Natural Medicine
Stress, Cognition
Probiotic Intervention for Stress and Cognition
The effect of probiotics on stress and cognitive function in healthy adults with moderate stress
- Trial name
- NCT04931082
- Testing
- Probiotics
- Where
- Ireland
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Probi AB
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