Clinical trials: Probiotic
Recurrent Aphthous Ulcers
The Salivary and Faecal Microbiome of Recurrent Aphthous Stomatitis Patients Before and After Treatment With Probiotics
Recurrent aphthous stomatitis (RAS) is one of the most common ulcerative diseases affecting the oral mucosa. The aetiology remains unknown, but several local, systemic, immunologic, genetic, allergic, nutritional, and microbial…
- Trial name
- NCT02976922
- Testing
- Probiotic lozenge
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
The Role of Synbiotics in Modulating Host Physiology Via the Gut Microbiome
The current study is a proof of concept mechanistic study that will utilise a combination of prebiotic and probiotic (synbiotic) supplements.
- Trial name
- NCT06480812
- Testing
- Synbiotic
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Elizabeth Simpson
Constipation
Probiotic Improve Constipation
To evaluate the efficacy and safety of probiotic as a food supplement in regulating bowel habits in patients with chronic constipation, and to compare it with placebo.
- Trial name
- NCT07462481
- Testing
- Probiotic, High-activity probiotic probiotic
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity
Effect of Probiotics on Regulating Gut Health and Blood Lipid in Adults
The purpose of this study was to evaluate the efficacy of 1 capsules (300 mg per capsule) of Nutrarex Probiotic Capsules per day in regulating gut health and blood lipid in adults by clinical trial.
- Trial name
- NCT06554314
- Testing
- probiotics
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Eczema, Allergy
Probiotics in Prevention of Allergies, Obesity and Caries
During the period of 2000-2003, 179 healthy, term infants with no previous signs of allergic disease were recruited and randomized to daily intake of cereals with or without the addition of Lactobacillus paracasei subspecies…
- Conditions
- Eczema, Allergy, Asthma, Obesity
- Trial name
- ELEFANT (NCT00894816)
- Testing
- Lactobacillus F19
- Where
- Sweden
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Umeå University
Healthy
Followup of Infants Fed Non-routine Infant Formula
The purpose of this study is to compare physical development of infants fed one of three study formulas.
- Trial name
- NCT00665938
- Testing
- Infant formula
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Mild Gastrointestinal Symptoms in Healthy Adults
BacterioPHAGE for Gastrointestinal Health 2 Study
The BacterioPHAGE for Gastrointestinal Health-2 study is designed to determine if a commercial bacteriophage product can increase the survival and efficacy of probiotic bacteria that will be concurrently administered.
- Trial name
- PHAGE2 (NCT04511221)
- Testing
- Bifidobacterium animals subsp. lactis BL04+PreforPro, Bifidobacterium animals subsp. lactis BL04
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Iron-deficiency, Iron Deficiency Anemia
Improving the Iron Status of Athletes With Pre-, Pro- and Synbiotics
Iron deficiency (ID) is the most common micronutrient deficiency worldwide, and poor iron bioavailability is a major cause. While 30% of female athletes are affected by ID, and its consequences are highly relevant to athletic…
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
- Trial name
- NCT06021171
- Testing
- Partially hydrolyzed guar gum + bifidobacterium lactis, Partially hydrolyzed guar gum, Maltodextrin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College
Viral Infections of the Upper Respiratory Tract
Probiotics in Prevention of Common Cold
The objective of this study is to assess the benefit and tolerability of a probiotic product in subjects with increased susceptibility to common cold.
- Trial name
- NCT02013934
- Testing
- Probiotic
- Where
- Germany
- Volunteers
- 899 people, healthy volunteers welcome
- Sponsor
- Probi AB
Dental Caries
Povidone Iodine for Caries Prevention
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1.
- Trial name
- NCT07741409
- Testing
- Povidone Iodine 5% Soln,Top,Kit, Probiotics
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Jeffrey A. Banas
Healthy Participants
Impact of Supplementation of Probiotics and Grape Marc on Psychological Well-being of Healthy Adults
An open-label, baseline-controlled (pre-post) pilot study to assess the maintenance and/or improvement of both physical and mental well-being in subjects who daily consume either a food supplement or a functional food containing…
- Trial name
- Rescue-bio (NCT07265934)
- Testing
- Probiotic bars, Probiotic capsules
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Synbiotec Srl
Antibiotic-associated Diarrhea
Mechanisms of Preventing Antibiotic-Associated Diarrhea and the Role for Probiotics
The focus of the study is to better understand the mechanisms causing antibiotic-associated diarrhea (AAD) and how probiotics may prevent some of the iatrogenic effects of antibiotic medications.
- Trial name
- YOBIOTIC (NCT03755765)
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, BB-12, Control
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Acute Otitis Media
Bio-Kult Infantis® in AAD Prevention in Infants
Background: antibiotic-associated diarrhoea (AAD) is defined as an acute inflammation of the intestinal mucosa associated to the administration of antibiotics.
- Trial name
- NCT03516409
- Testing
- Biokult
- Where
- Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Probiotics International Ltd.
Acne Vulgaris, Acneiform Eruptions
The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne
The purpose of this study is to evaluates how probiotics and dietary supplementation with an herbal powder can shift the gut microbiome in those with non-cystic acne vulgaris.
- Conditions
- Acne Vulgaris, Acneiform Eruptions, Skin Diseases, Sebaceous Gland Diseases
- Trial name
- NCT05919810
- Testing
- Probiotic, Oral herbal powder supplement
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Potential Abnormality of Glucose Tolerance, Appetite Disorders
Acute Effects of Juice Consumption With Biofunctional Compounds and Probiotics on Glucose Metabolism
This study investigated the short-term effects of fruit juice enriched with Vitamin D3 or n-3 PUFA or probiotics and the combination of the three ingredients on glucose metabolism.
- Trial name
- NCT05702359
- Testing
- Glucose as reference food, Control juice, Juice with vitamin D3
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Healthy Volunteers
Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota
The purpose of this study is to compare and contrast the effects of the probiotic Saccharomyces boulardii, the antibiotic amoxicillin/clavulanate and the combination on the gut microbiota of healthy volunteers.
- Trial name
- NCT01473368
- Testing
- Saccharomyces boulardii, Amoxicillin Clavulanate
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Gingivitis
Effect of Probiotics on Oral Homeostasis During Oral Hygiene Discontinuation
The present study is a double-blinded randomized clinical trial with a duration of 28 days.
- Trial name
- NCT05268757
- Testing
- Oral hygiene discontinuation
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontal Diseases
The Role of Probiotics in Periodontal Disease
In this randomized controlled trial, it was aimed to evaluate the effect of probiotics (chewable tablets) and kefir consumption in the initial periodontal treatment of periodontitis patients on the change of oral microbiota and…
- Trial name
- tropipd (NCT05211219)
- Testing
- Probiotics, AOÇ Kefir, Food without additional food supplements
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gazi University
Influenza
Evaluation of the Safety and Effectiveness of a Probiotic Bacterium to Boost the Immune Response to Influenza Vaccines
This project aims to test the hypothesis that oral consumption of a specific strain of the probiotic bacterium Lactobacillus fermentum (trademarked PCC®) is able to significantly enhance the immune response to a vaccine for…
- Trial name
- NCT00294788
- Testing
- Fluvax, PCC® (Lactobacillus fermentum VRI 003)
- Where
- Australia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Probiomics Ltd
Lactobacillus Infection
Treatment of the Intermediate Vaginal Microbiota With Vaginal Lactobacillus Casei Rhamnosus to Improve Pregnancy Outcome
In the currently presented trial, investigators aim to evaluate the treatment of the intermediate vaginal microbiota during the first trimester of pregnancy with vaginal lactobacilli to restore the normal vaginal microbiota and…
- Trial name
- LCR35&PTD (NCT02979288)
- Testing
- Lactobacillus casei rhamnosus (Lcr 35 regenerans), NO Intervention
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
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