Clinical trials: Probiotic
Osteoporosis
Symbiotic Yogurt, Calcium Absorption and Bone Health in Young Adult Women
Prebiotics have been linked to increased calcium absorption in animal and human studies (particularly in adolescents and in premenopausal women).
- Trial name
- NCT03420716
- Testing
- yogurt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad de la Republica
Dental Caries
Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children
The primary objective of this trial is to investigate the effect of a symbiotic lozenge on dental caries in young children.
- Trial name
- PiP-C (NCT03928587)
- Testing
- 2 billion CFU in total of the two strains Lactobacillus paracasei subsp. paracasei and Lactobacillus rhamnosus and arginine.
- Where
- Denmark
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Bacterial Vaginosis, Candidosis Vaginal
Lacticaseibacillus Rhamnosus CA15 (DSM 33960) Strain as a New Driver in Restoring the Normal Vaginal Microbiota
The aim of the present randomized double-blind placebo-controlled trial is to evaluate the efficacy of a probiotic formulation, containing the probiotic strain Lacticaseibacillus rhamnosus CA15 (DSM 33960), in the treatment of…
- Conditions
- Bacterial Vaginosis, Candidosis Vaginal, Urinary Tract Infections
- Trial name
- NCT05796921
- Testing
- Lacticaseibacillus rhamnosus CA15 (DSM 33960) probiotic strain
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Agnese Maria Chiara Rapisarda
Healthy
An Intervention on Healthy Adults of Probiotics on Gut Flora Metabolisms of Choline
The aim of the study is to examine the effects of probiotics intervention on choline metabolites and intestinal microbiota composition using a randomized double blind clinical trial.
- Trial name
- NCT03292978
- Testing
- probiotics intervention, non-probiotic control
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Overweight and Obesity
The Effect of Supplementation With Species of Lactobacillus on Anthropometric Measurements
The investigators aimed to study the effect of supplementation with species of Lactobacillus on anthropometric measurements, body composition, appetite and serum lipid profile in overweight and obese adults
- Trial name
- NCT02448940
- Testing
- Species of Lactobacillus, lactose
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Urmia University of Medical Sciences
IBS - Irritable Bowel Syndrome, Diarrhea
A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients
The goal of this interventional clinical study is to study whether the consumption of QiMeiYan Probiotics in 25-35 young people with Mild irritable bowel syndrome (IBS Score 75 - 175) will reduce the frequency of Diarrhea.
- Trial name
- NCT05900752
- Testing
- QiMeiYan Probiotics
- Where
- 2 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shenzhen Precision Health Food Technology Co. Ltd.,
Microbial Colonization, Nutrient Deficiency
Effect of Nutrition Training on Mothers' Nutrition Pattern, Breast Milk and Newborn Intestinal Microbiota
Objective: The aim of this study was to investigate the effects of nutrition Training on mothers' nutrition pattern, breast milk and newborn intestinal microbiota.
- Trial name
- microbiota (NCT04223375)
- Testing
- Nutrition Training
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Plaque
Effect of Probiotic Toothpaste and Regular Toothpaste on Plaque Levels of Orthodontic Patients
This study is set to determine the improvement in plaque levels utilizing Plaque Index Simplified scores in orthodontic patients using probiotic toothpaste and regular toothpaste.
- Trial name
- NCT06473792
- Testing
- Probiotic Toothpaste
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Kanza Tahir
Gut Microbiota
Characterization of the Gastrointestinal Microbiota in Term Newborn Infants After 4 Weeks Supplementation of Probiotics
A mono center, open label, pilot study in term newborn infants. The study will investigate the effect of supplementation with probiotics on the presence of total Bifidobacterium in the infant feces.
- Trial name
- NCT04994834
- Testing
- Probiotics
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Non-Alcoholic Fatty Liver Disease, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Effects of Probiotics (P. Pentosaceus, L. Lactis or L. Helveticus) in NASH
A study for evaluating the improvement effect on Metabolic dysfunction-associated steatotic liver disease (MASLD) of probiotics Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with dysbiosis of the…
- Trial name
- NCT04555434
- Testing
- Probiotics
- Where
- South Korea
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Infant, Newborn, Gut -Microbiota
Infant Microbiota Restoration With Maternal Microbes
The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants.
- Conditions
- Infant, Newborn, Gut -Microbiota, Gut Dysbiosis, Cesarean Delivery Affecting Newborn
- Trial name
- MaMi (NCT07212361)
- Testing
- Probiotic
- Where
- 2 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Hashimoto Disease, Psoriasis
Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis
Hashimoto's disease (HT) and psoriasis (PsO) have a significant impact on patient's quality of everyday life, and early diagnosis is critical for the symptoms management and prognosis.
- Trial name
- METHAP (NCT04693936)
- Testing
- Nutraceutical Combination Plan
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Crete
Dental Caries
Povidone Iodine for Caries Prevention
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1.
- Trial name
- NCT07741409
- Testing
- Povidone Iodine 5% Soln,Top,Kit, Probiotics
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Jeffrey A. Banas
Nutrition, Healthy
Effect of L. Plantarum Probiotic Supplementation on Broccoli Sulforaphane Bioavailability: Randomised Double-blind Placebo-controlled Crossover Study
Broccoli has the precursor of an active compound (sulforaphane) that has shown a wide range of health promoting benefits. Sulforaphane formation depends on the conversion of glucoraphanin (precursor) by myrosinase enzyme.
- Trial name
- PRO-BROC (NCT06561893)
- Testing
- Broccoli sprouts extract supplementation
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Gut, Microbiota Balance
Efficacy Study of the Probiotic Food Supplement PROBAFLOR for Maintaining Intestinal Well-being
It is now known that intestinal health has a strong influence on the entire body. Recent research advances have demonstrated the involvement of the intestinal microbiota in the well-being of the intestine.
- Trial name
- PROBAFLOR (NCT06619067)
- Testing
- PROBAFLOR
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Synbiotec Srl
Recurrent Kidney Stones With Colicky Pain
A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic. Supplementation in Reducing the Risk of Kidney Stone in Adults With Recurrent Kidney Stone Colic or Acute Episode of Colicky Pain.
A Preliminary Investigation of the Safety and Effectiveness of Oral Probiotics Supplementation for Reducing the Risk of Kidney Stone in Adults with Recurrent Kidney Stone Colic or Acute Episode of Colicky Pain: An Open-Label…
- Trial name
- NCT06477471
- Testing
- MetProrenes
- Where
- India
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Inflammatory Bowel Diseases
Effect of Yogurt Added With Bifidobacteria and Soluble Fiber on Bowel Function.
The aim of this study was to evaluate the effect of the consumption of yogurt added with bifidobacteria and soluble fiber on gastrointestinal function of healthy adults.
- Trial name
- NCT01173588
- Testing
- yogurt added with bifidobacteria and soluble fiber (YBF)
- Where
- Mexico
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Instituto Lala
Mandibular Prosthesis User
Assessment of the Impact of Probiotics on Biofilm Formation on Removable Acrylic Dentures
The aim of this study is to evaluate the effect of PIP toothbrush cleaner® on the microbial composition and Candida albicans colonization of denture biofilm formation.
- Trial name
- NCT02736994
- Testing
- PIP toothbrush cleaner® (Chrisal, Lommel, Belgium)., Corega Tabs Anti-bacteria®, Water
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sport Nutrition, Probiotic
Supplementation With GKEX Sports Probiotic Combo for Muscle Gain and Fat Loss Assessment
Objective: To discuss the "GKEX Sports Probiotics Combination (hereinafter referred to as GKEX)", a product commissioned by Grape King Biotechnology Co., Ltd., and its effects on increasing muscle mass, muscle strength, physical…
- Trial name
- NCT05909475
- Testing
- GKEX
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
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