Clinical trials: Probiotic
Permeability; Increased
PRObiotic and Stress-related PERmeability
This is a single-site exploratory study aiming to demonstrate the effect of a fresh fermented dairy drink containing a probiotic strain on stress-related intestinal hyperpermeability in students defending a bachelor's or master's…
- Trial name
- ProSPer (NCT03408691)
- Testing
- Fresh fermented dairy drink containing probiotic strain, Acidified dairy drink without ferment
- Where
- Belgium
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Muscle Weakness
The Effect of GI Biome #7 on Gut Microbiome and Health of the Elderly
This study aims to investigate the effects of probiotics named GI Biome #7 on the gut microbiome and muscle strength in older adults aged 60 years or older.
- Trial name
- NCT05735418
- Testing
- GI Biome #7
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Obesity
Exercise, Milk Thistle, and Lactobacillus to Influence Plasma Bilirubin
The proposed clinical trial will test our hypothesis that, during exercise, red blood cell (RBC) release of heme and catabolism to bilirubin is an essential process that mediates gene responses that reduce body fat.
- Trial name
- NCT04717726
- Testing
- Milk Thistle (MT), Lactobacillus Gasseri (LAC), Exercise (EX)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kyle Flack
Main Focus: Gluten and Starch Digestibility
GlutDigest - Pilot Study
This is a pilot, feasibility study to evaluate, test and optimize sample analysis procedures and protocols before the full-scale, crossover study is conducted.
- Trial name
- GlutDigestP (NCT04489836)
- Testing
- Glutalytic®, DE111®, Meal A
- Where
- Ireland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Microbial Colonization
Study of Human Microbiota in Healthy and Pathological Conditions
The aim of the present study is to characterize the bacterial composition (microbiota) colonizing to the human body in different physio - pathological conditions (lifestyle, motor activity, surgical operations, probiotic and…
- Trial name
- MicroSP (NCT03460392)
- Testing
- Antibiotic therapy
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Inattentive, Hyperactivity
Assessment of Probiotics Lactobacillus in the Management of Attention Deficit Hyperactive Disorder
ADHD is a neurodevelopmental disorder characterized by persistent symptoms of inattention and/or hyperactivity and impulsivity that are present before age 18.
- Conditions
- Inattentive, Hyperactivity, Impulsivity
- Trial name
- ADHD (NCT04167995)
- Testing
- Probiotic Formula lacteal forte
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Irritable Bowel Syndrome
Efficacy of a Probiotic Blend to Reduce Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a recurrent, functional disorder characterized by abdominal pain and discomfort, changes in bowel habits and gastrointestinal symptoms such as distension and sensation of abdominal inflammation…
- Trial name
- NCT05819281
- Testing
- Probiotic blend
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Gastrointestinal Diseases
Probiotics Improve Health Young Volunteers' Gut Microbiota
The goal of this clinical trial is to evaluate whether daily supplementation with the probiotic Bifidobacterium breve BBr60 can improve metabolic, gastrointestinal, and emotional health in healthy adult volunteers aged 19 to 45…
- Trial name
- NCT06196892
- Testing
- Probiotic BBr60
- Where
- China
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
VOLUNTEERS
Lactobacillus Plantarum 3547 Effects Over Inflammatory and Immunologic Markers
The purpose of this study is to evaluate the effects of the probiotic Lactobacillus plantarum 3547 over different inflammation and immune system markers on a healthy middle-aged group.
- Trial name
- NCT02622867
- Testing
- Lactobacillus plantarum 3547, Maltodextrin
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Dietary Supplement
Probiotics in Children With Early Childhood Caries
The purpose of this study is to determine if probiotic lozenges taken once a day before bedtime for twelve weeks can decrease the numbers of Streptococcus mutans
- Trial name
- NCT03998306
- Testing
- Experimental: Probiotics, No intervention
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Gastrointestinal Tract Flora Composition
Effect of Probiotics on the Digestibility and Immunity in Infants
The purpose of this study is to evaluate the effect of the probiotic product on the GI tract flora composition.
- Trial name
- NCT02317406
- Testing
- Biostime probiotics sachet children's formula
- Where
- China
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Biostime Institute of Nutrition and Care
Undernutrition
Fortified Milk, Growth and Micronutrient Status in Mexican Toddlers (MilkGrowth)
The objective of the present study was to assess the effect of a growing-up milk on growth and micronutrient status in children 12 to 30 months of age. The study was conducted in Cuernavaca, the state capital of Morelos, Mexico.
- Trial name
- NCT03397485
- Testing
- Growing milk, Fortified milk
- Where
- Mexico
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Depressive Disorder, Major
Probiotics and the Gut Brain Axis- Do Probiotics Interact With the Vagal Nerve?
The purpose of this study is to investigate the effects of a multispecies probiotic on the function of the vagal nerve in patients with major depression and healthy participants in a single-center, randomized, placebo-controlled…
- Trial name
- ProBIO-HRV (NCT04772664)
- Testing
- Multispecies-Probiotic
- Where
- Austria
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Type1diabetes, Type1 Diabetes Mellitus
Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics
Investigators aim to further the understanding of environmental factors that underlie the progression to Type 1 diabetes (T1D). Dysbiosis, defined as alterations in intestinal microbiota composition and function, has been…
- Trial name
- NCT03423589
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Microbiome
Effect of a Probiotic or Postbiotic on Gut Microbiome During Antibiotic Treatment
This study assesses the effects of a probiotic or postbiotic on gut microbiome during antibiotic treatment.
- Trial name
- POTATO-2 (NCT07594860)
- Testing
- Probiotic, Postbiotic
- Where
- Greece
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Obesity, Insulin Resistance
Targeting the Gut Microbiome to Investigate the Pathways of Progression From Obesity to Metabolic Diseases in an At-risk Population.
Studies of the human gut microbiome have suggested that treatment or prevention aimed at the obese microbiome could influence the development of obesity-associated metabolic disturbances.
- Trial name
- NCT01433120
- Testing
- Lactobacillus paracasei ssp paracasei F19, Flax seed fibres
- Where
- Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Probiotic, Microbiota
Effect of a Probiotic on Microbiota Associated with the Immune System and Inflammation.
The goal of this randomized clinical trial is to learn about the effect of consuming a probiotic on the microbiota associated with immune health and inflammation in healthy women and men after 6 weeks of intervention.
- Trial name
- FLORABIOTIC (NCT06313346)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Healthy
Growth of Infants Fed a New Term Infant Formula
To evaluate the growth of healthy term infants fed an experimental infant formula with a prebiotic, a commercial control infant formula with a probiotic, but without a prebiotic and human breast milk
- Trial name
- NCT03090360
- Testing
- Infant formula (CF), Infant Formula (EF)
- Where
- 7 sites in Belgium, Italy
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Congenital Diaphragmatic Hernia
Microbiome and Volatile Organic Compounds in Patients With CDH
Despite improved prenatal diagnostics and therapeutic possibilities, congenital diaphragmatic hernia (CDH) represents a cross-disciplinary challenge.
- Trial name
- CDHVOCS (NCT03787160)
- Testing
- initial VOC, initial fecal microbiome, initial pulmonary microbiome
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Oral Health, Oral Disease
Levilactobacillus Brevis Oral Health
This RCT investigates the impact of an oral supplement containing the probiotic Levilactobacillus brevis CNCM I-5566 on various salivary indicators of oral health.
- Trial name
- LBOH-RCT (NCT06457724)
- Testing
- Levilactobacillus brevis CNCM I-5566
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
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