Clinical trials: Probiotic
Osteoporosis, Obesity
Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian Young Adults
Milk and dairy products contain significant amounts of nutrients that contribute to optimal health - nutrients like calcium, vitamin D, and high-quality protein.
- Trial name
- NCT06265246
- Testing
- Habitual Diet + Milk, Habitual Diet + Yogurt
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Overweight or Obesity
Probiotic Influence on Obesity-Related Lipidemia
This study aims to investigate the effects of Bifidobacterium breve BBr60 on key health indicators in overweight and obese adults.
- Trial name
- NCT06305650
- Testing
- Probiotic
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Atopic Dermatitis
Study of the Skin Microbiome and the Potential of a Topical Probiotic Cream for Atopic Dermatitis
The skin microbiome of atopic dermatitis patients and healthy volunteers will be studies by collecting and analysing skin swabs on different timepoint.
- Trial name
- NCT04771910
- Testing
- Topical cream with live probiotic bacteria
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Transmission
Baby 2 Baby Beneficial Bacteria
The investigators will recruit mother-infant dyads to attend weekly lactation support groups and randomize infants to receive either an HMO consuming or non-HMO consuming probiotic.
- Trial name
- NCT05703659
- Testing
- B. longum subsp. infantis, L. reuteri probiotic
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Clostridium Difficile Infection Recurrence
Bacillus Velezensis DSM 33864 for Reduction of the Risk of Recurrent Clostridioides Difficile Infections
The purpose of this study is to determine whether a single strain capsulated probiotic, when used after standard C. difficile antibiotic therapy, is effective in reducing the risk of infection recurrence mediated by a decrease in…
- Trial name
- NCT05606159
- Testing
- Bacillus velezensis DSM 33864
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novozymes A/S
Dental Plaque
Probiotic Lactobacillus Reuteri and Oral Microbiota
In February 2013, 44 healthy adults was recruited and randomized to daily intake of lozenges with or without Lactobacillus reuteri strains DSM 17938 and PTA 5289 for 12 weeks.
- Trial name
- OMICI (NCT02311218)
- Testing
- Lactobacillus reuteri DSM 17938 and PTA 5289
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Umeå University
Irritable Bowel Syndrome
Manipulation of Visceral Sensitivity and Immune System in IBS
Irritable bowel syndrome (IBS) is a common condition. At least 20% of the population suffer from IBS. The symptoms of abdominal pain, diarrhoea, constipation, bloating and difficulty with bowel motions are often disabling.
- Trial name
- NCT00418340
- Testing
- probiotic (bacterial/dietary supplement)
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Parkinson Disease, Movement Disorders
Multimodal Image Technologies Investigate the Role and Mechanism of Probiotics in Improving RBD with Parkinson's Disease
Rapid eye movement sleep behavior disorder (RBD) is important non-movement feature, and also the important risk factor of Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Movement Disorders, Rapid Eye Movement Sleep Behavior Disorder, Gut Microbiomes
- Trial name
- NCT06710574
- Testing
- PD-RBD, iRBD
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Menstrual Discomfort
Probiotic and Gastrointestinal Symptoms Due to Menstruation in Healthy Women
In this double blind, parallel study, female participants who are on an oral contraceptive will consume either a probiotic or placebo supplement for approximately 8 weeks.
- Trial name
- NCT04457401
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Florida
Weight Loss
Use of Probiotics to Aid in Weight Loss
The purpose of this study is to evaluate the success of daily supplementation of multiple probiotic bacterial cultures over 12 weeks in increasing the percentage of excess weight loss in the RNYGB (Gastric Bypass) weight loss…
- Trial name
- Probiotics (NCT01445704)
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Healthy Infants
To Investigate Effects of a New Infant Formula in Healthy Term Chinese Infants
This study investigates the effects of a new infant formula on growth, safety, and tolerance in healthy term Chinese infants. Screening starts after the informed consent is obtained.
- Trial name
- NCT03520764
- Testing
- New infant formula with synbiotics, Standard infant formula with prebiotics
- Where
- 6 sites in China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Danone Nutricia
Semen Quality
The Impact of Probiotics on Sperm Quality in Middle-aged Men
The clinical trial aims to investigate the impact of probiotic strain BL21 on sperm quality among 46 middle-aged male participants.
- Trial name
- NCT06544278
- Testing
- probiotic product, Maltodextrin
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Air Travel
The Impact of Air Travel on Passenger Cognitive Functions
In the period from June 2021 to June 2022, a prospective clinical study will be conducted in the Republic of Kazakhstan with economy class passengers traveling by plane with a minimum flight period of 5-7 flight hours in the…
- Trial name
- NCT04802785
- Testing
- Citicoline, Cytochrome C6, Sodium Chloride Oral Product
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dinara Zhumanbayeva
Exercise Performance
Effects of Probiotics Improves the Endurance and Explosiveness Exercise Performance on Healthy Human.
This study may discover that supplementing with probiotics LY-66, PL-02 can promote exercise endurance, explosive power and reduce muscle inflammation index in healthy people.
- Trial name
- NCT06092723
- Testing
- Probiotic 1,Lactococcus lactis subsp. lactis, LY-66, Probiotic 2,Lactobacillus plantarum, PL-02, Probiotic 3,Lactococcus lactis subsp. lactis, LY-66+Lactobacillus plantarum, PL-02
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Glac Biotech Co., Ltd
Photobiology
Placebo-controlled Assessment of the Effect of a Food Supplement on Skin Protection After Exposure to UV Radiation
A probiotic bacterial strain was tested in a randomized, double blind , placebo controlled clinical trial with 54 healthy male volunteers.
- Trial name
- NCT00351689
- Testing
- dietary supplement
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Infant Gut Microbiome
The EFFECT Study: Probiotic and HMO Supplementation in Infants
Lacto-N-tetraose (LNT) is a human milk oligosaccharide (HMO) present in human colostrum and milk. HMOs are largely undigestable and have no direct nutritive benefit to the infant, but act as a prebiotic substrate for beneficial…
- Trial name
- EFFECT (NCT03994315)
- Testing
- B. infantis EVC001, Lacto-N-tetraose (LNT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Evolve BioSystems, Inc.
Mucositis, Peri-implantitis
Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis
Evaluate clinically and microbiologically the effect of the oral probiotic Lactobacillus reuteri Prodentis (PerioBalance®, Sunstar, Switzerland) on implants with mucositis or periimplantitis, as a coadjuvant treatment of…
- Trial name
- NCT03047291
- Testing
- Probiotic
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Urinary Tract Infections
Open Label Trial of Nissle 1917
Nissle 1917 is an E. coli based probiotic used in the Europe for close to 100 years to treat gastrointestinal disorders and infections.
- Trial name
- NCT02276508
- Testing
- E. coli Nissle 1917
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Elizabeth Lucas
Healthy Subjects With Fixed Orthodontics
The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.
In this study, researchers will test the effectiveness of probiotic consumption against oral pathogenic bacteria and reduce the occurrence of gingival inflammation in subjects using orthodontic fixed appliances (braces).
- Trial name
- NCT04847960
- Testing
- BioGaia Probiotic Lozenges
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Trisakti University
Functional Constipation
A Study to Assess the Effect of the Bio-K+ Probiotic Capsules (VL-BK-02) in Adults With Functional Constipation
The present study is a randomized, placebo-controlled, double-blind, parallel-group clinical study designed to assess the effects of IP in individuals with Functional constipation as compared to a placebo.
- Trial name
- NCT06730594
- Testing
- VL-BK-02 (25 billion CFU/Capsule)
- Where
- 6 sites in India
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
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