Clinical trials: Psilocybin
Chronic Low Back Pain (CLBP), Physical Therapy
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
The purpose of this research study is to investigate whether a single administration of psilocybin can improve interoceptive awareness (awareness of bodily sensations) in individuals with chronic low back pain undergoing physical…
- Conditions
- Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
- Trial name
- NCT07306364
- Testing
- Psilocybin 10 mg, Psilocybin 25 mg, Niacin 100 mg
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness
Psilocybin (active compound of "magic mushrooms") is a prototypical psychedelic substance that acts via agonism on serotonin (5-HT) 2A receptors. Psilocybin is rapidly metabolized into its active metabolite psilocin.
- Trial name
- PDR (NCT06796361)
- Testing
- Ketanserin 40mg plus Psilocybin 40mg, 40mg Psilocybin, 20mg Psilocybin
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Amnestic Mild Cognitive Impairment
Does Psilocybin Change Synaptic Density in Amnestic Mild Cognitive Impairment
The goal of this pilot, exploratory, clinical trial is to investigate the effects of psilocybin on synaptic vesicular density (SVD) as measured by the positron emission tomography (PET) radiotracer, 18F-SynVesT-1, in participants…
- Trial name
- NCT06041152
- Testing
- Psilocybin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health