Clinical trials: Transcranial Direct Current Stimulation
Drug Addiction
The Cognitive Neural Mechanisms and Neuroregulatory Interventions of Realistic Creative Problem-solving Under the Effects of Drug Addiction
Drug addiction persists as a significant global social concern with a negative impact on social harmony and stability that cannot be ignored.
- Trial name
- NCT06917534
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yifan Wang
Drug Addiction
Project on tDCS Intervention to Enhance Advanced Social Cognitive Functions in Drug Rehabilitation Individuals
This project aims to explore key brain functional and biochemical indicators associated with impaired advanced social cognition through an integrated approach encompassing unconscious control, conscious control, cognitive…
- Trial name
- NCT06888700
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Shaanxi Normal University
Healthy
Effect of Electrical Stimulation (DC Polarization) to the Brain on Memory
This study will test the effect of direct current (DC) brain polarization (the application of a very weak electrical current to the brain) on learning and memory.
- Trial name
- NCT00471107
- Testing
- DC brain polarization
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sleep, Sleep Hygiene
Electrical Synchronization of Slow Oscillations to Enhance Deep Sleep
This study applied slowly oscillating (0.5 hz) transcranial electrical stimulation (TES; frontopolar and lateral frontal electrodes versus mastoid and occipital electrode returns) to synchronize the endogenous slow oscillations…
- Trial name
- ESSOTEDS (NCT04461769)
- Testing
- Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Brain Electrophysiology Laboratory Company
Stroke, Aging
Enhancing Sleep Dependent Consolidation by Non-invasive Brain Stimulation
Stroke, one of the most common causes for acquired adult disability, is not only a burden for the individual but also for his or her close relatives and caregivers.
- Trial name
- E-ConS (NCT05843656)
- Testing
- Non-invasive brain stimulation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Friedhelm Hummel
Pain, Transcranial Direct Current Stimulation
Transcranial Versus Suboccipital Direct Current Stimulation
Randomized controlled trial, in parallel with cross-control design. Two groups of healthy subjects will be randomly selected to transcranial stimulation group or suboccipital stimulation group.
- Trial name
- NCT04117256
- Testing
- Direct Current Stimulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Pain Modulation
Evaluation of the Hypoalgesic Effects of Transcranial Direct Current (tDCS) in Healthy Subjects
The main objective of this research is to evaluate and quantify hypoalgesic effects caused by imagination and observation with or without the presence of transcranial direct current (tDCS) in healthy participants.
- Trial name
- NCT04127253
- Testing
- Sooma transcranial direct current stimulation device plus Brain training tools, Brain training tools in isolation
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Aging
CONTROL Walking Study
Older adults often experience substantial deficits in walking ability, especially for walking tasks that are more complex such as obstacle crossing.
- Trial name
- NCT03790657
- Testing
- practice of a complex walking task, Active transcranial direct current stimulation (Active tDCS)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dysphoria
Effects of Transcranial Direct Current Stimulation on Reward Learning in Subclinical Depression.
This project will test whether transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) can alter reward learning behaviour in subclinical depression.
- Trial name
- NCT03393312
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Aging, Mild Cognitive Impairment
Implication of Cognitive Reserve in Non-pharmacological Intervention Outcomes
Cognitive reserve (CR) is defined as the gradual accumulation of neural resources and their adaptability (i.e., efficiency, capacity, flexibility) due to genetic and/or lifelong environmental factors that mitigate the cognitive…
- Conditions
- Aging, Mild Cognitive Impairment, Dementia With Lewy Bodies
- Trial name
- NCT06563453
- Testing
- transcranial alternating current stimulation
- Where
- Czechia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Inflammatory Bowel Diseases
Transcranial Direct Current Stimulation and the Interaction Between Chronic Pain and the Intestinal Epithelial Barrier in Patients With Chronic Inflammatory Bowel Diseases (IBD)
In the study the investigators aim to test whether transcranial direct current stimulation (tDCS) induced pain reduction is in association with functional changes in the brain measured with magnetic resonance imaging (MRI) and…
- Trial name
- NCT03825900
- Where
- Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cerebral Palsy, Perinatal Stroke
Single-session tDCS in Cerebral Palsy
The goal of this study is to characterize individual responses to a single application of transcranial direct current stimulation (tDCS) in children with unilateral cerebral palsy (UCP), and to test which electrode configuration…
- Conditions
- Cerebral Palsy, Perinatal Stroke, Periventricular Leukomalacia
- Trial name
- NCT03635775
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Parkinson Disease
The Effect of tDCS on a Motor-cognitive Dual-task Performance of Parkinson's Patients
The concurrent performance of two tasks, i.e., dual tasking (DT), is a common and ubiquitous every day phenomena. For example, people frequently walk while talking on a cellphone or drive while talking to a passenger.
- Trial name
- NCT02503930
- Testing
- Active tDCS
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Young Adults
Inhibitory Control: Effects of Modulation
Inhibitory control is relevant to many clinical disorders, including substance abuse/dependence, obsessive-compulsive disorder, and attention-deficit hyperactivity disorder.
- Trial name
- NCT04247334
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Frontotemporal Dementia
Gamma-Induction in FrontoTemporal Dementia Trial
This is an interventional, sham controlled, double-blind study designed to investigate the safety, tolerability and efficacy of 40 Hz transcranial alternating current stimulation (tACS), a form of noninvasive brain stimulation…
- Trial name
- GIFTeD (NCT04425148)
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- 2 sites in United States, Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neurosurgery
Neurosurgical Skill Enhancement Using Transcranial Stimulation
Recent changes in medical training environments and restrictive work-hour regulations have greatly impacted trainees, limiting the number of opportunities to gain proficiency in procedural skills.
- Trial name
- LETS-LEARN (NCT02987816)
- Testing
- Anodal tDCS
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Acute Postoperative Pain
Effects of tDCS and VNS on Postoperative Analgesia
This study seeks to evaluate the efficacy of transcranial direct current stimulation (tDCS) and Afferent Vagus nerve simulation (VNS) in treating acute postoperative pain of patients in the post-anesthesia care unit after general…
- Trial name
- NCT06554067
- Testing
- Active transcranial direct current stimulation, Active vagus nerve stimulation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy Subjects
Effects of Brain Stimulation During Daytime Nap on Memory Consolidation in Younger, Healthy Subjects
The beneficial effect of daytime sleep on memory consolidation has been shown in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent declarative…
- Trial name
- NCT01840865
- Testing
- brain stimulation, no stimulation
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Aging
Neural Underpinnings of Turning
Older adults and stroke survivors often have difficulty performing complex walking tasks, due in part to changes in the brain. One task often overlooked is turning, which can lead to injury when performed poorly.
- Trial name
- NCT05475236
- Testing
- Experimental: Locomotor Learning
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Transcranial Direct Current Stimulation, Healthy Adults
Effects of HD-tDCS During Slow-wave Sleep on Associative Memory
To evaluate the effects of afternoon naps and high-definition transcranial direct current stimulation (HD-tDCS) over the left dorsolateral prefrontal cortex (DLPFC) in associative memory (AM)
- Trial name
- NCT07063264
- Testing
- high-definition transcranial direct current stimulation (HD-tDCS)
- Where
- China
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- WANG KAI