Clinical trials: Transcranial Direct Current Stimulation
Drug Addiction
The Cognitive Neural Mechanisms and Neuroregulatory Interventions of Realistic Creative Problem-solving Under the Effects of Drug Addiction
Drug addiction persists as a significant global social concern with a negative impact on social harmony and stability that cannot be ignored.
- Trial name
- NCT06917534
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yifan Wang
Tobacco Abuse Smoke
Effect of the Transcranial Direct Current Stimulation (tDCS) on Dependent Smoking People
The purpose of this study is to evaluate the effect of 10 sessions of anodal transcranial Direct Current Stimulation (tDCS - 1 mA) applied to left vs right CDLPF of tobacco-dependent subjects compared to the application of a…
- Trial name
- TabaSCo (NCT02867514)
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Major Depression, Functional Dyspepsia
The Brain-Heart-Gut Connection
Major Depressive Disorder (MDD) often co-occurs with cardiovascular and gastrointestinal symptoms, highlighting the importance of the brain-heart-gut connection in developing comprehensive treatments.
- Conditions
- Major Depression, Functional Dyspepsia, Autonomous Dysfunction
- Trial name
- BHG-CONNECT (NCT06748274)
- Testing
- Transcranial Magnetic Stimulation (TMS), High-definition transcranial direct current stimulation (HD-tDCS)
- Where
- Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Bern
Aging
Modulating Brain Activity to Improve Goal-directed Physical Activity in Older Adults
Although the majority of older adults are aware of the compelling evidence that regular exercise is critical to the maintenance of health into old age, most do not meet recommendations for daily exercise.
- Trial name
- Stim-Fit (NCT04278560)
- Testing
- Transcranial direct current stimulation (tDCS), Behavioral intervention to increase physical activity
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Healthy Volunteers, Motivation
Neural Bases of Motivation
Effort-based decisions are essential in daily life but strongly impaired in apathy across various brain disorders. Now, significant research to unveil the neural causes of apathy is needed.
- Conditions
- Healthy Volunteers, Motivation, Action
- Trial name
- MOTIVACTION (NCT07251816)
- Testing
- Cortico-cortical paired-associative stimulation (ccPAS), Bifocal transcranial alternating current stimulation (tACS), Combining transcranial temporal interference stimulation (tTIS) and oscillatory TMS
- Where
- France
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Antisocial Behavior, Aggression
The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
This study investigates the relationship between prefrontal cortex activity and antisocial and aggressive behavior, and risk factors for such behavior.
- Trial name
- NCT02674516
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Non-restorative Sleep, Healthy Volunteer
Power Nap With TES-TI
The goal of this clinical trial is to find out whether stimulating the brain with electrical current during naps can increase certain kinds of brain activity that happen during sleep and lead to improvements in mental fatigue.
- Trial name
- NCT07090135
- Testing
- Transcranial electrical stimulation with Temporal Interference (TES-TI)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aging, Mild Cognitive Impairment
tDCS and Cognitive Efficiency in Ageing
Normal aging is associated with a progressive decline in cognitive functions, especially memory. This decline in cognitive function can negatively impact the quality of life of older adults.
- Conditions
- Aging, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- FRtDCS (NCT05216315)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Healthy Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Younger, Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01832740
- Testing
- brain stimulation
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cerebral Microangiopathy, CADASIL
Impact of tDCS on Cerebral Autoregulation
The aim of the study is to investigate whether there is a polarity-specific influence of tDCS on cerebral vasomotor reactivity monitored by transcranial doppler sonography.
- Conditions
- Cerebral Microangiopathy, CADASIL, Migraine With Aura, ICA Stenosis
- Trial name
- NCT01865604
- Testing
- Anodal tDCS, Cathodal tDCS
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Semantic Dementia
Evaluation of a Transcranial Stimulation With Direct Current on Language Disorders in Semantic Dementia
Within the spectrum of fronto-temporal lobar degeneration (FTLD) semantic dementia (SD) causes profound language dysfunction. SD damages semantic processing typically in the temporal poles (anterior temporal lobes, ATL).
- Trial name
- STIM-SD (NCT03481933)
- Testing
- Transcranial stimulation
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mild Cognitive Impairment
Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation
The overall goal of this project is to improve cognitive control abilities in adults with mild cognitive impairment (MCI) through a form of non-invasive brain stimulation, transcranial alternating current stimulation (tACS).
- Trial name
- NCT04647032
- Testing
- Transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Impact of Transcranial Direct Current Stimulation Intensity on Leg Muscle Fatigability in Healthy Adults
Transcranial direct current stimulation (tDCS) is a painless,non-invasive means of increasing brain excitability. It has been used for several years and in many populations to improve physical and psychological outcomes.
- Trial name
- NCT04321304
- Testing
- Transcranial direct current stimulation at 2 mA, Transcranial direct current stimulation at 4 mA
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Electric Stimulation Therapy, Obesity
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person…
- Conditions
- Electric Stimulation Therapy, Obesity, Weight Loss, Eating
- Trial name
- NCT00739362
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Multiple Sclerosis
Efficacy of tDCS on Pain in Multiple Sclerosis
Pain is a common symptom experienced by people with MS and can significantly interfere with participation in the activities of daily living and adversely affect health-related quality of life.
- Trial name
- NCT03389217
- Testing
- Real-tDCS + rehabilitation programme
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT Gene
Mod of Cognitive Flexibility by tDCS, Tyrosine Polymorphisms in the COMT Gene
The current study would examine whether increases in endogenous dopaminergic activity via tyrosine and the (presumed) excitation of these by anodal tDCS of the dlPFC could causally be related to cognitive flexibility as measured…
- Trial name
- NCT03845920
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Transcranial Direct Current Stimulation
Effect of Transcranial Direct Current Stimulation on Flywheel Resistance Training
Transcranial direct current stimulation (tDCS) has been investigated as an ergogenic strategy; however, its acute effects on muscle power-especially when combined with flywheel resistance training (FRT)-have not yet been…
- Trial name
- NCT07831512
- Testing
- tDCS-a, tDCS-c
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Fall, Gait, Unsteady
Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait)
Walking is a complex and continuous task that entails repetitive motions of the body. Relatively high gait variability sensitively predicts falls and cognitive decline in older adults.
- Conditions
- Fall, Gait, Unsteady, Mobility Limitation
- Trial name
- NCT06008431
- Testing
- Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Basic Physiology, Brain Stimulation
Transcranial Direct Current Stimulation (tDCS) in the Primary Motor Cortex in Healthy Individuals
The main aim of this study is to assess the short-term effects of active-tDCS (a-tDCS) on the M1 regarding sensorimotor variables such as discriminative sensation, pressure pain threshold and electromyographic activity compared…
- Trial name
- NCT04148547
- Testing
- Sooma transcranial direct current stimulation device
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid