Clinical trials: Transcranial Direct Current Stimulation
Healthy
Neurophysiological Impact of a Fronto-temporal tDCS Stimulation in Healthy Subjects: a Multimodal Imaging Approach
tDCS is a technique emerging as a prospective therapy for neurologic, psychiatric and addictive disorders. Specifically, fronto-temporal tDCS, with anodal stimulation over the left dorsolateral prefrontal cortex (DLPFC) and…
- Trial name
- COMBI-STIM (NCT03056170)
- Testing
- real tDCS
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Traumatic Brain Injury
Treating Traumatic Brain Injury With Transcranial Direct Current Stimulation
Traumatic Brain Injury (TBI) often results in a wide array of cognitive impairments, which can significantly diminish quality of life for affected individuals.
- Trial name
- NCT06989970
- Testing
- Active tDCS on the DLPFC + Cognitive Intervention(s)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Older Patients, Surgery
Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery
Neurocognitive complications, mainly delirium and neurocognitive disorders, are common cerebral complications in older patients after surgery and associated with worse long-term outcomes.
- Conditions
- Older Patients, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT07576543
- Testing
- Dex-Esk, Active tDCS
- Where
- 6 sites in China
- Volunteers
- 1,996 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Subjective Cognitive Decline
Effects of Individualized Theta-tACS on a Working Memory Training at SCD
The aim of the study is to investigate the effects and mechanisms of action of an individualized transcranial alternating current stimulation in the theta-range (ITF-tACS) on a three day spatial working memory training in healthy…
- Trial name
- tACOSenior (NCT06501755)
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Transcranial Direct Current Stimulation
Mechanism and Dosimetry Exploration in TES Magnetic Resonance Current Mapping Methods
In this study the investigators will explore dosimetry in transcranial electrical stimulation using a novel magnetic resonance imaging technique that can determine how electrical stimulation distributes within the brain.
- Trial name
- TES (NCT03772210)
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Overweight and Obesity
Neuromodulation With Transcranial Direct Current Stimulation (tDCS) to Control Excess Weight
The purpose of this study is to examine the effects of noninvasive neuromodulation with transcranial direct current stimulation (tDCS) aimed at enhancing the excitability of the left prefrontal cortex in middle-aged women with…
- Trial name
- NCT03351426
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Healthy Young and Older Adults
Mechanism of tDCS-induced Learning Enhancement - the Role of Serotonin
The aim of this study is to assess whether the application of a selective serotonin reuptake inhibitor (SSRI) enhances and prolongs the learning enhancement achieved by anodal transcranial direct current stimulation (atDCS).
- Trial name
- LESO (NCT02092974)
- Testing
- tDCS, Citalopram
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Multiple Sclerosis
Assessment of tDCS-Induced Neuronal Responses in Multiple Sclerosis (MS) With Advanced MRI
The objective of this trial is to measure the changes in neural activities during tDCS session using Magnetic Resonance Imaging (MRI). Participants (N=60) (20 Healthy Controls and 40 participants with neurological disorders, ie.
- Trial name
- NCT03564496
- Testing
- tDCS Administration during MRI, Remotely-supervised Daily tDCS Administration, Optional 15 minutes of imaging + simultaneous tDCS up to 4.0mA
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alzheimer Disease
Memory Functions in Mild Alzheimer's Disease
The overall objective of this project is to examine the effects of non-invasive brain stimulation on episodic memory performance
- Trial name
- MemStim-lab (NCT04785053)
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Subjective Cognitive Decline
tDCS-enhanced Working Memory Training in Subjective Cognitive Decline
This 2-armed randomized, sham-controlled, single-blind study aims at providing evidence for the efficacy of a transcranial direct current stimulation (tDCS)-enhanced cognitive control training (PASAT) in participants with…
- Trial name
- NCT03236454
- Testing
- DC-Stimulator MC, NeuroConn
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Healthy Volunteers
Neurophysiological Study of tDCS Effects in Healthy Volunteers
Transcranial direct current stimulation is a tool to modulate cortical excitability.
- Trial name
- tDCSHV (NCT02125422)
- Testing
- Cefaly tDCS
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Liege
Aggression, Risk-Taking
Transcranial Direct Current Stimulation in Offenders
This study investigates the effect of upregulating prefrontal cortex activity on risk-taking, and antisocial and aggressive behavior in violent offenders.
- Conditions
- Aggression, Risk-Taking, Antisocial Behavior
- Trial name
- NCT03036683
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Olivia Choy
Cortical Excitability, Motor Performance
The Effect of tDCS on Motor Performance and Cortical Excitability
In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS…
- Conditions
- Cortical Excitability, Motor Performance, tDCS
- Trial name
- NCT01740843
- Testing
- transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Dysphagia, Swallowing Disorder
tACS and tRNS Studies on Brain Control of Swallowing
Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS) are two (CE marked medical devices) new, non-invasive (over the scalp) brain stimulation (NIBS) techniques.
- Trial name
- NCT04040803
- Testing
- Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS)
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Transcranial Electric Stimulation
Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking
This study is to find out whether and how a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity in healthy adults.
- Trial name
- MINT (NCT07752745)
- Testing
- TES-TI with hdEEG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy
Metaplasticity Experimental Design and Comparison of Motor Outcome Measure Sensitivity to Change
The overall objective is to validate the methodology of a metaplasticity experimental design by assessing change in motor excitability after administration of priming transcranial direct current stimulation (tDCS) followed by…
- Trial name
- NCT03304262
- Testing
- rTMS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Healthy
Consciousness Transcranial Alternative Electric STimulation
The aim of this study is to investigate the effect of transcranial Alternating Current Stimulation (tACS) at theta frequency and the the effect of transcranial Direct Current Stimulation (tDCS) on the conscious access to visual…
- Trial name
- CONTEST_1 (NCT03574883)
- Testing
- tACS, tDCS
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cyberaggression
Effects of Transcranial Direct Current Stimulation on Cyberaggressive Behaviour in Adults
This study examines whether transcranial direct current stimulation (tDCS), a non-invasive form of brain stimulation, influences cyberaggressive behaviour in adults.
- Trial name
- NCT07908862
- Testing
- Anodal transcranial direct current stimulation, Cathodal transcranial direct current stimulation
- Where
- Singapore
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Healthy Volunteers
Safety and Feasibility of St. Mark's Electrode for the Hypoglossal Nerve and Cortico-lingual Pathway Study
The possibility of registering the M-response and the motor evoked potential (MEP) from the muscles of the tongue by using the St. Mark's electrode will be evaluated. The safety of method will be confirmed.
- Trial name
- NCT05070273
- Testing
- Hypoglossal nerve conduction study, Transcranial magnetic stimulation of hypoglossal nerve
- Where
- Russia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Healthy
Transfer Effects of Combined Attentional Filter Exercise and Transcranial Direct Current Stimulation
Investigation of how a single session of an attentional filter exercise of distractor inhibition combined with tDCS modulates cognitive functions like working memory, decision making and attentional control.
- Trial name
- NCT03915483
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)