Clinical trials: Transcranial Direct Current Stimulation
Traumatic Brain Injury
Neural Basis of Decision-Making Deficits in Traumatic Brain Injury
Background: People with a traumatic brain injury (TBI) can have trouble making the best possible decisions. Researchers want to learn more about the parts of the brain that control decision making.
- Trial name
- NCT02169310
- Testing
- tDCS, [11C] Raclopride
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pain
Effects of Transcranial Direct Current Stimulation on Pain Perception
The purpose of this study is to determine whether a new medical technology can temporarily alter pain perception. The new technology is called Transcranial direct current stimulation (tDCS).
- Trial name
- tDCS-CBT (NCT01860950)
- Testing
- anodal tDCS, cathodal tDCS
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Multiple Sclerosis Subjects
Task-oriented Circuit Training Combined With Cerebellar tDCS in Multiple Sclerosis Subjects
Aims of the study: This is a double-blind randomized-controlled trial to test the effects of a task oriented training combined with cerebellar transcranial direct current stimulation on locomotor function, mobility and balance in…
- Trial name
- NCT01883310
- Testing
- real tDCS +TOCT
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Stuttering
Shaping Motor Neural Functioning of Developmental Stuttering to Improve Fluency
Developmental stuttering (DS) is a motor/speech disorder, characterized by specific alterations in the functioning of brain circuits.
- Trial name
- NCT05306782
- Testing
- transcranial Electrical Stimulation, Speech Therapy
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Cognitive Dysfunction, Alzheimer Disease
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy.
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
- Trial name
- NCT06733714
- Testing
- Transcranial Alternating Current Stimulation, Digital Cognitive Training
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Subthreshold Depression
tDCS in People With Subthreshold Depression
This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.
- Trial name
- NCT06517121
- Testing
- Personalized Experimental Transcranial Direct Current Stimulation (tDCS), Conventional Experimental Transcranial Direct Current Stimulation (tDCS)
- Where
- Hong Kong
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Healthy Adults
Investigating the Neural Correlates in Memory Retrieval After HD-tDCS
The overall objective of this study is to investigate the neural correlate in retrieval memory task. The aim of the study is to understand the undergoing changes in late positive ERP component during retrieval memory task when…
- Trial name
- NCT03319134
- Testing
- active anodal HD-tDCS, active cathodal HD-tDCS
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Seizures, Seizure Disorder
Modulating Movement Intention Via Cortical Stimulation
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies.
- Conditions
- Seizures, Seizure Disorder, Psychogenic Movement Disorder
- Trial name
- NCT03233399
- Testing
- rTMS of left or right angular gyrus (AG) or frontal cortex (FC), Anodal tDCS of left or right AG or FC
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy
Effects of Different Intensities of Bilateral- and Cathodal Transcranial Direct Current Stimulation in Healthy Individuals
This study will separate study to investigate the effects of 1 mA, 1.5 mA, and 2 mA of 1) bilateral- and 2) cathodal tDCS on cortical activity and motor learning in healthy individuals
- Trial name
- NCT05929014
- Testing
- study 1) Active bilateral-tDCS, study 2) active cathodal-tDCS
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Depressive Disorder, Major Depressive Disorder, Healthy Volunteer
Exploring the Role of the Prefrontal Cortex in Decision-Making
The goal of this study is to examine whether high-definition transcranial direct current stimulation (HD-tDCS) can influence decision-making for emotionally valenced content in younger and older adults, with or without major…
- Conditions
- Depressive Disorder, Major Depressive Disorder, Healthy Volunteer, Aging
- Trial name
- NCT07080489
- Testing
- Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/F4, Active high-definition transcranial direct current stimulation (HD-tDCS) - anodal F3/ kathodal F4
- Where
- Switzerland
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Bern
Auditory Hallucination, Verbal
Effects of Transcranial Direct Current Stimulation (tDCS) on Persistent Auditory Verbal Hallucinations in Schizophrenia
Many individuals with schizophrenia struggle with auditory verbal hallucinations (AVHs). In some cases, these AVHs can be resistant to medication treatment.
- Trial name
- NCT04222582
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Aging, Mild Cognitive Impairment
Implication of Cognitive Reserve in Non-pharmacological Intervention Outcomes
Cognitive reserve (CR) is defined as the gradual accumulation of neural resources and their adaptability (i.e., efficiency, capacity, flexibility) due to genetic and/or lifelong environmental factors that mitigate the cognitive…
- Conditions
- Aging, Mild Cognitive Impairment, Dementia With Lewy Bodies
- Trial name
- NCT06563453
- Testing
- transcranial alternating current stimulation
- Where
- Czechia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Healthy
a-tDCS Combined With Aerobic Exercise in Healthy Individuals
The purpose of this study is to assess the effects on the exercise performance of anodal transcranial direct current stimulation combined with aerobic exercise in healthy individuals.
- Trial name
- NCT04211779
- Testing
- Real tDCS, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy Volunteers
Rapid Eye Movement Restoration and Enhancement for Sleep-deprived Trauma-adaptation
The goal of this clinical trial is to find out whether stimulating the brain with electrical current during naps can increase certain kinds of brain activity that happen during sleep and lead to improvements in emotional health…
- Trial name
- REM-REST (NCT06547086)
- Testing
- Transcranial electrical stimulation with Temporal Interference (TES-TI)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Primary Progressive Aphasia
Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a neurodegenerative disease that affects first and foremost language abilities. There are three different variants of PPA, each a relatively distinct speech and language profile.
- Trial name
- NCT04486586
- Testing
- Active tDCS plus Speech-Language Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Effects on Learning
The Effect of Timing of Transcranial Direct Current Stimulation (tDCS) for Enhancing Learning During Cognitive Training
This project will investigate a novel strategy for enhancing cognitive training (CT). Specifically, the investigators aim to combine a non-invasive form of brain stimulation (tDCS) with CT.
- Trial name
- NCT01339585
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Healthy, Mild Cognitive Impairment
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Previous studies showed that anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) improved episodic memory performance, indicating a possible use as an intervention for patients suffering from memory impairments.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03227185
- Testing
- real anodal transcranial direct current stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Autism, Autism Spectrum Disorder
Cerebellum and Autism: Regional Specialization for Social and Executive Functions
The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.
- Trial name
- NCT05396352
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University
Stroke, Hemiparesis
Post Stroke Motor Learning
Noninvasive brain stimulations (NIBS) will be used in chronic stroke patients to improve motor learning. Functional magnetic resonance imaging will be used to evaluate the mechanisms underlying motor learning in healthy…
- Trial name
- NCT01519843
- Testing
- transcranial direct current stimulation tDCS, transcranial magnetic stimulation TMS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Chronic Pain
Effects of Transcranial Magnetic Stimulation (TMS) and Stimulus Controllability on Pain Perception
Although transcranial magnetic stimulation (TMS) is now considered a minimal risk intervention, is approved for the treatment of depression, and is widely used around the world, little is known about mechanisms of action of…
- Trial name
- NCT01030133
- Testing
- Operator Role Real TMS, Receiver Role Real TMS, All Participants Operator Role
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina