Clinical trials: Vitamin C
Iron Deficiency
Effect of Vitamin C on Iron Absorption
Iron deficiency is a common health problem worldwide. Ferrous fumarate (a form of iron) is often added to foods in an effort to prevent iron deficiency.
- Trial name
- NCT00570895
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Diarrhea
Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation
The study will be conducted as a community-based, randomized, placebo-controlled, trial with four study groups. The overall objective of the study is to determine the optimal method for delivering zinc to young children, both for…
- Trial name
- NCT02428647
- Testing
- MNP, preventive zinc supplement, therapeutic zinc supplement
- Where
- Laos
- Volunteers
- 3,433 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Preeclampsia
Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Preeclampsia is one of the most common complications of pregnancy and is characterized by high blood pressure and protein in the urine. This can cause problems in the second half of pregnancy for both the mother and fetus.
- Trial name
- CAPPS (NCT00135707)
- Testing
- Dietary Supplement/Vitamins
- Where
- 16 sites in United States
- Volunteers
- 10,154 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Vasodilation, Arterial Stiffness
Targeting ER Stress in Vascular Dysfunction
Aging and obesity are both risk factors for cardiovascular disease (CVD). One process that links both of these conditions to CVD is vascular dysfunction.
- Trial name
- NCT04001647
- Testing
- Acetylcholine, Sodium Nitroprusside, Ascorbic Acid
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Colorectal Cancer
The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer
Vitamin B-6, folate and homocysteine may play a critical role in the colorectal cancer progression. This is a 4-y study and the specific aims are: 1) to compare vitamin B-6, folate and homocysteine status, oxidative stress…
- Trial name
- NCT01426490
- Testing
- Vitamin C, Vitamin B6, Folic acid
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Vitamin C Deficiency
The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis
The effect of vitamin C supplementation on GCF total oxidant capacity in smoker patients with periodontitis following non-surgical periodontal therapy.
- Trial name
- NCT05009355
- Testing
- Vitamin C
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tissue Modification After Vit c Injection
Effect of Vitamin C on Collagen Production in Comparison to Hereditary Gingival Fibromatosis: Histopathological Study
In this preliminary study, we propose that the intraepidermic injection of vit C can induce quantitative and qualitative modification of the gingival biotype.
- Trial name
- NCT07043985
- Testing
- biopsy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Badr University
Nutrition Status
A Study to Assess the Impact of a Nutritional Supplement on Wellbeing and Nutrient Absorption
The objective of this placebo controlled randomized research is to demonstrate the health benefits of a carotenoid nutritional supplement as compared to placebo in terms of nutrient levels, quality of life, feelings, of wellness…
- Trial name
- NCT06749808
- Testing
- Carotenoid Nutritional Supplement
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Blood Pressure, Endothelial Dysfunction
Effect of Inorganic Nitrate Supplement on Blood Pressure
The primary purpose of this project is to assess the efficacy (effectiveness) of plant-based nitrate tablets to elevate nitric oxide in your system as measured by saliva and effect on lowering blood pressure (BP), supporting…
- Trial name
- NCT03909789
- Testing
- Plant based bioequivalent Nitrate supplementation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Hypercholesterolemia
Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic Humans
Limonoids are compounds found in citrus juices, seeds and peel. Some research shows that they reduce blood cholesterol and also reduce the incidence of several forms of cancer.
- Trial name
- NCT02011789
- Testing
- Citrus Limonoid Beverage
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Iron Absorption, Gut Microbiota
Iron Absorption From a Wheat-based Instant Cereal:Gut and Stable Isotope Studies in Kenyan Infants
The aim of this study is to measure the effect of a prebiotic (high dose/low dose) mixture at different doses within a wheat-based instant cereal, on fractional iron absorption (FIA), gut microbiota and inflammation after three…
- Trial name
- NCT03894358
- Testing
- FeFum and 7.5 g prebiotic mixture, FeFum and 3 g prebiotic mixture, Fefum and no prebiotic mixture
- Where
- Kenya
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Melanin Hyperpigmentation
Vitamin C Depigmenattion Versus Conventional Technique
Although physiologic gingival hyperpigmentation is not a pathologic condition, it is considered one of the main esthetic problems in dentistry.
- Trial name
- NCT03719274
- Testing
- vitamin c depigementation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetic Retinopathy
Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy
The present study aims to support previous research on antioxidant therapy effects in diabetic retinopathy outcome. The investigators intend to assess 180 patients with diabetic retinopathy in different stages (moderate, severe…
- Trial name
- NCT03702374
- Testing
- Combined antioxidant therapy
- Where
- Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Vitamin D Deficiency
Personalized Vitamin D Supplementation in European and African Americans
The proposed study is a randomized, double-blind, controlled, multi-center clinical trial of six months of daily oral vitamin D3 (cholecalciferol).
- Trial name
- NCT02362269
- Testing
- Vitamin D
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Iron Deficiency (Without Anemia)
Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption
Iron is involved in many vital metabolic processes such as oxygen transport, electron transport in cells, DNA synthesis and repair, and muscle metabolism.
- Trial name
- INSECTE (NCT06822062)
- Testing
- Meal A, Meal B, Meal C
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Distance University of Applied Sciences
Oxidative Stress, Cell-derived Microparticles
Pik Lenin High Altitude Research Expedition 2009
Exposure to hypobaric hypoxia demands maximum effort of the body and can lead to high altitude illnesses. Recently, there is rising interest on coagulation activation during trekking and mountaineering in higher regions and on…
- Trial name
- PLHARE (NCT01571687)
- Testing
- antioxidant supplements
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Common Cold
Encapsulated Juice Powder Concentrate for Preventing Common Cold Symptoms
The primary objective of this study is to determine the effect of an encapsulated juice powder concentrate on the number of days with at least moderate common cold symptoms over winter time.
- Trial name
- NCT00778648
- Testing
- Juice Plus
- Where
- Germany
- Volunteers
- 543 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cardiovascular Diseases, Cardiovascular Abnormalities
The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults
Cardiovascular diseases (CVD), primarily heart disease and stroke, are the leading causes of death and prescription drug use in Canada.
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormalities, Heart Attack, Stroke
- Trial name
- NCT03826914
- Testing
- CardioFlex Q10
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Stress
Differences by Sex and Genotype in the Effects of Stress on Executive Functions
The aim of this project is to test the effects of an environmental factor (mild stress) on prefrontal cortex (PFC) and the cognitive functions that depend on PFC (collectively called executive functions [EFs]), and to test our…
- Trial name
- NCT04273880
- Testing
- Methylphenidate, Vitamin C
- Where
- Canada
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Headache, Nausea
Evaluation of a Fixed Combination of Herbal Extracts to Prevent Symptoms Alcohol-induced Hangovers
The primary objective of the study is to test whether the tested Product LACIME Anti-hangover is effective in preventing the signs and symptoms of alcohol-induced hangover (such as headache, impaired memory, depression, anxiety…
- Conditions
- Headache, Nausea, Dizziness, Sleepiness
- Trial name
- LACIME (NCT04183842)
- Testing
- LACIME Anti-hangover
- Where
- Armenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Incara Lab