Clinical trials: completed, sponsored by Al-Azhar University
Dental Caries
Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics
There is limited data available on VITA AMBRIA glass ceramic , so this study is conducted to investigate the esthetic parameters of this new glass press system.
- Trial name
- NCT05437432
- Testing
- VITA AMBRIA, IPS e.max press
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Previous Endodontic Treatment Failure and Radiographically Confirmed Periapical Radiolucency
Efficacy of 810 nm Diode Laser Disinfection on Inflammatory Cytokines and Postoperative Pain After Endodontic Retreatment
The main cause of endodontic disorders is microbial infection. From the infected pulp tissue, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and…
- Trial name
- cytokines (NCT07141459)
- Testing
- 810 nm diode laser disinfection, Calcium Hydroxide Intracanal medication
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Labial Frenum Attachment, Gender Determination
Association Between Lip Print Patterns, Gingival Phenotype, Labial Frenum Attachment, And Gender Determination in A Group of Egyptians. A Cross Sectional Study.
This cross-sectional study aims to evaluate gingival phenotypes, cheiloscopic lip print patterns, and labial frenum attachment levels in healthy adult participants, and to investigate potential associations between these…
- Conditions
- Labial Frenum Attachment, Gender Determination, Lip Print
- Trial name
- NCT07854184
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Neck Pain, Neck Pain Musculoskeletal
Sleep Hygiene Plus Physiotherapy for Sleep and Disability in Chronic Neck Pain
This study investigates the effectiveness of a combined intervention that integrates sleep hygiene education with physiotherapy exercises in patients suffering from chronic neck pain.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Sleep Disturbances, Fatigue, Mental
- Trial name
- NCT07178496
- Testing
- Sleep Hygiene Techniques, conventional physiotherapy program, Control arm
- Where
- Palestinian Territories
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Low Back Pain
Pilates and Resistance Training for Pain, Disability, and Sleep in Chronic Low Back Pain
This study will investigate the effect of Pilates and resistance training on pain, disability, and sleep quality in patients with chronic low back pain and sleep disturbances.
- Trial name
- NCT07291934
- Testing
- Combined Intervention (Pilates + Resistance Training), Pilates, Control (Usual Care)
- Where
- Palestinian Territories
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
White Spot Lesion of Tooth
Effect of Diode Laser With Dye and Remineralizing Agent on Surface Area of White Spot Lesions by Using Digital Subtraction Radiograph Techniques.
The current study was conducted to compare effect of diode laser and perio green dye with reminerlizing agent on surface area white spot lesions by using digital subtraction radiographic techniques.
- Trial name
- NCT07818655
- Testing
- remin pro
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Inferior Alveolar Nerve Block in Children
Clinical Success of 12 mm Needle IANB in Children
This prospective single-arm pilot study will evaluate the clinical success of an inferior alveolar nerve block performed using a 12 mm 30-gauge extra-short dental needle in children aged 4 to 12 years.
- Trial name
- NCT07791082
- Testing
- 12 mm 30-Gauge Extra-Short Dental Needle
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class II Malocclusion
Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion
The present study was conducted to evaluate the outcomes of conventionl versus 3D printed twin block appliances in growth modification of class II malocclusion (comparative clinical study) in both groups.
- Trial name
- RCT (NCT07792525)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Immediate Implant Placement in Chronic Infected Socket
Efficacy of Mixture of Vancomycin With Xenograft for Immediate Implant Placement in Chronic Infected Socket
Adding local vancomycin to xenografts greatly benefits stability, bone density, and limits marginal bone loss in dental implants in infected socket.
- Trial name
- RCT (NCT07784075)
- Testing
- immediate dental implants Placement in Chronic Infected Socket
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
To Evaluate the Effectiveness of Intra-canal Nano-ketrolac as a Medicament in Reducing Post-endodontic Pain in Patients Undergoing Root Canal Treatment
The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain
After obtaining informed consent, the procedure begins with the administration of local anesthesia to ensure patient comfort. A standard approach involves using 2% lidocaine with 1:100,000 epinephrine, delivered either via…
- Trial name
- Post-Endodonti (NCT07064083)
- Testing
- intracanal nano-ketrolac, ketrolac gel
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periodontal Intrabony Defects, Stage III Grade B Periodontitis
Sub-junctional Pinhole Technique
Pinhole Regenerative Therapy (PRT) following minimally invasive non-surgical periodontal therapy (MINST) in the treatment of intrabony defects associated with Stage III Grade B periodontitis.
- Trial name
- PRT (NCT07763223)
- Testing
- Sub-junctional Pinhole Technique (S-PHT)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Metformin Gel, Bone Healing
Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region
To evaluate, by standardized radiographic follow-up, whether locally delivered 1% metformin gel improves bone healing around immediately placed dental implants augmented with GBR.
- Conditions
- Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss
- Trial name
- MET-GBR (NCT07770087)
- Testing
- Metformin 1% Topical Gel, immediate Dental Implant Placement With Guided Bone Regeneration
- Where
- 2 sites in Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acne
577-nm Diode Laser in the Treatment of Non -Inflammatory Acne
The aim of this study is to evaluate the clinical efficacy and safety of the 577 nm diode laser in the treatment of non -inflammatory acne.
- Trial name
- NCT06909344
- Testing
- 577 nm Diode laser
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periodontitis
Periodontitis Severity and Associated Factors Among Egyptian Males and Females
This cross-sectional study aims to evaluate and compare the severity of periodontitis between a group of Egyptian males and females.
- Trial name
- NCT07721337
- Testing
- Clinical Periodontal Examination and Questionnaire
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periodontal Diseases
Deep Learning-Based Measurement of Keratinized Gingiva Width Using Smartphone-Acquired Clinical Images
This study aims to develop and validate an artificial intelligence-based system for automated measurement of keratinized gingiva width using smartphone-acquired intraoral clinical photographs.
- Trial name
- NCT07689552
- Testing
- Artificial Intelligence-Based Keratinized Gingiva Width Assessment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Skeletal Class II Malocclusion, Mandibular Retrognathia
Fixed Versus Conventional Twin Block Appliances for Skeletal Class II Malocclusion
This study compares two types of dental appliances a fixed Twin Block appliance and a conventional (removable) Twin Block appliance used to treat a bite problem called skeletal Class II malocclusion in growing children and…
- Trial name
- NCT07687927
- Testing
- Conventional Twin Block Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Occlusion
Effects of Clear Aligners Versus Fixed Appliances on Occlusion After Treatment of Mild Anterior Crowding
The aim of this study is to evaluate effects of clear aligners versus fixed appliances on occlusion after treatment of mild anterior crowding a T-scan study.
- Trial name
- NCT05737290
- Testing
- Clear aligners, Fixed appliances
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Oral Microbial Load
Antibacterial Effect of Moringa Mouthwash in Children With Mixed Dentition Wearing Orthodontic Appliances
This randomized controlled study aims to evaluate the microbiological effectiveness of Moringa mouthwash in children with mixed dentition wearing removable orthodontic appliances.
- Trial name
- MOR-MW (NCT07536438)
- Testing
- Moringa mouthwash, Oral Hygiene Routine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Patients
Efficacy of Skeletally Anchored Modified Leaf Expander in Maxillary Molar Distalization
Background: Distalization in orthodontics is one of conservative treatment modalities that result in gaining space especially in dental orthodontic cases of class ΙΙ molar relationship.
- Trial name
- NCT07534072
- Testing
- skeletally anchored Modified Leaf Expander
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University