Clinical trials: sponsored by Boston University
Cardiovascular Disease
ROS Signaling in Endothelial Function
The vascular endothelium (inner lining of cells in blood vessels) normally prevents vasospasm and thrombosis by producing nitric oxide and other regulatory substances.
- Trial name
- NCT01037465
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boston University
Insulin Resistance
Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction
Physical inactivity induces vascular dysfunction and glucose intolerance during five days of bed rest. This study will investigate the effects of salsalate on these responses.
- Trial name
- NCT00553995
- Testing
- salsalate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston University
Vitamin D Deficiency, Hypovitaminosis A
A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
The goal of this investigator-initiated study is to determine whether the fortification of orange juice with vitamin D, vitamin A, and vitamin E will enhance the vitamin D, vitamin A, and vitamin E status children ages 6-10 that…
- Conditions
- Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
- Trial name
- NCT01909063
- Testing
- Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston University
Healthy
Evaluation of the Bioavailability of Vitamin D2 in Yeast and Bread
The objective of this study is to test the bioavailability of vitamin D in bread.
- Trial name
- NCT02720575
- Testing
- Consumption of capsule/bread with vitamin D
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV Infections
Impact of Anti-HIV Treatment on Labor Productivity and Costs in South Africa
The purpose of this study is to determine the impact of anti-HIV treatment on the work attendance of employed people in South Africa.
- Trial name
- NCT00270725
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Tobacco Cessation
Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
The purpose of this study is to determine whether public housing residents trained in Tobacco Cessation and Motivational Interviewing Techniques to become Tobacco Treatment Advocates(TTA) will be effective in increasing the quit…
- Trial name
- NCT01651611
- Testing
- Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcohol Craving
Quantitative EEG Assessment of Cue-Induced Changes in Brain Activity in Alcohol Use Disorders
Exposure to alcohol related cues, such as the sight of alcoholic drinks, may induce craving for alcohol in drinkers. In this study, the effects of exposure to (1) the pictures of alcoholic drinks and (2) the imagining of a scene…
- Trial name
- NCT01507909
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston University
Malnutrition, Child Development
Tools to Improve Parental Recognition of Developmental Deficits in Children
In this study, we aim to improve child nutrition by increasing parents' awareness of their children's physical growth. We use a cluster-randomized trial design to evaluate two interventions that provide parents with regular…
- Trial name
- NCT02242539
- Testing
- Height measurement poster, Community-based monitoring
- Where
- Zambia
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- Boston University
Medical Knowledge
The mCME Project:Delivering Continuing Medical Education for Community Health Workers Via SMS Text Messages
Community health workers (CHWs) provide essential basic medical care to hundreds of millions of people across the globe. CHWs offer a myriad of services including community sanitation, breast feeding counseling, family planning…
- Trial name
- mCME project (NCT02381743)
- Testing
- Group 2 intervention daily SMS bullet point, Group 3 intervention daily SMS bullet point
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Boston University
Stress Disorders, Post-Traumatic
Behavioral Treatments for Acute Stress Disorder In Firefighters
This study will develop a treatment for firefighters experiencing symptoms of acute stress disorder (ASD). Effective treatments may reduce immediate symptoms and prevent the development of more chronic conditions, such as…
- Trial name
- NCT00183508
- Testing
- Cognitive behavioral therapy, Psychoeducation
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Boston University
Omphalitis
Omphalitis Community Based Algorithm Validation Study
The objective of this study is to develop and test a simple community-based diagnostic algorithm for omphalitis in sub-Saharan Africa.
- Trial name
- OCAVS (NCT01687621)
- Testing
- Diagnostic Algorithm for Community Based Worker for Omphalitis
- Where
- Zambia
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- Boston University
Obesity
Evaluating the Link Between Neighborhood Environments and Obesity Among African American Women
African American women have higher rates of obesity than women of any other racial or ethnic group in the United States. Obesity can have many causes, including genetic and environmental factors.
- Trial name
- NCT00356707
- Where
- United States
- Volunteers
- 23,000 people, healthy volunteers welcome
- Sponsor
- Boston University
Early Pregnancy Failure, Miscarriage
MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure
The purpose of this study is to compare two combinations of drugs (mifepristone and misoprostol versus placebo and misoprostol) used for medical treatment for early pregnancy failure.
- Conditions
- Early Pregnancy Failure, Miscarriage, Fetal Demise, Anembryonic Pregnancy
- Trial name
- MiMi (NCT00468299)
- Testing
- Mifepristone and misoprostol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston University
Vertigo
Diagnosis Of Vertigo With New Imaging
The purpose of this study is to determine the potential usefulness of new functional MRI in diagnostic assessment of patients presenting with vertigo.
- Trial name
- NCT00593216
- Testing
- Functional MRI imaging
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Boston University
Mortality
Lufwanyama Neonatal Survival Project
We seek to determine whether we can reduce day 28 mortality in Zambian newborns by training traditional birth attendants a modified version of the neonatal resuscitation protocol (NRP) and by improving their abiltiy to identify…
- Trial name
- LUNESP (NCT00518856)
- Testing
- Neonatal resuscitation protocol, Standard of care
- Volunteers
- 3,559 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcoholism
The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects
This investigation will assess the effectiveness of topiramate in reducing ethanol consumption by alcohol dependent subjects. It also will seek to establish whether topiramate can be safely used in this population including…
- Trial name
- NCT00329407
- Testing
- Topiramate (Topamax)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Hypertension
Blood Pressure Lowering Effects of Grape Juice
Recent studies suggest that a diet rich in fruit and vegetables can lower blood pressure, and a number of lines of evidence suggest that grape products may have such an effect.
- Trial name
- NCT00302809
- Testing
- Concord Grape Juice
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston University
Abortion, Induced, Abortion, Second Trimester
A Pilot Study of Priming Before Induction Termination of Pregnancy
Induction termination of pregnancy (second trimester abortion) has a median time of 14 hours from the start of medication (misoprostol) to expulsion of the fetus.
- Trial name
- NCT00495560
- Testing
- Addition of misoprostol 25 mcg 12 hours before induction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boston University
Abortion, Induced, Abortion, Second Trimester
Mifepristone and Mid-Trimester Termination of Pregnancy
Mid-second trimester medical terminations of pregnancy require admission to the hospital for the length of time it takes a woman to abort.
- Trial name
- NCT00382538
- Testing
- Addition of mifepristone 200 mg 24 hours before induction
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston University
Motion Sickness
Effects of Transdermal Scopolamine on Occupational Performance
The purpose of this study is to determine the effects of Transdermal scopolamine vs. placebo on ship navigation performance under simulated heavy sea conditions.
- Trial name
- NCT00374478
- Testing
- Scopolamine
- Where
- Sweden
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Boston University