Clinical trials: completed, sponsored by Dana-Farber Cancer Institute
HPV Infection, HPV Positive Oropharyngeal Squamous Cell Carcinoma
The SPOT-HPV Study
The purpose of this research is to evaluate a new test for oral HPV DNA in saliva ('oral rinse test').
- Trial name
- NCT05524025
- Testing
- Salivary TTMV-HPV DNA Test, Blood TTMV-HPV DNA Test
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Hematologic Malignancy
Home Transfusion for HEME
The purpose of the research is to assess the feasibility and acceptability of a home blood transfusion program for patients with hematologic malignancies who need blood transfusions
- Trial name
- NCT05509439
- Testing
- Home Transfusion Program Components
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Advanced Cancer
Videos for Advance Care Planning in Young Adults
This study is a randomized trial of adolescent and young adults with advanced cancer and their caregivers to assess preferences for care in advanced cancer.
- Trial name
- NCT04149704
- Testing
- ACP video decision aid, Usual Care-
- Where
- 3 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Hematopoietic Cell Transplantation
Development and Piloting an Avatar-based Intervention to Support Patients Undergoing Stem Cell Transplantation
The goal of this research study is to provide an avatar-based technology during a subject's stay for participants who have been admitted to the hospital for reduced-intensity conditioning (RIC) allogeneic transplant.
- Trial name
- NCT05600101
- Testing
- Care.Coach
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer, Ovarian Cancer
Genetic Testing for Breast, Ovarian, Pancreatic, and Prostate Cancers
This study is evaluating the effect of two pre-test education methods on participants interested in genetic testing for hereditary cancer risk.
- Conditions
- Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Metastatic Prostate Cancer
- Trial name
- GeneBOPP (NCT04330716)
- Testing
- Standard Genetic Counseling, Educational Video
- Where
- 6 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer Survivor, Breast Cancer
Move Together Boston Feasibility Pilot (Sit Less, Move More App for Black Breast Cancer Survivors & At-Risk Relatives)
The purpose of this study is to develop and test a mobile app for Black/African American breast cancer survivors and their relatives, called Move Together, that promotes sitting less and moving more for better health.
- Conditions
- Breast Cancer Survivor, Breast Cancer, Fitness Trackers
- Trial name
- NCT05011279
- Testing
- Move Together app/Garmin Activity Tracker
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Ovarian Cancer
Stepping Into Survivorship: Harnessing Behavioral Economics to Improve Quality of Life in Ovarian Cancer
This research study will test whether using wearable fitness trackers with a social incentive, delivered through a game-based mobile health intervention, increases physical activity and quality of life in ovarian cancer survivors.
- Trial name
- NCT03364673
- Testing
- Fitness Tracker, Social Incentive (Way to Health)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Mindfulness, Meditation
My Mindful Moments: A Mindfulness Meditation and Digital Art Activity
The purpose of this evidence-based practice project is to evaluate the feasibility of providing a relaxation mindfulness meditation and an expressive digital arts activity among clinical staff at Dana Farber Cancer Institute .
- Trial name
- NCT04557033
- Testing
- Mindfulness intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Advanced Care Planning, Shared Decision Making
Advance Care Planning: Communicating With Outpatients for Vital Informed Decision
This Pre-Post, open-cohort design, pragmatic trial with 150 clinicians and will evaluate the effectiveness of the use of telehealth Advanced Care Planning (ACP) Program by comparing ACP documentation among 13,000 patients over 65
- Conditions
- Advanced Care Planning, Shared Decision Making, Video Decision Aids, Communication Skills
- Trial name
- ACP-COVID (NCT04660422)
- Testing
- VitalTalk communication skills training, ACP Decisions Video Program, Intervention training:
- Where
- United States
- Volunteers
- 42,019 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cancer, Chemotherapy-induced Peripheral Neuropathy
Clinician Decision Support Algorithm for Chemotherapy-Induced Peripheral Neuropathy
This research study is evaluating how well a decision support tool works to improve clinicians' use of recommended chemotherapy-induced peripheral neuropathy (CIPN) assessment and management strategies in participants receiving…
- Trial name
- NCT03514680
- Testing
- CIPN Assessment and Management Algorithm
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Understanding Barriers to Initiation and Adherence to Endocrine Therapy in Young Breast Cancer Survivors of Diverse Backgrounds
The overall goal of this study is to qualitatively explore how behavioral, cultural, psychosocial, and economic barriers and facilitators affect the decision to start and adhere to endocrine therapy (ET) among young breast cancer…
- Trial name
- NCT03447886
- Testing
- Phone interview
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Improving Surgical Decision-making in Young Women With Breast Cancer
The overall goal of this study is to qualitatively assess the surgical decision-making process from both the patient and physician perspective 1. Conduct short in-person interviews with young women prior to surgery 2.
- Trial name
- NCT02644382
- Testing
- qualitative data collection, survey, decision aid
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Non-Small-Cell Lung Carcinoma
Study of OSI-774 (Tarceva) in Previously Untreated Elderly Lung Cancer Patients
The primary purpose of this study is to determine whether the drug OSI-774 is less toxic and potentially as good as or better than standard chemotherapy drugs, when given to subjects with non-small cell lung cancer, who are 70…
- Trial name
- NCT00137800
- Testing
- OSI-774 (Tarceva)
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cancer
Improving Communication Between Cancer Patients & Oncologists
The overarching goal of this project is to improve communication between oncologists and their patients by ensuring that the patient's voice is heard in the medical encounter.
- Trial name
- NCT02969031
- Testing
- Enhanced SCOPE training, Standard Communication training
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cancer
Promoting Organizational Capacity to Implement Cancer Control Programs Among Latino Churches
This research study aims to develop an organizational-level intervention to enable communities to adopt, adapt, implement and sustain evidence-based interventions (EBIs) to address cancer disparities among Latinos.
- Trial name
- CRUZA (NCT01740219)
- Testing
- Capacity Enhancement, Standard Dissemination
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
End of Life Care, Cancer
Serious Illness Communication Project
The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions.
- Trial name
- NCT01786811
- Testing
- Training
- Where
- United States
- Volunteers
- 994 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Health Behavior, Risk Reduction Behavior
Multiple Risk Behavior Intervention in Health Care Settings
This study (aka Healthy Directions2 or HD2) builds on an earlier study titled Healthy Directions (aka Healthy Directions 1 or HD1).
- Trial name
- HD2 (NCT01415492)
- Testing
- HD2, HD2+
- Where
- United States
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Cerebellar Neoplasm
Impact of Cerebellar Mass Resection on Pain Processing
The purpose of the study is to evaluate how cerebellar resection surgery may affect pain sensation and the way the brain "reads" pain signals.
- Trial name
- NCT02261649
- Testing
- Medoc Advanced Medical Systems PATHWAY Model ATS, Cold water bath, MRI scanner
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Gastrointestinal Cancers, Prostate Cancer
Vitamin D for Chemoprevention
This study will help us know the effects of Vitamin D pills in Blacks. The results of this study may be the first step in creating ways to prevent the risks of colon and prostate cancer.
- Conditions
- Gastrointestinal Cancers, Prostate Cancer, Hypertension
- Trial name
- NCT00585637
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Skin Cancer
Skin Cancer Screening and Education at Beaches
This study was an evaluation of the Dana-Farber Cancer Institute Blum Family Resource Center Van's existing skin cancer screening and education program. This program occurred over 2 summers.
- Trial name
- SHADE (NCT00894855)
- Testing
- education about sun protection, biometric feedback, dermatologist skin exam
- Where
- United States
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute