Clinical trials: sponsored by Federico II University
Thalassemia
The Role of OCTA in Patients Affected by Beta Thalassemia
To investigate, using optical coherence tomography angiography (OCTA), the retinal and choriocapillaris vascular features in patients affected by Beta Thalassemia.
- Trial name
- NCT04582110
- Testing
- Optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Federico II University
Covid19
OCTA Study: Retinal Vascular Changes in Patients With SARS-CoV-2 Infection
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that have been affected by COVID-19.
- Trial name
- NCT04601012
- Testing
- Optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Age Related Macular Degeneration
OCTA and Retinal Angiomatous Proliferation
To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.
- Trial name
- NCT04689789
- Testing
- optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federico II University
Bariatric Surgery Candidate
OAGB-MGB Conversions for Post-operative Complications
Laparoscopic mini/one anastomosis gastric bypass (MGB/OAGB) is a relatively new bariatric procedure and is gaining ground over the surgical approach for morbid obesity as a safe and effective operation.
- Trial name
- NCT04641715
- Testing
- OAGB-MGB
- Where
- Italy
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Federico II University
Satiety Response, Carbohydrate Metabolism
Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic Effects
Seawater is rich in minerals which may help confer good palatability to foods, favouring the use of smaller amounts of salt, a recognized measure of cardiovascular prevention.
- Conditions
- Satiety Response, Carbohydrate Metabolism, Sodium Retention
- Trial name
- NCT04629742
- Testing
- Seawater Pizza, Standard pizza
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federico II University
Labor Pain
Trial of Music During Labor and Delivery
The use of music is widely supported in various areas of medicine: first of all in the psychiatric field as in the treatment of autism in children, obtaining surprising results even on Alzheimer's patients, or the unparalleled…
- Trial name
- NCT03779386
- Testing
- music
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federico II University
Ocular Injury
Study of Retinal Vascular Changes After Ocular Blunt Trauma
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.
- Trial name
- NCT04546997
- Testing
- Optical Coherence Tomography Angiography
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federico II University
Autism Spectrum Disorder
Improving Daily Living Skills in People With Autism Spectrum Disorder Through a Personalised Serious Game
This study evaluates the efficacy of a rehabilitation intervention for people with Autism Spectrum Disorder through an individualised serious game developed for improving skills related to a specific daily living activity…
- Trial name
- NCT04295746
- Testing
- Serious Game ShopAut
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Pituitary Adenoma
Evaluation of Early Retinal Vascular Modifications After Endoscopic Endonasal Pituitary Surgery
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received endoscopic endonasal approach for the removal of an intra-suprasellar pituitary adenoma compressing the…
- Trial name
- NCT04425954
- Testing
- Endoscopic Endonasal Pituitary Surgery
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Federico II University
Change in Flow Mediated Dilation
Effects of FSH on Endothelial Function (FEND)
Purpose of the study will be to evaluate the effects of the s.c. administration of 300 IU of FSH in 16 healthy males. The endothelial function will be evaluated by the measurement with ecographic approach of the flow mediated…
- Trial name
- FEND (NCT04430621)
- Testing
- Follicle Stimulating Hormone
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federico II University
Prosthesis Survival
14y Prospective Study on Posterior Zirconia-based 3-unit FDPs
The main objective of the present prospective study is to evaluate the effectiveness of posterior zirconia FDPs after 14 years of function.
- Trial name
- NCT04374201
- Testing
- 2 zirconia FDPs, 1 zirconia FDP
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Federico II University
Laparoscopic Right Colectomy
Surgical Stress and Intracorporeal Anastomosis
The short-term advantages of minimally invasive colon resection have been well established in several randomized trials. A major factor in the development of morbidity is the surgical stress response with subsequent increased…
- Trial name
- NCT03422588
- Testing
- Laparoscopic right colectomy
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federico II University
Postprandial Hyperglycemia
Metabolic Effects of High-amylose Wheat-based Breads
The amylose-amylopectin ratio influences starch properties. A higher amylose content is associated with slower starch digestion thus reducing the postprandial plasma glucose response and improving the overall postprandial…
- Trial name
- NCT03899974
- Testing
- Test meal
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federico II University
Cardiovascular Risk Factors
Effects of LopiGLIK® on Cardiovascular Risk
The study is designed to compare the effects of two combination of nutraceuticals: Armolipid Plus® and LopiGLIK® (Akademy Pharma), a new supplement that, in addition to Berberine and Red Rice, contains Morus Alba's extract.
- Trial name
- LopiWEB (NCT02898805)
- Testing
- Prescribed Diet, LopiGLIK®, Armolipid Plus
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Federico II University
Cardiovascular Risk Factor
Effects of a New Combination of Nutraceuticals (AkP06) Without Monacolin K on Plasma Lipids and Glucose
The study is designed evaluate the effects of a new combination of nutraceuticals (AkP 06) without Monacolin K on lipid and glucose metabolism.
- Trial name
- NCT03340285
- Testing
- AkP06
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hypercholesterolemia, Endothelial Dysfunction
Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve
Hypercholesterolemia is considered one of the most important cardiovascular risk factors. Cardiovascular prevention include a class I indication to statins in addition to non-pharmacologic intervention and prevention strategies…
- Trial name
- NUTRENDO (NCT02969070)
- Testing
- LopiGLIK™ therapy, Armolipid Plus® therapy
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federico II University
Safety and Efficacy of Tattooing Substance
Endoscopic Tattooing and Colorectal Cancer
Endoscopic tattooing to facilitate colorectal lesions' identification during laparoscopic surgery is a reliable and widely used technique. India Ink is the standard option for colonic tattoing.
- Trial name
- NCT03637933
- Testing
- endoscopic tattooing
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hidradenitis Suppurativa, Mediterranean Diet
Nutritional Status and Hidradenitis Suppurativa (Acne Inversa)
Hidradenitis suppurativa (HS) is a chronic inflammatory, debilitating skin disorder. The exacerbating factors of HS include nutrition and adiposity.
- Conditions
- Hidradenitis Suppurativa, Mediterranean Diet, Body Composition, Vitamin D Deficiency
- Trial name
- NutriHidra (NCT03683238)
- Testing
- Mediterranean Diet
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Federico II University
Acute Diarrhea
Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea
A pilot, randomized, case-controlled trial was conducted in 60 children affected by AG (< 7 days) with mild-moderate dehydration, according to WHO recommendations, from1 year to 17 years old.
- Trial name
- NCT03356327
- Testing
- Actitan F, Standard Oral Rehydration
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hyperglycemia
Metabolic Effects of High-amylose Wheat-based Rusks.
Amylose-amylopectin ratio may influence the rate of starch digestion. This randomized controlled study evaluated the postprandial metabolic effects of amylose-rich- wheat- based rusks in overweight subjects.
- Trial name
- NCT02702934
- Testing
- Test meal
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University