Clinical trials: sponsored by Fudan University
Congenital Heart Disease
Application of Ultrasound Technique in Locating the End of the Gastric Tube in Children Aged 0-6 Years
Application of ultrasound technique to locate the end of the gastric tube in children aged 0-6 years
- Trial name
- NCT06650787
- Testing
- Ultrasound was used to locate the end of the gastric tube, Conventional placing nasogastric tube group
- Where
- China
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Colorectal Neoplasms, Colonoscopy
AI-empowered Nudge to Improve Colonoscopy Uptake (AINC)
Colorectal cancer (CRC) ranks third in both incidence and mortality among all malignant tumors in China. Studies have shown that early screening can significantly reduce its incidence and mortality.
- Trial name
- NCT07612436
- Testing
- AI-empowered nudge (AINC) strategy, Usual Care
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Fudan University
Helicobacter Pylori Eradication, Adverse Reaction
Tegoprazan-Based Therapies for H. Pylori Eradication: A Randomized Controlled Trial
Current first-line Helicobacter pylori eradication protocols involve multidrug regimens comprising a proton pump inhibitor (PPI) or bismuth agent combined with dual antibiotics (e.g., clarithromycin, amoxicillin, quinolones…
- Trial name
- NCT06977841
- Testing
- Tegoprazan, Amoxicillin, Tetracycline
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital (Xiamen), Fudan University
Cognitive Function, Mood Disorders
RCT on the Neurobehavioral Effects of Fruits and Vegetables in Shanghai Children
This project proposal outlines a randomized-controlled trial (RCT) aimed at evaluating the effects of increased fruit and vegetable (F\&V) intake on cognitive performance, attention, and mood in Chinese children aged 7-11…
- Conditions
- Cognitive Function, Mood Disorders, Attention-deficit
- Trial name
- NCT06560359
- Testing
- F&V, No F&V
- Where
- China
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Fudan University
Intestinal Functional Disorder, Inflammation
The Antagonistic Effect of Composite Polyphenols on Health Damage Caused by Environmental Pollutants
The study attempts to conduct randomized controlled trials to understand whether daily exposure to environmental pollutants can cause harm to human health, explore whether the intake of composite polyphenols can alleviate…
- Trial name
- NCT06437119
- Testing
- Compound plant nutrients
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Fudan University
Kidney Diseases, Diagnostic Techniques
Urine and Ultrasound Screening for Kidney Disease in Children
The aim of this study is to early detect kidney disease in the natural population cohort of children by urine and ultrasound screening, to assist in the precise prevention and treatment of children's kidney disease, and to…
- Conditions
- Kidney Diseases, Diagnostic Techniques, Ultrasound, Urinalysis
- Trial name
- NCT06018831
- Testing
- Urine and Ultrasound Screening
- Where
- 2 sites in China
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Pancreatic Neuroendocrine Tumor, Solid Pancreatic Neoplasms
Plasma cfDNA Fragmentomics for Early pNET Detection and Differential Diagnosis of Solid Pancreatic Tumors
This prospective study aims to evaluate the sensitivity and specificity of an integrated model using fragmentomic profiles of plasma cell-free DNA for early detection of pancreatic neuroendocrine tumors and differential diagnosis…
- Trial name
- NCT05847855
- Testing
- Blood collection
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Inguinal Hernia Repair, Mesh Infection
Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis
Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required.
- Trial name
- NCT07491250
- Testing
- Complete mesh removal, Partial mesh removal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fudan University
Interstitial Lung Diseases of Childhood, Genetic Testing
Genetic Causes and Clinical Features of Childhood Interstitial Lung Diseases in China
Recruitment of a carefully characterized cohort of chILD patients, to generate a database and biobank via collecting data on chILD in China.
- Trial name
- NCT03869515
- Testing
- No intervention
- Where
- China
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Newborn, Hereditary Disease
The China Neonatal Genomes Project
The project will carry out the genetic testing of 100000 neonates in the next 5 years. The aim of the project is to construct the Chinese neonatal genome database, establish the genetic testing standard of neonatal genetic…
- Conditions
- Newborn, Hereditary Disease, Genetic Predisposition to Disease, Defect, Congenital
- Trial name
- CNGP (NCT03931707)
- Testing
- Genomic sequencing
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism or Autistic Traits, Healthy
Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD
The goal of this observational study is to compare the developmental trajectories of prosocial behaviors and functional network connections in infants and toddlers at high and low risk of autism spectrum disorder (ASD).
- Trial name
- NCT06329245
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Skin Health
Ozone Reaction Products and Skin Health
This is a randomized controlled human exposure study. Investigators aim to investigate the products of ozone-sebum reactions and their acute effects on skin health of healthy young adults.
- Trial name
- NCT06932419
- Testing
- Ozone exposure, Clean air exposure
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric Adenocarcinoma
An Observational Study on Gastric Cancer in High-risk Individuals
This study is designed as a prospective observational cohort study, aiming to assess the differences in the occurrence of gastric cancer and the progression of gastric cancer-related precancerous lesions between individuals who…
- Trial name
- NCT07438418
- Testing
- The result of fecal multi-target DNA testing
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric (Stomach) Cancer
Eradication of Helicobacter Pylori Subtypes at High Gastric Cancer Risk: a Cluster-randomized Controlled Trial
This study is a prospective, multicenter cluster randomized controlled trial. Additional fecal screening for high-risk SNP subtypes, in conjunction with routine Hp testing, may improve the identification of individuals at high…
- Trial name
- NCT06943794
- Testing
- recommendations for Hp eradication treatment
- Where
- China
- Volunteers
- 4,824 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric Adenocarcinoma, Helicobacter Pylori
Prospective Gastric Cancer Screening Using Helicobacter Pylori High-Risk Single Nucleotide Polymorphism Detection
This is a prospective study designed to compare the performance of fecal H. pylori gastric cancer susceptibility analysis and the gastric cancer risk questionnaire for the early detection of gastric cancer.
- Trial name
- NCT06943781
- Testing
- Fecal Helicobacter pylori gastric cancer susceptibility gene test
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric (Stomach) Cancer
Prospective Gastric Cancer Screening With Fecal Multi-target DNA Analysis
This is a prospective study designed to evaluate the efficacy of a multi-target fecal DNA test for the early detection of gastric cancer.
- Trial name
- NCT06943807
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric (Stomach) Cancer, Helicobacter Infection
An Observational Study for Gastric Cancer in Carriers of High Risk Helicobacter Pylori
This study is intended to be a prospective observational cohort study. The incidence of gastric cancer and progression of gastric precancerous lesions will be compared between groups through prospective follow-up of a population…
- Trial name
- NCT06896370
- Testing
- observational study
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Breast Cancer Screening
AI-Enhanced Imaging in Population Breast Cancer Screening
Artificial Intelligence (AI)-assisted imaging technologies (including AI-assisted breast ultrasound and AI-assisted mammography) can effectively improve the accuracy and efficiency of breast imaging examinations, but their…
- Trial name
- NCT07411443
- Testing
- AI-assisted screening
- Where
- China
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastric (Stomach) Cancer
Fecal DNA Methylation and Helicobacter Pylori SNPs Tests for Gastric Cancer
Based on the detection technology of methylation sites in feces, combined or not combined with Helicobacter pylori gastric cancer susceptibility gene detection, an early diagnosis and detection system for gastric cancer is…
- Trial name
- NCT07312500
- Testing
- Diagnostic Test: fecal methylation site-based testing and fecal Helicobacter pylori gastric cancer susceptibility gene-based testing
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Nasopharyngeal Carcinoma (NPC)
Individualized Neck Cervical Irradiation Prophylaxis Trial of NPC
Based on the pattern of nasopharyngeal carcinoma cervical lymph node metastasis, which typically follows a sequential downward spread with rare skip metastases and a tendency for ipsilateral neck involvement, and in accordance…
- Trial name
- INCIPT-NPC (NCT07303023)
- Testing
- Individualized Neck Irradiation, Standard Neck Irradiation
- Where
- 6 sites in China
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- Fudan University